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227 Cards in this Set

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How many older Americans have dementia?

15%

How many dementia patients have Alzheimers?

60 to 80% have alzheimers

6 progressive neurodegenerative diseases that fall under dementia umbrella:

Alzheimer's disease


Dementia with Lewy bodies


Front temporal degeneration


Down syndrome


Amyotrophic lateral sclerosis


Parkinson disease


Huntington's disease

9 Causes of dementia:

1. Vascular disease


2. Toxic/metabolic/ nutritional disease


3. Neurodegenerative disorders


4. Immunologic (ie AIDS)


5. Systemic disease


6. Trauma


7. Tumors


8. Ventricular disorder


9. Drugs



3 Systemic diseases that can cause dementia:

1. uremic/hepatic encephalopathy


2. dialysis dementia


3. wilsons

What is hydrocephalus?

Increased inter cranial pressures from anatomy of the brain?

9 Drugs that can cause dementia:

1. Anticholinergics


2. Phenytoins


3. Opioids


4. Hypnotic


5. Tranquilizers


6. Antiparkinsonian drugs


7. Cardiac: Digoxin methylaopa


8. Cocaine


9. Heroin

60-80% of dementias

alzheimers disease

20% of dementias

vascular dementia

10% of dementias

dementia w/ lewy bodies

What to rule out in abrupt dementia?

-Infection


-Fluid/electrolyte imbalance



What 3 labs do you need to run for dementia diagnosis?

1. Complete blood count (w/ WBC)


2. Hemoglobin & Hemocrit


3. Vitamin B12


4. Neurosyphilis


5. Liver function tests


6. Sodium levels


7. BUN & Creatin (renal disfunction)



3 groups with higher alzheimer's rates:

-African American


-Hispanic


-Women

Type of dementia men are more likely to have?

-Vascular dementia (strokes)



4 Brain abnormalities in Alzheimers:

1. Neurofibrillary tangles


2. Amyloid plaque


3. loss of neuron connection


4. Neuron death (usually the tail dies)

Clinical manifestations of Alzheimers

Memory loss


Difficulty performing familiar task


Problems with language


Dis-orientation


Poor judgment


Problem with abstract thinking


Misplacing things


Changes in mood or behavior


Changes in personality


Loss of initiative

Subjective data to check for Alzheimer's Nursing Assessment:

Subjective Data:


Past medical history


Repeated head trauma


StrokeExposures to heavy metals


CNS infections


Family HX of dementia


Functional health patterns

Objective data you might gather for alzheimer's patients.

Objective Data:


General: Disheveled appearance, agitation


Neuro: Loss of recent memory, Disorientation, flat affect, impaired abstract cognition and judgment.

Medication given for memory/cognition in alzheimers:

1. Doneprezil (Aricept)

Medication given for Depression in alzheimers:

SSRIs


sertraline(Zoloft)


citalopram(Celexa)


fluoxetine(Prozac)


mirtazapine(Remeron)


trazodone(Desyrel)

Medication given for Behavioral in alzheimers:

Antipsychotics


haloperidol(Haldol)


risperidone(Risperdal)


olanzapine(Zyprexa)


quetiapine(Seroquel)

Medication given for sleep in Alzheimers

Zolpidem(Ambient)


quetiapine(Seroquel)


trazodone(Desyrel)

Define delirium

State of temporary but acute mental confusion

Who is at risk for delirium?

-anyone with cognitive disfunction


-age over 70


-Psycho active anticholinergic med


-Hx stroke/epilepsy


-Hx depression


-Illicit drug use


-Hypernatremia, Hyperglycemia, Hyperthermia


-BUN/Creatinine ratio greater than 18


-Renal failure


-Liver disease


-CHF


-Shock (septic/cardiogenic)


-HIV


-Tube feedings


-Rectal/bladder catheters


-Central venous cath


-Malnutrition


-ETOH


-Sensory impairment

Etiology of Delirium:

DDELIRIUM


D: dementia


D: drugs (ploy-charm)


E: electrolyte imbalance


L: lack of drugs


I: Infection


R: reduced sensory input


I: Intercranial pressure


U: urinary/fecal retention


M: myocardial/pulmonary (hypoxia)

Diagnostic study for Delirium

Serum electrolytes


Blood urea nitrogen level


Creatinine level


Complete blood count (CBC)


Drug and alcohol levels


Electrocardiogram (ECG)


Urine analysis


Liver and thyroid function tests


Oxygen saturation level


Lumbar puncture

What does erythropoietin do?

1. production of RBC


2. releases hormones that influence stem cell that make WBC & platelets

What will a nurse do with an anemic patient

-monitor safety


-address fatigue

what are you concerned for with a patient with low platelets?

bleeds

what is the issue with renal failure based anemia

not enough red blood cells

Kidney function: activate vitamin D & absorb calcium from GI tract- what is a nurse thinking with renal failure? (3)

safetypreventative measures to prevent breaking bones & bone lossmonitor cardiac w/ telemetry

7 issues with aging renal system

Decreased kidney size.


Decreased renal blood flow.


Decreased nephron function.


Decreased GFR.


Decreased estrogen in females.


Decrease muscle support.


Increase prostate size. (with men)

4 functions of renal system

1. regulate volume and composition of extracellular fluid


2. regulate blood pressure


3. make erythropoietin


4. activate vitamin D and promote Ca absorption

Normal creatinine clearance

80 to 135 ml/min

What is KUB?

abdominal X ray can show size of kidneys, bladder,m malignancies

Dye Studies

best indication of vasculature of kidneys (NOTE- dye can actually worsen renal function)

Renal Biopsy

can give us an idea about nephrons and how they are working

ESRD

15ml/min

Normal urine color


Abnormal urine color

norm: amber yellow


abnormal: dark, cloudy



Thoughts on clear urine?

Kidney may be working overtime

Normal/abnormal urine smell

Norm- aromatic


Abnormal- unpleasant

Normal clarity of urine/ Abnormal clarity of urine

Normal: clear


Abnormal: cloudy

Normal / Abnormal Protein

normal: 0 to trace


abnormal: persistent

Normal / Abnormal pH

Normal 4.0 to 8.0


Abnormal greater than 8.0

Normal / Abnormal glucose

norm: none


abnormal: present

Normal / Abnormal ketones

norm: none


abnorm: present

Normal / Abnormal bilirubin

norm: none


abnorm: present

Normal / Abnormal Osmo

norm: 300- 1300


abnorm: less than 300, more than 1300

Normal / Abnormal RBC

norm: 0-4


abnorm: more than 4

Normal / Abnormal WBC

norm: 0-5


abnorm: greater than 5

oliguria

diminished amounts of urine at a given time

anuria

no urine (24 hour urine output is less than 100mls)




-only normal for patient on hemodialysisSe

Second most common bacterial disease

UTI

Most common bacterial infection in women

UTI

Upper urinary tract infection

pyelonephritis

Pyelonephritis

inflammation of renal parenchyma and collecting system.




sx= fever, chills, flank pain

Lower urinary tract infection

cystitis- inflammation of bladder wall

Urosepsis

systematic infection that oriented in urinary tract

Sx: flank pain, high white count, fever, fatigue, malaise, diaphoretic

Pyelonephritis

classic symptoms of UTI

-frequency


-urgency


-incontinence


-nocturia


-nocturnal enuresis

UTI sx in older adults

confusion


non localized abdominal discomfort

2 main steps of Diagnosing UTI

-urinalysis


-culture

Urosepsis

systemic infection from urologic source, can lead to septic shock and death

4 frequent organisms seen in UTI

-E coli


-proteus


-klebsiella


-enterobacter

vasicoureteral reflex

backward movement of urine from lower to upper urinary tract

3rd leading cause of renal failure

glomerulonephrities

hematuria, urinary exertion of RBC, WBC, yeast, proteinuria, elevated BUN and Creat are clinical manifestations of what?

Glomerulonephritis

First sign you will see in glomerulonephritis

Hematouria

Kidney biopsy is the best way to diagnose

Glomerulonephritis

Therapy for Glomerulonephritis includes

rest


sodium & fluid restriction


diuretics- challenge kidney


-antibiotics


-antihypertensive therepy


-restrict dietary protein

3 causes of acute renal failure

1. Pre renal


2. Intra renal


3. Post renal

Acute Pre renal Failure

-not enough blood filtering into urine


(decreased CO= decreased renal output)


-Heart failure, blood not moving, kidney not being professed


-MI, heart tissue death, dysrhthmias, heart not pumping well, other organs suffer including kind-renal artery thrombosis-

3 phases of acute renal failure

1. Oliguric phase: less than 400 ml/24 hrsdecrease in urine output, abnormal BUN and creatine


2. Diuretic Phase: 1-3 litres per day, abnormal labs


3. Recovery Phase: GFR increases, urine output



Tx for pre-renal acute renal failure

tx dehydration and bleeding

Leading causes of ESRD

-diabetes


-hypertension


-glomerularnephritis

Clinical manifestations of CKD

hypertension


heart failure


left ventricular hypertrophy


peripheral edema


dysrhythmias


uremic pericarditis

definitive diagnosis for CKD

Renal biopsy

Dementia breakdown: 15% of older Americans have dementia. What percent of those have Alzheimer's? What percent have Lewy Bodies? What percent have Vascular dementia?

60-80% Alzheimers


20% Vascular Dementia


10% Lewy Bodies



20% of dementia patients have

Lewy Bodies

10% of dementia patients have

vascular dementia

60 to 80% of dementia patients have

Alzheimers

examples of Dementia causes (name a few, there are a lot)

alzheimers


lewy bodies


front temporal degernareation


down syndrome


amyotrophic lateral sclerosis


parkinson disease


huntington's disease


vascular disease


toxic metabolic nutritional disease


immunologic


systemic disease


trauma


tumors


drugs


ventricular disorders

3 examples of vascular disease that cause dementia

1. vascular (multiinfract) dementia


2. subarachnoid hemorrhage


3. chronic subdural hematoma




VERY SPECIAL CHILDREN

6 examples of toxic, metabolic/nutritional disease that causes dementia

1. alcoholism


2. thiamine (B1) deficiency


3. colbalmin (B12) deficiency


4. folate deficiency


5. hyperthyroidism


6. hypothyroidism




A TIRED COP FED HIGH HYPOCRITES

8 examples of immunologic disease that causes dementia

1. MS


2. chronic fatigue syndrome


3. infections


4 AIDS


5 Meningitis


6. Encephalitis


7. Neurosyphilis


8. Lupus




MY CHILDREN IN AFRICA MADE ELEPHANTS NUSSLE LIONS

3 examples of systemic disease that cause dementia

-uremic/hepatic encephalopathy


-dialysis dementia


-wilsons

9 drugs that can cause dementia

-anticholinergics


-phenytoins


-opioids


-hypnotic


-tranquilizers


-antiparkinsonian drugs


-cardiac: digoxin methyldopa


-cocaine


-heroin

7 clinical manifestations of dementia

-mistaken for depression


-sadness


-fatigue


-apathy


-despair


-inactivity




I'M SAD, F.

4 ways to diagnose dementia

1. full medical neurologic and psychological history


2. labs


3. head CT


4. Head MRI

important labs for diagnosing dementia

-vitamin B12 levels


-neurosyphilis


-hematocrit


-hemoglobin


-CBC


-LFT


-Sodium levels


-BUN & Creatine



to find out if fluid is backing up into brain and building up ammonia AND CAUSING DEMENTIA, what kind of lab will you run?

=LFT


=BUN & Creatine

how many american's are effected by Alzheimers?

5.2 million

how many years do people typically live after alzheimer diagnosis

4 to 8 years



what ethnicities/ gender have highest rates of AD?

-African Americna


-Hispanics


-Women

what gender is most likely to develop vascular dementia?

men

causes of alzheimer's disease

-unknown


-genetic


-environmental


-brain abnormalities

name 4 possible environmental risk factors of AD

-diabetes


-HTN


-Smoking


-High cholesterol



example of mini mental exam

"If I were to say "No If's, And's, or Buts" what would that mean to you?

10 early warning signs of alzheimer's

1. memory loss


2. familiar task


3. language


4. disorientation to time and place


5. judgement


6. abstract thinking


7. misplacing things


8. mood or behavior


9. personality


10. initiative

mild symptoms of alzheimer's

-forgetfulness


-short term memory loss


-initiative loss


-small personality change


-abstract thinking


-slow loss of ability to plan or organize

a person who is struggling with solving simple math problems may be experiencing this level of alzheimer's symptoms (MILD, MODERATE, SEVERE)

Mild

Forgetting a person's name, recent events, or things.- May be experiencing this level of alzheimer's symptoms (MILD, MODERATE, SEVERE)

Mild

Moderate symptoms of alzheimer's disease

-memory loss & confusion are obvious


-increased trouble organizing, planning, following directions


-needs help getting dressed


-may start having incontinence


-trouble recognizing close family members or friends


-agitation, restlessness


-lack judgement, begins to wander and get lost


-trouble sleeping


-delusions, hallucinations, paranoia


-behavioral problems

This person with AD may need help getting dressed (MILD< MODERATE< SEVERE)

Moderate or severe

This person with AD may become incontinent (MILD< MODERATE< SEVERE)

Moderate or severe

This person with AD may have trouble recognizing family members or friends (MILD< MODERATE< SEVERE)

Moderate

This person with AD may have delusions, hallucinations, and paranoia (MILD< MODERATE< SEVERE)

Moderate

This person with AD may experience agitation and restlessness (MILD< MODERATE< SEVERE)

Moderate

This person with AD may have trouble sleeping (MILD< MODERATE< SEVERE)

Moderate

This person with AD may lack judgement, begin to wander, and get lost (MILD< MODERATE< SEVERE)

Moderate

Severe symptoms of AD

-severe impairment of all cognitive functions


-little memory, unable to process new info


-unable to perform self care


-requires help with ADL


-may lose ability to speak


-may not be able to understand speech


-may have trouble eating, swallowing


-may not be able to walk or sit up without help


-immobility


-incontinence

This person with AD may not be able to walk or sit up without help (MILD< MODERATE< SEVERE)

severe

This person with AD may have difficulty eating or swallowing (MILD< MODERATE< SEVERE)

Severe

This person with AD may not be able to speak or understand words (MILD< MODERATE< SEVERE)

severe

This person with AD may need help with daily needs and may be unable to perform self care activities (MILD< MODERATE< SEVERE)

severe

what are you looking for in a head CT for alzheimer's

cerebral cortex atrophy

what are you looking for in an MRI for alzheimer's

hippocampal atrophy

what could a PET scan show you in diagnosing AD

small vascular spaces

how to Alzheimer's meds (and SSRI's, Antipsychotics, and sleeping meds) effect bowels

CONSTIPATION OR LOOSE STOOL

what is delirium?

a state of temporary but acute mental confusion

is delirium dangerous

yes, it can be life threatening

is delirium preventable

yes, possibly

what population has the highest amount of delirium?

highest in hospitalized older adults

5 terms for delirium

-vague, off


-icu psychosis


-a little crazy today


-organic brain syndrome


-actue change in mental status


-toxic psychosis

what is the likelihood of developing delirium for NON ICU patients with 3 or more risk factors?

60%

a patient who is over 70, has hypernatremia, and a BUN/Creatinine ratio greater than 18 is at risk for what?

delirium

A patient with a central venous catheter, a bladder catheter, and CHF is at risk for what?

Delirium

A patient who is over 65, is female, and smokes may be at increased risk for

AD

CD2 DELIRIUM

Chronic stress


Dementia, dehydration


Drugs (poly pharm)


Electrolyte imbalance


Lack of drugs (pain, withdrawal)


Infection, injury, Immobility


Reduced Sensory Input


Intracranial pressure


Urinary retention/fecal impaction


Myocardial/pulmonary hypoxia)

precipitating factors of delirium

-age (65 or older)


-gender- male


-cognitive status


-environmental


-prolonged sleep deprivation


-functional status


-sensory


-decreased oral intake


-coexisting medical conditions


-severe acute/terminal illness


-chronic renal/liver disease


-hx of stroke


-neurologic disease


-infection/sepsis


-fracture/trauma

4 environmental factors that precipitate delirium

-admission to ICU


-use of physical restraints


-pain (esp untreated)


-emotional stress

how long does delirium develop?

over 2 to 3 day period



what are early manifestations of delirium?

-inabilty to concentrate


-irritability


-insomnia




-loss of appetite


-restless


-confusion




IC-IC-IRL-

what are later manifestations of delirium?

-Hallucinations


-Agitation


-Misperception


-Misinterpretation




(HAMM)

how long will delirium last?

1 to 7 days

what is the most frequent consequence after unscheduled surgery on older adults?

delirium

3 sudden and key distinctions between dementia and delirium- delirium exhibits-

-sudden cognitive impairment


-sudden disorientation


-sudden clouded sensorium

what meds will you check for when a patient is presenting with delirium

anticholinergics, pain meds

what laboratory tests might help you explore the cause of delirium

-serum electrolytes


-BUN


-creatinine


-CBC


-Drug & alcohol level


-ECG


-Urinalysis


-Liver & thyroid function tests


-Oxygen sat


-Lumbar puncture

5 meds given to patients with SEVERE delirium (increases risk for falls and injury, use w/ caution)

start low go slow


-haloperiodol


-risperidone


-olanzapine


-quetiapine


-short acting benzodiazepines (i.e. lorazepam)

note about lorazepam (ativan) in treating delirium

-usually we stay away from this, it amens agitation worse w/ dementia

normal function at PCT

REABSORB:


-electrolytes


-water


-glucose


-amino acids


-HC03




SECRETE:


H+


Creatinine



normal function of glomerulus

filtration

normal function at ascending loop of henle

REABSORBTION:


-Na


-H+

normal function at descending loop of Henle

REABSORBTION


-water




+Concentration of filtrate

normal function at distal tubule

SECRETION:


-K


-H+


-Ammonia




REABSORBTION:


-water (w/ ADH)




REGULATION:


-Ca


-PO4 (w/ PTH)


-Na


-K (w/ aldosterone)

what allows for reabsorption of water from distal tubules

ADH

what allows for regulation of PO4 at distal tubule?

PTH

what allows for regulation of K at distal tubule

Aldosterone

ADH works on what portions of the renal tubules?

-Collecting duct


-Distal tubule

what 3 things must you monitor when a person is having kidney problems?

-electrolytes (potassium, sodium, chloride, waste products BUN and creatinine


-Fluid status (daily weights, I& ), lungs)


-BP

when is renin released?

in response to:


- low flow/ decreased cardiac output


-decreased serum sodium/ increased urinary sodium



what is Epogen

synthetic hormone (Erythropoetin)

what happens to RBC in renal failure?

anemia, decrease in RBC, WBC, PLT

4 renal functions

1. fluid & electrolyte balance


2. Erythropoetin


3. Activate vitamin D & absorb calcium from GI tract


4. regulate blood pressure w/ renin angiotensin system

calcium plays a key role in what

muscle contraction, especially cardiac muscle

geriatric patients will see what changes to their renal function

-decreased kidney size


-decreased renal blood flow


-decreased nephron function


-decreased GFR


-decreased estrogen females


-decreased muscle support


-increased prostate size

how to diagnose renal issues (9)

-urinalysis


-urine culture


-creatinine clearance


-GFR


-Blood tests (5)


-KUB (abdominal X ray)


-Ultrasound


-CT scan


-Dye contrast study


-Biopsy


-Nuclear studies

what are the 5 general blood tests that can be done to diagnose renal disease

-BUN


-Creatinine


-Electrolytes: potassium, sodium, chloride


-CBC


-Calcium, phosphorus




BE-CCC

What electrolytes are we monitoring when we are worried about kidney function

potassium


sodium


chloride


calcium


phosphorus

what is a normal creatinine clearance

80 to 135 mL/min

what is the creatinine clearance with ESRD

15 mL/min

what is creatinine clearance

the volume of blood cleared of creatinine per unit of time. Usually a 24 urine collection/ kept on ice.

what are the benefits of dye studies in diagnosing renal issues

-best indication of vasculature of kidneys (BUT DYE CAN ACTUALLY WORSEN FUNCTION)

what are the benefits of KUB in diagnosing renal issues

KUB- abdominal Xray can show size of kidneys, bladder, malignancies

what can we observe from an ultrasound of the kidneys

vasculature of kidneys

Urinalysis: normal & abnormal- Color

normal: amber


abnormal: dark/cloudy

Urinalysis: normal & abnormal- odor

normal: aromatic


abnormal: unpleasant

Urinalysis: normal & abnormal- protein

normal: 0-trace


abnormal: persistant

Urinalysis: normal & abnormal- glucose

normal: 0


abnormal: present

Urinalysis: normal & abnormal- ketones

normal: 0


abnormal: present

Urinalysis: normal & abnormal- bilirubin

normal: 0


abnormal: present

Urinalysis: normal & abnormal- specific gravity

normal: 1.003-1.030


abnormal: low or high

Urinalysis: normal & abnormal- osmo

normal: 300-1300


abnormal: <300/>1300

Urinalysis: normal & abnormal- pH

normal: 4.0-8.0


abnormal: >8.0

RBC

normal: 0-4


abnormal: >4

WBC

normal: 0-5


abnormal: >5

Bacteria

normal: none


abnormal: present

Keytones in urine may indicate

-DM


-starvation


-dehydration


-vomiting


-severe diarrhea

Bilirubin in urine may indicate

liver disorder

abnormal osmolarity variance in urine (<300/ >1300) may indicate

tubular dysfunction


-kidney has lost ability to concentrate urine


-over diluted urine

abnormal levels of RBC in urine (>4) indicate

-trauma


-UTI


-cancer


-glomerulonephritism


-TB

glucose in urine may indicate

DM


Pituitary disorder

persistant protein in urine may indicate

actor or chronic renal disease (involving glomeruli)- check medications

Low/high specific gravity in urine may indicate

low: too dilute


high: dehydration

define oliguria

diminished amounts of urine at a given time

define anuria

no urine (24 hour output less than 100mL)

when is a 24 hour output of urine less than 100mL normal?

when a patient is on hemodialysis

second most common bacterial disease

UTI

most common bacterial infection in women

UTI

most common pathogen

escheria coli

counts of bacteria 10tothe5th CFU's/mL

significant UTI

Counts as low as 10 to the 2 CFU/mL in a person w/ UTI symptoms

UTI

what parts of the body are affected in Upper UTI

Renal parenchyma


pelvis


ureters

example of upper UTI

pyelonephritis: inflammation of renal parenchyma and collecting system

example of lower UTI

cystitis- inflammation of bladder walle

what is urosepsis

systemic infection that originated in urinary tract

4 classifications of UTI

-initial infection


-recurrent infection


-resistant organism


-chronic infection



define nocturia

waking up more than 2x per night to void

define urinary frequency

abnormally frequent more than every 2 hours

nocturnal enuresis

complaint of loss of urine during sleep

s/sx of UTI in older adults

-often absent


-non localized abdominal discomfort rather than dysuria


-cognitive impairment


-less likely to have a fever

are older adults more or less likely to have a fever with UTI

less likely

4 groups at risk for UTI

-debilitated persons


-older adults


-underlying disease (HIV, diabetes)


-taking immunosuppressive drug or corticosteroids

how much fluid per pound should someone drink?

15 mL/lb

3 meds for complicated UTI

-levofloxacin


-ciprofloxacin


-fluoroquinolones



what is acute pyelonephritis

inflammation of renal parenchyma & collecting system, most commonly cause by bacteria (but can also be caused by fungi, virus, protozoa)

4 suspects for acute pyelonephritis infection

-escheria coli


-proteus


-Klebsiella


-Enterobacter




(KEEP)

A preexisting factor is usually present when a acute pyelonephritis occurs. 2 factors are:

-vesicoureteral reflux (backward movement of urine)


-dysfunction of lower urinary tract (obstruction from BPH, stricture, urinary stone)

recurrent acute pyelonephritis infections lead to

scarred kidney, chronic pyelonephritis

4 symptoms of acute pyelonephritis (sx last a few days and subside, bacteriuria & pyuria still persist)

-mild fatigue


-chills


-fever


-vomiting


-malaise


-flank pain


-lower UTI sx


-costovertebral tenderness on affected side

4 laboratory tests for acute pyelonephritis

-urinalysis


-urine culture & sensitivity


-CBC w/ differential


-blood culture (if bacteremia is suspected)

you assess a patient with fever, hematuria, foul smelling urine, tender enlarged kidney, leukocytosis, positive for bacteria in urine, WBC, RBC, pyuria, ultrasound, CT scan, IVP- what do you think they have?

acute pyelonephritis

what is pyuria

puss in urine

What is glomerulonephritis

immunologic process involving the urinary tract (predominantly renal glomerulus) classified by extent of damage, initial cause of disorder, and extent of change

what is the third leading cause of renal failure

glomerulonephritis

how do you classify glomerulonephritis

-extent of damage (acute/chronic)


-Initial cause of disorder (autoimmune, infection, other disease process)


-extent of changes

what are the 3 leading causes of renal failure

1. Diabetes


2. HTN


3. Glomerulonephritis

What is the first sign you MIGHT see in glomerulonephritis?

hematuria, if you see anything at all.

4 clinical manifestations of glomerulonephritis

-hematuria


-urinary excretion of RBC, WBC, cast


-proteinuria


-elevated BUN and Creatinine

4 diagnostic tests for glomerulonephritis

-urinalysis


-CBC w/ WBC differential


-BUN, Creat, Albuming


-Renal biopsy

3 types of acute renal failure

-pre renal- related to CO or vasculature


-intra-renal- drugs, x-ray dye, lupus, toxemia of pregnancy, ATN acute tubular necrosis


-post renal- bladder/prostate cancer, spinal cord disease, neuromuscular disorder

3 phases of acute renal failure

-oliguric phase: <400 mL/ 24hr, increase in BUN and creatine




-diuretic phase: 1-3 L/day & abnormal labs




-recovery phase: GFR increases, BUN/Cr decreases

Oliguric phase of acute renal failure

<400 mL/24 hr, elevated BUN and Creatine



Diuretic Phase of acute renal failure

1-3 L urine/day & abnormal labs

Recovery phase of acute renal failure

GFR increases, BUN/CR decrease- labs going back to normal

How to tx pre renal acute renal failure

tx dehydration, bleeding