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15 Cards in this Set
- Front
- Back
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What is the primary cause of ischemic and thrombi disease processes in humans?
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Atherosclerotic plaque formation
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What can plaque cause? (x3)
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coronary artery disease, peripheral artery disease, and some types of CVAs
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How many types of plaque are there? What are they called?
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Two
stable and unstable |
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What happens to unstable plaque? (x2)
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Attracts platelets and ruptures
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What happens when unstable plaque ruptures?
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Occludes an artery
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define infarction (2 parts)
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when the artery occludes and tissues distal to the occlusion die
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What does STABLE PLAQUE result in? (2 parts)
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angina or
intermittent claudication type syndromes |
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5 steps to PLAQUE FORMATION
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1. STREAKS - fatty streaks form on the intima of arteries
2. a. LESIONS form with a fat deposited in center 2. b. FIBROUS & SMOOTH MUSCLE cover the fat 3. MONOCYTES are attracted and deposited (indicates INFLAMMATION) 4. HEMORRHAGE &/or ULCERATION as lesions become more advanced |
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What are the three factors associated with the RUPTURE of the PLAQUE?
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1. The size of the LIPID CORE and the smoothness of the FIBROUS CAP
2. The presence of INFLAMMATION 3. The lack of SMOOTH MUSCLE cells |
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What are the four nonmodifiable risk factors for MI?
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age, family history, race, gender
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Re: AGE, who gets more MIs?
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Older people,
Post menopausal women |
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Re: RACE, who gets more MIs? (2 types)
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Black,
Native American |
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Re: GENDER, who gets more MIs?
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men
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What are three examples of MODIFIABLE RISK FACTORS?
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1. Cigarette smoking
2. Dyslipidemia (Hyperlipidemia) 3. Physical inactivity and obesity |
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What are three examples of SEMI-MODIFIABLE RISK FACTORS?
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1. Hypertension
2. Diabetes Mellitus 3. Genetic Dyslipidemia |
