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123 Cards in this Set

  • Front
  • Back
What are some common causes of IgE-mediated anaphylaxis?
foods
insect venoms
latex
medications
immunotherapy (allergy shots)
What type of hypersensitivity reaction is allergic rhinitis or asthma?
type I
What type of hypersensitivity reaction is a hemolytic transfusion reaction?
type II (cytotoxic/cytolytic)
What type of hypersensitivity reaction is Goodpasture syndrome?
type II (cytotoxic/cytolytic)
What type of hypersensitivity reaction is lupus, RA, and type 1 diabetes?
type III (immune-complex)
What type of hypersensitivity reaction is contact dermatitis?
type IV (delayed hypersensitivity)
What type of hypersensitivity reaction is TB?
type IV (delayed hypersensitivity)
What type of hypersensitivity reaction is transplant rejection?
type IV (delayed hypersensitivity)
Benadryl, Claritin, and Zyrtec are examples of what type of drug used to treat allergic reactions?
antihistamine
Sudafed and Neo-Synephrine are examples of what type of drug used to treat allergic reactions?
decongestant
Flonase is an example of what type of drug used to treat allergic reactions?
corticosteroid (nasal spray)
Calamine lotion, coal tar solutions, and camphor are examples of what type of drug used to treat allergic reactions?
antipruritic
Cromolyn is an example of what type of drug used to treat allergic reactions?
mast cell-stabilizing
Singulair is an example of what type of drug used to treat allergic reactions?
leukotriene receptor antagonist
the recommended treatment for control of allergic symptoms when the allergen cannot be avoided and drug therapy is not effective
immunotherapy
What type of allergy cannot be safely treated with immunotherapy?
food allergies
Name some foods that cause an allergic reaction in people who are allergic to latex.
bananas
avocados
kiwi fruit
tomatoes
water chestnuts
guava
hazelnuts
potatoes
peaches
grapes
apricots
What is the greatest risk factor for developing a latex allergy?
long-term multiple exposures to latex products
What is the primary trigger of MCS (multiple chemical sensitivites)?
odor

(gas exhaust, perfume, cigarette smoke, plastic, pesticides, etc.)
How is MCS (multiple chemical sensitivities) treated?
by avoiding the chemicals that trigger the symptoms
Certain HLA types are associated with what 3 autoimmune diseases?
ankylosing spondylitis
lupus
diabetes
Name some causes of secondary immunodeficiency disorders.
Drugs (chemo, corticosteroids) - this is the MOST COMMON cause**
Age
Malnutrition
Diseases (AIDS, cirrhosis, diabetes, lupus, burns)
Therapies (radiation, surgery)
Stress
In most transplantation situations, the biggest concern is the host's rejection of the graft. However, in _____________, the graft rejects the host or recipient tissue.

How is this treated?
graft-vs-host disease

usually, the organ must be removed. no meds can reverse this...
Transplant rejection can be prevented by closely matching _____, ______, and ______ between donor and recipient.
ABO
Rh
HLA
rejection that occurs minutes to hours after transplantation

no treatment for this but to remove the organ
hyperacute rejection
rejection that occurs days to months after transplantation

this is treated by changing the patient's immunosuppressive drug therapy
acute rejection
rejection that occurs months to years after transplantation and is irreversible

is typically a result of repeated bouts of acute rejection
chronic rejection
group of immunosupressive drugs that includes tacrolimus (Prograf) and cyclosporine (Sandimmune)

*most effective immunosuppressants available
calcineurin inhibitors
immunosupressive agent used in renal transplant recipients

*type of cytotoxic drug
sirolimus (Rapamune)
type of cytotoxic drug that has been shown to decrease the incidence of late graft loss

*AE = GI toxicities (N/V/D)
mycophenolate mofetil (CellCept)
immunosuppressive drug used to prevent and treat acute transplant rejection
monoclonal antibodies (Muromonab-CD3)
type of immunosupressive drug used to severely immunosupress a patient immediately after transplantation to prevent early rejection

also used to treat acute rejection
polyclonal antibodies (Atgam)
Phenergan, Thorazine, and Pepcid are examples of what type of drug used to treat N/V?
antihistamine

*these drugs block acid secretion
Scopolamine is an example of what type of drug used to treat N/V?
anticholinergic

*these drugs dry up secretions
Reglan is an example of what type of drug used to treat N/V?
benzamide

*these drugs speed up gastric emptying
Prilosec is an example of what type of drug used to treat N/V?
proton pump inhibitor

*these drugs block acid production
Tums and Rolaids are examples of what type of drug used to treat N/V?
antacid

*these drugs neutralize stomach acid
What type of meal should a patient with N/V eat when tolerated?
high carb, low fat

*fat slows peristalsis
What types of things are risk factors for or can contribute to a patient developing GERD?
hiatal hernia
foods (caffeine, chocolate, fatty foods)
alcohol
smoking
obesity
What are some possible complications of GERD?
erosive esophagitis
Barrett's esophagus (precancerous lesions)
What are some things you should teach your patient with GERD to do?
Stop drinking alcohol.
Stop smoking.
Eat a high-carb, low-fat diet.
Avoid lying down right after eating.
Treat with PPIs, H2 antagonists, and antacids.
If lifestyle modification cannot control the patient's GERD, what surgery can be done?
Nissen fundoplication - part of the fundus of the stomach is wrapped around the lower portion of the esophagus to reinforce and repair it
inflammation of the gastric mucosa that occurs as a result of a breakdown in the normal gastric mucosal barrier
gastritis
What are some risk factors for developing gastritis?
drugs (NSAIDs, aspirin)
diet (alcohol, spicy foods)
H. pylori
smoking
What would you as the nurse do to treat a patient with acute gastritis?
Eliminate the cause.
Treat N/V symptoms with antiemetics.
Maintain NPO status and advance diet slowly.
Give IVF to prevent dehydration.
Assess emesis for s/s of bleeding.
With what GI disorder may a patient need to receive vitamin B12 injections?
gastritis
Are antibiotics used to treat diarrhea?
RARELY! Using them could cause a c-diff infection!
What two electrolytes can get out of balance in a patient with diarrhea?
K+
Mg++
Chronic diarrhea causes what acid-base imbalance?
metabolic acidosis
Lomotil, Immodium, and Pepto-Bismol are three drugs that are used to treat _________.
diarrhea
What are two important things you as the nurse can do for someone with fecal incontinence?
Implement a bowel training program.

Maintain skin integrity, especially in the bedridden and older adult patient.
Name some common causes of constipation.
narcotics
low fiber diet
sedentary lifestyle
dehydration
depression
stress
What should the nurse teach her patient with constipation?
Increase dietary fiber.
Drink enough fluids.
Exercise regularly.
Establish a regular time to defecate.
Who is responsible for removing an impaction?
the RN!!
What are the clinical manifestations of appendicitis?
rebound tenderness
RLQ pain
anorexia
N/V
Palpation of the left lower quadrant which causes pain to be felt in the right lower quadrant is known as ___________ and is found in what GI disorder?
Rovsing's sign

appendicitis
What diagnostic studies are done in a patient with appendicitis?
CBC - to determine if WBC is elevated

CT scan or ultrasound - to see if appendix is enlarged
What are the complications associated with appendicitis if it is not treated?
rupture and peritonitis
What are the s/s of peritonitis?
tachycardia
tachypnea
pallor
abdominal distention/pain
restlessness
fever/chills
Should you put heat or ice on an inflammed appendix?
ice

**NEVER USE HEAT - may cause appendix to rupture
What can cause a nonmechanical intestinal obstruction?
anesthesia
head injury
Prior to an intestinal obstruction, you will hear __________. After the obstruction, you will hear ______________.
hyperactive bowel sounds

NOTHING
What are the clinical manifestations of intestinal obstruction?
N/V
abdominal pain/ distention
inability to pass flatus
hypoactive/absent bowel sounds
Why is an NG tube used in a patient with intestinal obstruction?
to decompress (suction) the stomach since nothing is getting through
What are the clinical manifestations of diverticulitis?
** Most have no symptoms!

Can cause:

abdominal pain over involved area of colon
change in bowel habits
possible fever or elevated WBC (esp. in elderly)
What should the nurse do for a patient with diverticulitis?
**To prevent it in the first place, teach pt. to eat more fiber and less red meat/fat and to exercise more.

During acute phase:

Keep patient NPO and encourage bedrest.
Monitor WBC.
Monitor for peritonitis.
Once patient is no longer NPO, give them a high-fiber diet with NO NUTS!
What are some possible complications of diverticular disease?
peritonitis
bowel obstruction
bleeding
What are the clinical manifestations of hemorrhoids?
bleeding
pruritus
prolapse
pain
Should a patient with hemorrhoids use doughnut pillows to sit on?
NO!
What should the nurse teach a patient with hemorrhoids?
Use stool softeners to prevent constipation.
Avoid prolonged standing or sitting.
Use sitz baths to reduce discomfort and swelling.
yellowish discoloration of body tissues that results from an alteration in normal bilirubin metabolism or flow of bile into the hepatic or biliary duct systems
jaundice
What is the route of transmission for hepatitis A?
fecal-oral
What is the route of transmission for hepatitis B?
blood/body fluids
What is the route of transmission for hepatitis C?
blood/body fluids
What is the route of transmission for hepatitis D?
blood/body fluids

*can only cause infection when hep B is present
hepatitis without jaundice
anicteric jaundice
hepatitis with jaundice
icteric jaundice
severe impairment or necrosis of liver cells caused by acute viral hepatitis
fulminant hepatitis
What should the nurse do for a patient with acute viral hepatitis?
Encourage the patient to rest.
Promote nutrition.
Treat N/V and pain.
Teach patient to avoid alcohol and liver toxic meds.
What is the goal of treatment for chronic hepatitis?
Decrease viral load and give meds that interfere with viral replication.
What drugs are used to treat acute viral hepatitis?
there aren't any!!
How can hepatitis be prevented?
handwashing
personal hygiene
environmental sanitation
screening of food handlers
active immunizations to ppl over age 2
What causes postnecrotic cirrhosis?
hepatitis
What causes biliary cirrhosis?
chronic biliary obstruction and infection
What causes cardiac cirrhosis?
longstanding right heart failure
What are some EARLY clinical manifestations of cirrhosis?
anorexia
dyspepsia
flatulence
N/V/D/C
What are some LATE clinical manifestations of cirrhosis?
jaundice
skin lesions (spider angiomas)
hematologic problems (thrombocytopenia, leukopenia, anemia)
endocrine problems
peripheral neuropathy
What are some complications of cirrhosis?
portal hypertension
esophageal and gastric varices
peripheral edema
ascites
hepatic encephalopathy
hepatorenal syndrome
How is ascites treated?
Limit patient's sodium intake.
Paracentesis - manually drain fluid out of abdomen
What is the goal in treating hepatic encephalopathy?
reduce ammonia (using Lactulose)
What are the clinical manifestations of cholecystitis?
RUQ pain (may radiate to right scapula and shoulder)
fever
jaundice
N/V
What are the clinical manifestations of acute pancreatitis?
midepigastric pain that may radiate to the back
N/V
dehydration
abdominal distention
What are the clinical manifestations of peptic ulcer disease (PUD)?
burning epigastric pain
What are the risk factors for developing peptic ulcer disease (PUD)?
H. pylori
caffeine
coffee
aspirin
smoking
alcohol
How long should you keep a patient NPO after an endoscopy?
until his gag reflex returns
For gastric lavage, should you use normal saline that is room-temp or refrigerated?
room-temp!
Why should you keep the vent lumen of the NG tube positioned above midline?
to prevent gravity drainage of gastric contents through the port
What drug therapy is used to treat peptic ulcer disease (H. pylori)?
two antibiotics and a PPI

*H2 antagonists are used to promote ulcer healing after triple therapy is finished
What are some potential complications of peptic ulcer disease?
GI bleeding - b/c region is very vascular
perforation
gastric outlet obstruction - ulcers can cause swelling and obstruct pyloric sphincter
dumping syndrome after GI surgery
What should you teach your patient to do in order to prevent dumping syndrome after GI surgery?
Lie down after meals to prevent rapid stomach emptying.

Limit fluid intake with meals.
What is the drug of choice to treat pain caused by acute pancreatitis?
morphine
Why is dehydration associated with acute pancreatitis?
nausea/vomiting

pancreatic inflammation and "third spacing"
What are some risk factors for developing acute pancreatitis?
alcohol abuse
cholelithiasis
age over 55 yrs
obesity
What blood work and tests are diagnostic for acute pancreatitis?
elevated serum amylase and possibly lipase

CT scan - to look at size of pancreas and identify any necrosis
bluish color around bellybutton

*this is associated with what GI disease?
Cullen's sign

acute pancreatitis
blue/red or green/brown flanks

*this is associated with what GI disease?
Turner's sign

acute pancreatitis
How should you position a patient with acute pancreatitis to promote comfort?
side lying with hips and knees flexed
Effective treatment for acute pancreatitis should lead to:
decreased abdominal distention
What are some clinical manifestations of early alcohol withdrawal?
agitation
anxiety
tremors
irritability
diaphoresis
How is alcohol withdrawal treated?
Ativan
What are the clinical manifestations of delirium tremors (most severe form of alcohol withdrawal)?
high BP
confusion
hallucinations
delusions
seizures
fever
tremors
diaphoresis
What type of long-term diet should a patient recovering from acute pancreatitis eat?
high carbs

*Avoid spicy foods, caffeine, and alcohol
What are the clinical manifestations of colon cancer?
change in bowel habits
blood in stool
abdominal distention/pain
What are some risk factors for developing colon cancer?
age > 50 yrs
high fat diet
family hx
obesity
sedentary lifestyle
hx of ulcerative colitis
hx of polyps
Why are prophylactic antibiotics taken before a colonoscopy?
to decrease bacteria in intestine and to decrease risk of post op wound infection
What position should you place a patient in after colon resection?
Fowler's
superficial separation of wound edges
dehiscence
What may precede wound evisceration?
excessive drainage from incision
What should you do if wound evisceration occurs?
cover the wound with sterile towels moistened with sterile saline
If this is elevated, it may indicate that colon cancer is coming back.
CEA
What color should an ostomy stoma be?
pink
What should you wash a stoma with?
mild soap
How often should a colostomy pouch be changed?
every 5 days and as needed