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54 Cards in this Set

  • Front
  • Back
What causes shock?
inadequate perfusion; or imbalance between oxygen supply and demand
What is shunting?
moving oxygenated blood into selected areas while bypassing others
When is the initial stage of shock present?
when client's MAP is decreased by less than 10mmHg
What are the characteristics of Stage 1 or compensatory shock?
MAP decrease 10-15mmHg, RAAS increases; patient looks right but vitals are unstable
What labs might indicate shock?
signs of metabolic acidosis, decreased bicarbonate, increased potassium and lactic acid
What occurs during Stage 2?
MAP is decreased 20mmHg, O2 not sufficient, hypoxia, hyperkalemia, lactic acid accumulation, hypotensive
How is hypotension corrected?
fluid resuscitation and or vasopressors
What are the characteristics of Stage 3?
mega cell death, shock is irreversible due to prolonged damage
What are the cardiac manifestations of shock?
myocardial cells become hypoxic, HR increases, nonpalpable pulses, dysrhymthmias due to potassium
What are the respiratory manifestations of shock?
increased RR, CO2 increases causing respiratory acidosis, ARDS can occur
What are the GI manifestations of shock?
organs become ischemic, stress uclers, paralytic ileus
What are the liver manifestations of shock?
gluconeogenesis leading to hypoglycemia, fat metabolism impaired
What are the mental manifestations of shock?
changes in mental status and orientation, lethargic
What are the renal manifestations of shock?
blood is shunted to brain and heart, oliguria, renal failure
What are the types of shock?
hypovolemic, cardiogenic, obstructive, distributive, septic, neurogenic, anaphlactic
When does hypovolemic shock occur?
when too little circulating blood volume causes a decreased MAP
What are the clinical manifestations of hypovolemic shock?
increased HR, absent PP, decreased O2, skin pallor, decreased systolic BP
What is the Rx for hypovolemic shock?
oxygen, fluids, crystalloid fluids, LR, isotonic
What does LR contain?
sodium, chloride, calcium, potassium, and lactate dissolved in H20
What is isotonic fluid?
helps expand volume and the lactate helps buffer any acidosis
What are vasoconstricting drugs used to treat hypovolemic shock?
dopamine, NE
Which drug enhances myocardial perfusion?
sodium nitroprusside
What is cardiogenic shock?
the heart cannot maintain cardiac output
What is the most common cause of cardiogenic shock?
acute MI
What are the manifestations of cardiogenic shock?
visible distress, dyspnea, tachycardia, hypotension, JVD, murmurs
What is the Rx for cardiogenic shock?
fluids, vasopressors, dopamine (increases BP), morphine for pain,
What is obstructive shock?
flow of blood is obstructed; impedes perfusion and can cause cardiac arrest
What is distributive shock caused by?
decreased systemic vascular tone characterized by a decreased systemic vascular resistance; hypotension
What is the most common type of vasodilatory shock?
septic shock
What is septic shock associated with?
severe infection and the release of inflammatory mediators
What is often released during septic shock?
endotoxins
Which type of bacteria most often causes septic shock?
gram-negative
What is the criteria for septic shock?
temp >38C, HR >90bpm, RR>20,
WBC >12,000
What are cytokines?
promote endothelial leukocyte adhesion, cell damage proteases, prostaglandins and activation of clotting cascade
What is the result of too many cytokines in septic shock?
major cap permeability and vasodilation....fluid shifts
Why does the skin become flushed and warm in the early stages of septic shock?
because of the vasodilation
What are some of the late signs of septic shock?
tachycardia, rapid respirations, cool, pale skin, lethargic to comatose, oliguria, decreased CVP
What lab MUST be checked for septic shock?
lactate levels (if >4mmol/dl) indicates hypo-perfusion
Which increased lab value is associated with low rates of survival?
WBC > 50,000
What is the Rx for septic shock?
control the causative agent (right ABX), PA cath, oxygen, fluid resuscitation, dopamine, NE
What is recombinant human activated protein C?
an endogenous protein that not only promotes fibrinolysis and thrombosis and inflammation but also shows signs of modulating the coagulating and inflammatory mediators in severe sepsis
Why is tight glycemic control important for the Rx of septic shock?
shown to decrease mortality rates; blood sugar should be maintained from 80-110mg/dL
What is used only in severe sepsis and is indicated for the reduction of mortality in adults with high risk?
Xigris
What is neurogenic shock?
occurs when a condition increases parasympathetic stimulation or inhibits sympathetic stimulation of smooth muscle
How is neurogenic shock characterized?
loss of vascular tone and reflexes
What is the most severe systemic allergic reaction?
anaphylactic shock
What is distributed into the blood stream in anaphylactic shock?
histamine and other vasoactive amines
What is the treatment for anaphylaxis?
Epi for severe, Benadryl, O2, steroids, bronchodilators
This is the formation of fibrin clots and thrombotic occlusion of small and mid-sized vessels caused by endotoxins and inflammation?
Disseminated Intravascular Coagulation
How is DIC characterized?
widespread clotting and bleeding
What are the manifestations of DIC?
hemorrhage, oozing of bleeding, purpura, petechiae, bruising, GI bleeding, blood sputum
This indicates the presence of abnormally high levels of fibrin degredation products in the body.
D-dimer/FDPs
This inhibits further thrombogenesis?
heparin
This inhibits fibrinolysis through the inhibition of plasminogen activator substances
Aminocapric acid (Amicar)