Nuclear Pharmacy - Pet Scans

Front 1

What is the advantage to doing a whole body scan with PET/CT?

Back 1

it can be done in 10 min
what kind of compounds are used?

Hint 1

carbon 11

Front 2

PET RP's have what in common?

Back 2

They are short lived and are radioactive isotopes of elements encountered in nature and all produced in cyclotron.
Give 4 examples?

Hint 2

1. O15 (t1/2= 2 min)
2. C11 (t1/2 = 20 min)
3.N13 (t1/2 = 10 min)
4. F18 (t1/2 = 110 min)

Front 3

Why is Rubidiium 82 good for cardiac perfusion studies?

Back 3

it is similar to potassium and can enter heart muscle the same way

Front 4

Why does the Rubidium generator need to be on site for cardiac imaging and how does it work?

Back 4

It is generated from Sr82 of which Rb is the daughter and it has a half life of 1.27 min. so the patient has to be hooked up via IV to do study.
What is the disadvantage/advantage of this?

Hint 4

Cannot do physical stress but can do stress rest back to back do to short half life

Front 5

When considering shielding for PET scanners what is the difference from Tc?

Back 5

Lead required to shield .511 MeV gamma’s is more than 13 times that
of 140 KeV
What are the half layer value comparisons?

Hint 5

Tc-99m 0.3 mm (< 1/64”)
F – 18 4.1 mm (5/32”)

Front 6

What is the most commonly used PET RP?

Back 6

FDG, which is an analog of glucose
what is the dosage and what is the scan used for?

Hint 6

between 8-20 mCi,avg is 10-15
used to locate tumors and metastasis

Front 7

What interferes with the uptake of FDG and what needs to be tested to prevent this interference?

Back 7

High serum glucose, needs to be tested, pt should fast and be <200

Why is the pt scanned from mandible to mid-thigh?

Hint 7

brain is too hot since is runs purely on glucose

Front 8

When doing a muscle scan what should the patient avoid in order to get a good scan?

Back 8

Vigorous exercise 48 hrs prior to exam, even foot tapping and gum chewing can give a false positive!