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16 Cards in this Set
- Front
- Back
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Penicillin G?
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Streptococcus pneumoniae, however resistant strains are common
PCN V is an oral form of PCN and is commonly used for strep pharyngitis caused by Group A beta hemolytic strep, since it can be taken orallyStaphylococcus |
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Penicillinase resistant Pcns?
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useful against beta lactamase an enzyme that destroys beta lactam rings producing Staphylococcus aureus
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Anti Pseudomonal Pcns?
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including the carboxypenicillins
ureidopenicillins monobactams offers an even wider coverage against gram negative bac4teria including Pseudomonas aeruginosa |
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Cephalosporins?
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widely used gruop of a/b that have a beta lactam ring, are resistant to positive and gram negative bacteria
though many bacteria produce cephalosporinases, making the resistant to many of these drugs |
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Aminopenicillins?
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Have a broader spectrum then PCN G, hitting more gram neg organisms
still inhibited by pencillinase Escherichia ecoli and other enterics (proteus, salmonella, shigella) One of the few drugs that are effective agains gram positive enteroccus |
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Examples of Aminopenicillins?
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Ampicillin
Amoxicillin |
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Amoxicillin outpt therapy?
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More effectively absorbed orally so will requently use it for out patient tx of bronchitis, otitis media and sinusitis
DOC for infec caused by Listeria |
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Why is Ampicillin is commonly used with Aminoglycosides?
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Ampicillin IV ia commonly used with other A/B such as the aminoglycosides (gentamicin) for broad gram negative coverage
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Why is Amp-gent commonly used?
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pts with serious UTIs are often infected with a gram negative enteric or enterococcus. Amp gent offers broad empiric coverage until cult. reveals the exact organism responsible
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Ex of Penicillinase resistant Pcns?
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Nasty Ox w/ beta lactamase
Nafcillin Oxacillin Methicillin |
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What Penicillinase resistant Pcns
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Can kill Staph aureus
Naficillin is the DOC for serious staph aureus infections such as cellulitis, endocarditis and sepsis |
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Methicillin is not used anymore b/c of its occurence with ?
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Interstitial nephritis
It's not used iin the US anymore |
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How would you tx a pt with an infected skin wound?
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CLOX
Cloxacillin and dicloxacillin w/ cellulitis and impetigo, the pt most likely is infected with staph aureus or group a beta hemolytic strep. PCN G, V, or ampicillin would not cover penicillinase producing staph aureus. Use penicillinase resistant agents. |
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Cloxacillin and dicloxacillin
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These drugs are not good against gram negative organisms. Tehy are used for gram positive bacteria esp those that produce penicillinase (staph aureus)
Not good for MRSA |
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Gram positive bacteria?
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Streptococcus
Staphylococcus Bacillus Clostridium spore forming rod) Corynebacterium Literia(non spore forming rods) |
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Gram negative bacteria?
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Neisseria
the enterics\ Haemophilus Bordertella Legionella Yersinia Franciesalla Brucella Pasteruella Chlamydia Ricdettsia Spirochetes |
