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13 Cards in this Set

  • Front
  • Back
Describe MS
chronic, progressive, degnerative disorder of the CNS characterized by disseminated demyelination of nerve fibers of the brain and spinal cord
How does MS progress?
slowly, some patients even have remissions and exasserbations
What are the general manifestations of MS?
depends on where the plaques are in the CNS

motor, sensory, cerebellar and emotional problems
What in particular are some of the motor manifestations of MS?
weakness or paralysis of limbs, trunk or head

diplopia

scanning speech

spasticity of muscles
What are some of the sensory manifestations of MS?
numbness and tingling and other paresthesias

patchy blindness (scotomas)

blurred vision

vertigo

tinnitus

decreased hearing

chronic neuropathic pain
What are the cerebellar manifestations of MS?
nystagmus, ataia, dysarthria, dysphagia
What are the categories of drugs that are used for MS?
corticosteroids
immunomodulators
immunosuppressants
cholinergics
anticholinergics
muscle relaxants
cns stimulants
antiviral/antiparkinsonian
What symptoms are relieved from corticosteroids used for treatment of MS?
exacerbations

-watch for weight gain, edema, euphoria
Give an example of an immunomodulator used for treatment of MS.
b-interferon

se: flu like symptoms, local skin reactions, depression, monitor CBC, blood chem, liver function test q 3 months
What are the name of the immunosuppresant drugs that are used to treat MS?
Imuran
Cytoxan
What is the most common type of MS? Describe it.
Relapsing-remitting...clearly defined relapses with full recovery or sequelae and residual deficit on recovery
How is MS diagnosed?
No definitive dx test

history, manifestations,MRI for lesions
What are the non pharmacological treatments for MS?
diet (balanced and high in protein)

vitamins

rehab