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19 Cards in this Set

  • Front
  • Back
Inactivity effects on lipid panel?
Decreases HDL
ETOH effects on lipid panel?
Increases triglycerides
increases HDL
increases LDL
DM effects on lipid panel?
Increases triglycerides
increases TC
lowers HDL
Hypothyroidism effects on lipid panel?
Increases Triglycerides
Increases TC
Higher dose thiazide diuretics effects on lipid panel?
Increases TC
Increases LDL
Increases triglycerides
Chronic renal insufficiency effects on lipid panel?
Increases TC
Increases triglycerides
1 lb of fat =___ stored calories
3500 cal stored calories
How can you decrease LDL?
Diet
Increase plant sterols, stanols and fiber
Effects of exercise on HDLs?
Increases HDLs due to decreased insulin resistance
Labs with antilipidemic drugs?
Check LFTs and CPKs on baseline and 8 weeks after starting. Resins don't have to be checked. Not systemically absorbed, but separate from other drugs by 2 hrs
Keep triglycerides?
Under 150
Keep LDL?
below 100
below 70 with RF
Keep TC?
Under 150
HMG CoA reductase inhibitor (statins) effects lipid panel by?
Examples?
decreases LDL
decreases TG
increases HDL
Simvistatin
Resins effects lipid panel by?
Examples?
decrease LDL
increases HDL
Questran
Colestipol
separate other meds by 2 hrs
Niacin effects lipid panel by?
decreases LDL
effective against lipoprotien a
decreases TG
increases HDL

flushing, hyperglycemia
Fibric acid derivatives affect lipid panel by?
Examples?
Increase HDL
Decreases TG and LDL
Gemfibrozil (lopid)
Fenobibrate (Tricor)
can have rhabdo if taken with statins
Zetia (Ezetimibe) affects lipid panel by?
Examples?
Minimal effect on TG
decreases LDL
Increases HDL
adjunctive therapy
Zetia + simvastatin =vytorin
Increased rhabdo risk with statins when?
higher statin dose
in combo with fibrate
in renal impairment
mult comorbidities
low body wt
advanced age