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32 Cards in this Set
- Front
- Back
Changes in electrolyte concentration affect:
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electrical activity of nerve & muscle cells
cause shifts of fluid from one compartment to another |
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Total Body Water (TBW)
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sum of fluids withing all body compartments
60% of body weight |
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Primary sources of body water
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drinking
ingestion of water in food water derived from oxidative metabolism |
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Primary sources of water loss
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renal excretion
stool vaporization from skin & lungs |
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Capillary hydrostatic pressure (blood pressure)
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facilitates the outward movement of water from the capillary to the interstitial space.
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Capillary oncotic pressure
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osmotically attracts water from the interstitial space back into the capillary.
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Interstitial hydrostatic pressure
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facilitates the inward movement of water from the interstitial space into the capillary.
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Interstitial oncotic pressure
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osmotically attracts water from the capillary into the interstitial space.
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Water movement between ICF & ECF
What ions are responsible? |
Sodium is responsible for the ECF osmotic balance
Potassium maintains the ICF osmotic balance. |
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Edema
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the excessive accumulation of fluid within the interstitial spaces.
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Forces that move fluid from capillaries/lymphatic channels
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increased capillary hydrostatic pressure, lowered plasma oncotic pressure, increased capillary membrane permeability, lymphatic channel obstruction
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albumin plays what role
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lost or diminished plasma albumin production contributes to decreased plasma oncotic pressure
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ascites
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accumulation of fluid in the peritoneal space
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S/S Edema
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weight gain, swelling, puffiness
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water balance regulated by
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ADH
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sodium regulated by
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aldosterone
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main ECF cation
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sodium
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major ECF anion
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Chloride
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Natriuretic hormone (peptide) does what
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lowers BP by promoting urinary excretion of sodium & water, reduce aldosterone
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Isotonic fluid loss
(isotonic dehydration) |
causes contraction of the ECF volume
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Isotonic fluid excess
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hypervolemia/weight gain
normally through excessive admin of IV fluids |
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Hypertonic alterations
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ECF hypertonicity attracts water from the intracellular space, causing ICF dehydration
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Hypernatremia
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too much sodium
cause intracellular dehydration may cause hypervolemia |
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Hypernatremia
S/S |
thirst, fever, dry mucous membranes, restlessness, muscle twitching, hyperreflxia, convulsions
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Hyperchloremia
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too much sodium or too little bicarbonate
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Hyponatremia
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sodium deficit caus hypoosmolality with movement of water into cells
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Hyponatremia
S/S |
lethargy, confusion, apprehension, depressed reflexes, seizures, coma
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major intracellular electrolyte
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Potassium
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Hypokalemia
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potassium loss from cell into ECF
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Hypokalemia
S/S |
skeletal muscle weakness, smooth muscle atony, cardiac dysrhythmia
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Hyperkalemia
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increased ECF potassium level
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Hyperkalemia
S/S |
restlessness, intestinal cramping, diarrhea, muscle weakness, paralysis, more rapid re polarization of heart muscle
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