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39 Cards in this Set

  • Front
  • Back
what is DM?
Diabetes Mellitus
how does type 1 diabetes work?
beta cell destruction leading to absolute insulin deficiency, autoimune, idiopathic.
how does type 2 diabetes work?
ranges from insulin resistance with insulin deficiency to secretory deficit with insulin resistance.
name specific conditions of hyperglycemia!
beta cell function, insulin action, pancreatitis,
what is gestational diabetes mellitus(GDM)?
glucose intolerance with onset or first recognition during pregnancy, diagnosis is based on results of a 100g oral glucose tolerance test during pregnancy.
what is Glucagon?
its a counter regulatory hormone that has actions opposite to those of insulin. it causes release of glucose from cell storage sites when ever blood glucose levels are low.
what does DM stand for?
Diabetes Mellitus
where does insulin transport glucose to?
muscle, liver and fat cells
true or false
it costs 2.5 times more to take care of a pt with DM!
true
what is the seventh leading cause of death?
Diabetes
how many units of insulin per day are going into the Liver?
40 to 50 units
causes of hyperglycemia?
Not enough insulin or inadequate insulin action.
what does Mellitus means?
Sweet
what does diabetes means?
Running water
what is DM?
a group of elevated levels of metabolic disease of elevated levels of glucose in the blood resulting from defects in insulin secretion, insulin action or both.
Cells that promote glucose production!
pancreatic alpha-cells
During Fasting state when the stomach is empty Plasma glucose is maintained between what parameters?
70 and 100 mg/dL
True or False
fatty acids can be used as fuel when glucose is absent!
true
What is the main fuel for the CNS Cells
Glucose
Ketogenesis
Conversion of Fats To Acids
Gluconeogenesis
Conversion of protein to glucose
Parandial Insulin Secretion
Increased Levels After Eating
Basal Insulin Secreation
Low levels during Fasting
how does type 2 diabetes work?
Hyper glycemia results from excessive glucose production and reduced glucose uptake in to the cells due to combination of insulin resistant and deficient insulin secretion.
name specific conditions of hyperglycemia!
beta cell function, insulin action, pancreatitis
what is gestational diabetes mellitus(GDM)?
glucose intolerance with onset or first recognition during pregnancy, diagnosis is based on results of a 100g oral glucose tolerance test during pregnancy.
what is Glucagon?
its a counter regulatory hormone that has actions opposite to those of insulin. it causes release of glucose from cell storage sites when ever blood glucose levels are low.
what is type 1 diabetes
beta cell destruction leading to absolute insulin deficiency, autoimune, idiopathic.
what does DM stand for?
Diabetes Mellitus
what is Metabolic syndrome?
Abdominal obesity w/ waist circ>40 inches in me and >35inches in woman, w/ triglicerides >150mg/dL, HDL cholesterol <40,BP >130/85, fasting BG>100mg/dL, acanthosis nigricans.
What is the Autoimmune problem w/ diabetes type 1
Selective destruction of B-cells by t-cells and antibodies.
what plasma hormones regulate glucose?
Insulin, glucagon, epinephrine, cortisol and growth hormones.
Normal plasma glucose is?
70-100mg/d
Glycogenesis
promotes storage of glycogen in the liver.
what lowers blood sugar levels and transports glucose from blood into cells?
Insulin
Glycogeneolysis
glycogen broken down to glucose.
what causes release of glucose from cell storage sites when blood glucose is low?
Glucagon
what product is secreted by alpha cells in response to decrease blood sugar!
Glucagon
where does insulin transport glucose to?
muscle, liver and fat cells