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8 Cards in this Set

  • Front
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Risk assessment ____________ provide information on morbidity or mortality.
Risk assessment DOES NOT provide information on morbidity or mortality.

Instead it can make suggestions to reduce risk.
RELATIVE RISK (RR)
How common a disease is developed among people who are exposed, to a possible risk factor of those who are not exposed.

EXAMPLE: RR in Cigarette smoking
Nonsmokers: 11 out of 100,000 will develop lung cancer
Smokers: 131 out of 100,000 will develop lung cancer
131/11 = 11.9 - Smokers are 11.9x more likely to develop lung cancer compared to non-smokers
RELATIVE RISK (RR)
- Referent Group
"unexposed group"
RELATIVE RISK (R)
- Interpretation
RR close to 1 = link to exposure and disease is unlikely to exist

RR greater than 1 = likelihood of the exposed developing the disease is higher and of concern

RR much lower than 1 = risk decreases with exposure

GUIDE: Above 3 start of concern; Below 0.6 start of improvement
ODDS RATIO (OR)
# with disease who have the risk factor
DIVIDED BY
# without disease that have the risk factor

EXAMPLE:
95 out of 100 people with lung cancer smoke cigarettes
25 out of 100 people w/o lung cancer smoke cigarettes
95/25 = 3.8 - OR for smoking & lung cancer
The main problem with using RISK RATIO and ODD RATIO is ________________________________________________.
The main problem with using RISK RATIO and ODD RATIO is not all risk factors can be/are measured.
HAZARD RATIO / COX PROPORTIONAL HAZARD RATIO
Measure how often a particular event happens in one group compared to how often it happens in another group, over time.

Hazard ratio of 1 = no difference in survival between the two groups

Hazard ratio of greater than one or less than one means that survival was better in one of the groups
Major Points / Differences of Hazard Ratios
-Compares what happens in groups
-Hazards are assumed to be constant over time
-Endpoint is "resolution of disease" (improvement, cure or death)