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7 Cards in this Set

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what is the quantity and location of parathyroid glands?
Usually 4 located on the posterior aspect of thyroid gland, 2 superior and 2 inferior, although it is possible to have aberrant glands located elsewhere
What do the parathyroid glands secrete?
PTH - parathyroid hormone
what does this do?
Regulates the level and distribution of calcium and phosphorous
What is hyperparathyroidism?
over secretion of PTH
what are its causes?
parathyroid adenoma (80-85%)
parathyroid hyperplasia (10-15%)
multiple adenomas (2-3%)
carcinoma (<1%)
What could be a secondary cause for hyperparathyroidism?
chronic renal failure in which calcium metabolism is altered leading to enlargement of parathyroid glands
what could be a tertiary cause?
overstimulation chronically leading to autonomouse secretions
What is the Tl-Tc subtraction imaging for parathyroid?
inject 2-3 mCi Tl-201, image after 5 min, then inject 5-10 mCi Tc pertechnetate, wait 5-10 min. Tl-201 concentrates more on parathyroid and is taken up by both thyroid and parathyroid while Tc is only thyroid, subtraction study shows parathyroid
What is the Tc-I-123 subtraction study for parathyroid?
just like Tl-Tc subtraction but with these two isotopes: image @ 4 hrs for 300 microcuries of I-123 and 20 min for 20 mCi of Tc Sestamibi
What is the protocol for a Tc-Tc study for parathyroid?
Inject 25mCi of Sestamibi, acquire 3 consecutive 7 minute images, after 1 hr inject 10-15 mCi of pertechnetate and do delayed image comparing the 2