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5 Cards in this Set
- Front
- Back
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H1 antagonists, first generation
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Azatadine
Brompheniramine Chlorpheniramine Clemastine Cyprohepadine Dexchlorpheniramine Diphenhydramine Hydroxyzine Phenindamine Promethazine |
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H1 antagonists, second generation
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Fexofenadine
Cetirizine Lovocetirizine Loratadine (only one no scrip) Desloratadine Azelastine |
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H1 antagonists, effects on
Peripheral system CNS system Muscarinic cholenergic receptors |
peripheral: reduces local flushing, edema, itching, pain, and inhibits mucous production
CNS: therapeutic levels = depression: slows reaction time, drowsiness, lowers alertness. Overdose = opposite effect (especially in kids) Musc Chol: helps with motion sickness, nausea, vomiting, but also creates dry mouth & constipation |
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Adverse effects of H1 antagonists
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Sedation of CNS (confusion, fatigue, dizziness, tremors, convulsions) especially in elderly. give with meals to help with this
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Intranasal preparations for allergic rhinitis
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Azelastine (blocks both production and receptors of histamine)
Leukotriene antagonists Montelukast |
