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18 Cards in this Set
- Front
- Back
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SLE & Scleroderma |
Chronic inflammatory autoimmune disorder of connective tissue |
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SLE - Skin |
Discoid
Butterfly/coin-like rash
oral/nasal lesions |
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Scleroderma - Skin |
Raynaud's phenomenon
Thick, hard
Taut, smooth, shiny
Loss of elasticity/movement
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SLE - Systemic Effect |
Multiple organ involvement
Arthritic changes
Pericarditis, pleural effusion, renal disease |
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Scleroderma - Systemic Effect |
CREST Syndrome
Calcinosis - calcium deposits in the tissues Raynaud's phenomonon - spasm of vessels in response to cold/stress; causes skin to become white Esophageal dysmotility - acid reflux and descrease in mobility of esophagus; causes difficulty swallowing and esophageal dilation Sclerodactyly - thickening/tightening of skin on hands and fingers casuing edema and pain Telangiestasia - capillary dilation that causes spider-like hemangiomas mainly on plams and face |
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Calcinosis
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calcium deposits in the tissues |
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Raynaud's phenomonon |
spasm of vessels in response to cold/stress; causes skin to become white
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Esophageal dysmotility |
acid reflux and descrease in mobility of esophagus; causes difficulty swallowing and esophageal dilation |
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Sclerodactyly |
thickening/tightening of skin on hands and fingers casuing edema and pain |
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Telangiestasia |
capillary dilation that causes spider-like hemangiomas mainly on plams and face |
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SLE - Patho |
Autoantibodies produced against the blood cells and/or organs; results in disturbed immune regulation and deposits of damaging immune complexes in the tissues |
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Sclerodrema - Patho |
Lymphokines stimulateprocollagen; results in insoluable collagen deposits
Inflammatory response causes edema
Fibrotic changes in skin and eventually organs |
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SLE - Diagnostics |
(+) ANA
Pancytopenia
(+) CRP & ESR |
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Scleroderma - Diagnostics |
Skin Bx
(+) ANA
(+) ESR |
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SLE - Tx |
NSAIDS, steroids
Antirheumatoid
Antimalarial - Plaquenil (causes visual changes - see meds cards)
Cytotoxins/antineoplastics - methotrexate
Plasmapheresis |
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Scleroderma - Tx |
NSAIDS, steroids
Antirheumatoid - penicilliamine (Cuprimine)
Antiinfective - minocycline (Minocin); thought to decrease collagen thickening |
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SLE - Nursing Care |
Assess for worsening of disease/SE of meds
Assess for kidney failure - check labs, changes in urine, may need low protein diet
Education - meds, signs of infection
Emotional support |
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Scleroderma - Nursing Care |
Assess for worsening of disease/SE of meds
Protect digits - keep warm/wear gloves
Education - smoking cessation, exercise, meds
Emotional support |
