Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
25 Cards in this Set
- Front
- Back
|
I-131 NaI: 364 keV, T1/2 = 8 days
Nasopharynx Oropharynx Salivary Glands Stomach Bowel Bladder Breasts Critical Organ = Thyroid Indications = Thyroid cancer therapy, Thyroid Ca imaging f/u |
|
|
I-123 NaI: 159 keV, T1/2 = 13.2 hrs, dose = 200 - 400 uCi
Thyroid Salivary Glands Oropharynx Nasopharynx Breasts Stomach GI tract Bladder Critical Organ = Thyroid Indications = Benign thyroid disease evaluation |
|
|
Tc99mO4- pertechnetate: 140 keV, T1/2 = 6 hours
Thyroid Stomach Salivary glands Choroid plexus Critical organ = stomach/colon Indications = Thyroid, Meckel's Flow agen |
|
|
Ga-67 citrate: 93, 184, 300, 393 keV, T1/2 = 78 hours, dose 5 - 10 mCi
Fe analogue: transferrin and lactoferrin required for normal distribution Liver > spleen Bone Bone marrow Lacrimal glands Large bowel after 24 hours Renal excretion in first 24 hours Breasts Critical organ = colon and bone marrow Indications = Lymphoma, HCC, Infection |
|
|
Bone Scan Tc99m MDP: 140 keV, T1/2 = 6 hours, dose 25 mCI
Bone (depends on osteoblastic activity) Kidneys Bladder Critical organ = bladder Indications = Mets, evaluation of primary neoplasm, Tumor staging, infection, trauma, metabolic bone disease |
|
|
Tl-201 Cl: 69-83 keV, 167 keV, T1/2= 73 hours (biologic 10 days), dose limited to 3 mCi
Uptake proportional to blood flow except brain and fat 1st pass extraction by heart Heart Liver Spleen Gut Kidney Muscle uptake Indication = cardiac perfusion and viability, tumor seeking agent |
|
|
Tc99m MIBI: 140 keV, T1/2 = 6 hours, dose 10-30 mCi
Heart Muscle Liver Hepatobiliary system Bowel Kidney Bladder Indications = Myocardial perfusion, parathyroid adenom, general tumor imaging agent |
|
|
I-123 MIBG: 159 keV, T1/2 = 13.2 hours, Dose = 8mCi
Salivary glands Heart Liver Gut Bladder +/- adrenals NO bone or bone marrow uptake Indications = neuroblastoma, pheochromocytoma |
|
|
I-131 MIBG: 364 keV, T1/2=8 days, Dose = 500 uCi
Salivary glands Heart Liver Gut Bladder less likely to see adrenals c/w I-123 MIBG Indications = neuroblastoma, pheochromocytoma |
|
|
In-111 WBC: 172, 247 keV, T1/2 = 2.8 days, Dose = 500 uCi
Spleen > Liver > Bone marrow Indications = Infection, Inflammation |
|
|
Tc99m HMPAO WBCs: 140 keV, T1/2 = 6 hours, Dose 5-20 mCi
Liver Spleen Blood pool Indications: Infection, Inflammation |
|
|
In111 Octreotide: 172, 247 keV, T1/2 = 2.8 days, Dose = 6 mCi
Somatostatin receptor analog Liver Spleen Kidneys GI tract Bladder NO Bone and marrow Indications = Neuroendocrine tumors, pituitary adenomas, meningiomas, breast cancer, inflammatory lesions |
|
|
In111 Zevalin: 172, 247 keV, T1/2 2.8 days, Dose = 5 mCi
Liver Spleen Marrow Blood pool Indications = Refractory or relapsed low grade follicular or transformed B Cell NHL, used to check for normal biodistribution prior to Y-90 Zevalin admin |
|
|
In-111 Prostascint: 172, 247 keV, T1/2 = 2.8 days, Dose = 5mCi
Liver Spleen Marrow Blood pool Antibody binds to PSMA on prostate cells Indications = evaluate metastatic disease in CAP |
|
|
Tc99m RBCs: 140 keV, T1/2 = 6 hours, Dose = 5 to 20 mCi
Blood pool Heart Liver Spleen Kidneys Great vessels Indications = GI bleeding scans, gated cardiac blood pool scans, hemangioma evaluation |
|
|
Tc99m Sulfur Colloid: 140 keV, T1/2 = 6 hours, Dose 5 to 20 mCi
Colloidal particles phagocytosed by reticuloendothelial system Liver 85% Spleen 10% Marrow 5% Indications = Liver/spleen scan, bone marrow scan, primary liver cell neoplasm evaluation (FNH) |
|
|
F-18 FDG: 511 keV (positron emitter), T1/2 = 110 minutes, Dose = 5 to 20 mCi
Glucose analogue Brain Heart GI tract Breasts GU tract Indications = Tumor disease, staging and response, cardiac viability , brain scans |
|
|
DDx: Heart Uptake
|
Normal:
MIBI Thallium MIBG FDG Abnormal: Bone scan (infarct or infiltrating CM like amyloid) Gallium or WBC scan: CM, pericarditis, endocarditis |
|
|
DDx: Bone Uptake
|
MDP (Bone): Bone and Kidneys
Gallium (Bone and Bone Marrow): Bone with Liver > spleen, gut, minimal renal uptake Sulfur Colloid (bone marrow): Liver > Spleen > Bone Marrow WBC scan (Bone marrow): Spleen > Liver > Marrow |
|
|
DDx: Bone Uptake with Liver and Spleen
|
Normal:
Gallium (Liver > spleen, gut) WBC scan (spleen > liver) Sulfur colloid (Liver > spleen except in ESLD) Abnormal: Focal liver uptake: metastatic disease Diffuse liver spleen uptake: RP problem or Al+3 contamination Splenic uptake: Splenic infarction in SCD or in hemoglobinopathy |
|
|
Focal Liver Uptake on Bone Scan
|
Metastatic lesions with necrosis and/or high mucinous content
typically HCC or metastatic colorectal cancer May also be seen with mets from Breast, Lung and Ovarian Ca In kids, focal abdominal uptake in neuroblastoma |
|
|
Diffuse liver uptake on bone scan
|
Hepatic anoxia
RP prep = Al breakthrough from generator RP prep = TcO2 colloid formation Previous LS scan Rare: metastatic calcifications, amyloid, thalessemia or increased serum Al levels |
|
|
DDx: Splenic uptake on bone scan
|
Splenic infarct
Hemoglobinopathies Leukemia Lymphoma Hemosiderosis Dystrophic Calcifications |
|
|
DDx: No bone with liver/spleen/kidneys
|
In-111 octreotide: Liver, Spleen, Kidneys
I-131 MIBG or I-123 MIBG: Liver, Heart, Gut, Kidneys, Bladder |
|
|
Dystrophic calcifications on bone scan:
|
Hypercalcemia
Hyperparathyroidism Renal osteodystrophy Hypervitaminosis D |
