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32 Cards in this Set

  • Front
  • Back
Changes in electrolyte concentration affect:
electrical activity of nerve & muscle cells

cause shifts of fluid from one compartment to another
Total Body Water (TBW)
sum of fluids withing all body compartments

60% of body weight
Primary sources of body water
drinking
ingestion of water in food
water derived from oxidative metabolism
Primary sources of water loss
renal excretion
stool
vaporization from skin & lungs
Capillary hydrostatic pressure (blood pressure)
facilitates the outward movement of water from the capillary to the interstitial space.
Capillary oncotic pressure
osmotically attracts water from the interstitial space back into the capillary.
Interstitial hydrostatic pressure
facilitates the inward movement of water from the interstitial space into the capillary.
Interstitial oncotic pressure
osmotically attracts water from the capillary into the interstitial space.
Water movement between ICF & ECF

What ions are responsible?
Sodium is responsible for the ECF osmotic balance
Potassium maintains the ICF osmotic balance.
Edema
the excessive accumulation of fluid within the interstitial spaces.
Forces that move fluid from capillaries/lymphatic channels
increased capillary hydrostatic pressure, lowered plasma oncotic pressure, increased capillary membrane permeability, lymphatic channel obstruction
albumin plays what role
lost or diminished plasma albumin production contributes to decreased plasma oncotic pressure
ascites
accumulation of fluid in the peritoneal space
S/S Edema
weight gain, swelling, puffiness
water balance regulated by
ADH
sodium regulated by
aldosterone
main ECF cation
sodium
major ECF anion
Chloride
Natriuretic hormone (peptide) does what
lowers BP by promoting urinary excretion of sodium & water, reduce aldosterone
Isotonic fluid loss
(isotonic dehydration)
causes contraction of the ECF volume
Isotonic fluid excess
hypervolemia/weight gain

normally through excessive admin of IV fluids
Hypertonic alterations
ECF hypertonicity attracts water from the intracellular space, causing ICF dehydration
Hypernatremia
too much sodium
cause intracellular dehydration
may cause hypervolemia
Hypernatremia
S/S
thirst, fever, dry mucous membranes, restlessness, muscle twitching, hyperreflxia, convulsions
Hyperchloremia
too much sodium or too little bicarbonate
Hyponatremia
sodium deficit caus hypoosmolality with movement of water into cells
Hyponatremia
S/S
lethargy, confusion, apprehension, depressed reflexes, seizures, coma
major intracellular electrolyte
Potassium
Hypokalemia
potassium loss from cell into ECF
Hypokalemia
S/S
skeletal muscle weakness, smooth muscle atony, cardiac dysrhythmia
Hyperkalemia
increased ECF potassium level
Hyperkalemia
S/S
restlessness, intestinal cramping, diarrhea, muscle weakness, paralysis, more rapid re polarization of heart muscle