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28 Cards in this Set
- Front
- Back
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AUTONOMIC NS 2 PARTS
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PARASYMPATHETIC AND SYMPATHETIC
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PARASYMPATHETIC
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REST AND DIGEST
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SYMPATHETIC
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FIGHT OR FLIGHT
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PARASYMPATHETIC ALSO KNOWN AS
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CHOLINERGIC
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CHOLINERGIC DRUGS _______ THE _________ RESPONSE
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INHIBIT PARASYMPATHETIC
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ANTICHOLINERGIC DRUGS
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BLOCK PARASYMPATHETIC RECEPTORS
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ACETYLCHOLINE
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PRESYNAPTIC AND POSTSYNAPTIC NUEROTRANSMITTER
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ACETYLCHOLINE
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NEUROTRANSMITTER FOR PARASYMPATHETIC / CHOLINERGIC
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2 CHOLINERGIC RECEPTORS
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NICOTINIC
MUSCARINE |
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NICOTINIC DOES WHAT?
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WHEN INHIBITED, RE;EASES EPI, WHICH = MUSCLE CONTRACTION
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MUSCARINE DOES WHAT?
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WHEN INHIBITED, = VASODILATION= DECREASE BP
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PATHOPHYSIOLOGY OF PARASYMPATHETIC / CHOLINERGIC DRUGS
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PROVIDE EXTRA CHOLINERGIC STIMULATION (TO ENHANCE REST AND DIGEST RESPONSES) OR TO BLOCK (ANTICHOLINERGIC) ANS FUNCTIONS
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WHAT RESPONDS TO PARASYMPATHETIC DRUGS?
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BRONCHI, CARDIOVASCULAR, GTI, BLADDER, GLANDS, EYES
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DRUGS THAT MIMIC ACh
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CHOLINERGIC
PARASYMPATHOMIMETICS CHOLINERGIC AGONISTS CHOLINERGIC STIMULANTS ANTICHOLINERGIC |
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ANTAGONIST
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BLOCK
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AGONIST
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STIMULATE/ENHANCE
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ADRENERGIC RECEPTORS ARE FOUND WHERE?
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SYMPATHETIC NERVOUS SYSTEM (SNS)
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SNS NEUROTRANSMITTER
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NOREPI
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4 ADRENERGIC RECEPTORS IN SNS:
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ALPHA 1 AND 2
BETA 1 AND 2 |
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ALPHA 1
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EYES, BLOOD VESSELS, BLADDER, PENIS
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ALPHA 2
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PRESYNAPTIC NERVE TERMINALS
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BETA 1
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HEART KIDNEYS
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BETA 2
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LUNGS, SKELETAL MUSCLES, BRONCHI, UTERUS, LIVER
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WHY WOULD WE USE SYMPATHETIC DRUGS?
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PROVIDING EXTRA ADRENERGIC STIMULATION OR BLOCKING NORMAL ANS (AUTONOMIC) FUNCTIONING.
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WHAT MIMICS NOREPI?
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ADRENERGICS
SYMPATHOMIMETICS ADRENERGIC AGONIST (STIMULATES) |
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DEFINE DIRECT ACTING (AS IN DIRECT ACTING WITH ADRENERGIC RECEPTORS)
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DIRECTLY STIMULATING ADRENERGIC RECEPTORS (PICK AND CHOOSE)
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DEFINE: INDIRECT ACTING
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JUST STIMULATING THE RELEASE OF NOREPI FROM NERVE ENDINGS INTO SYNAPSE (NO SELECTION GOING ON. ALL ADRENERGIC RECEPTOR SITES ARE STIMULATED)
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DEFINE DUAL ACTING:
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STIMULATING BOTH ADRENERGIC RECEPTOR SITES (ENHANCING FIGHT OR FLIGHT MODES) AND THE RELEASE OF NOREPI
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