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13 Cards in this Set

  • Front
  • Back

Aspirin

Aspirin

Ketorolac

Toradol

Celecoxib

Celebrex

Valdecoxib

Bextra

Ibuprofen

Ibuprofen

Indomethacin

Indomethacin

Naproxen

Naproxen

Expected action

COX 2 inhibition leads to decreased inflammation




COX 1 leads to decreased platelet aggregation

Therapeutic Uses

Inflammation suppression


Analgesia




Dysmenorrhea/suppression of platelet aggregation

Adverse Effects

GI discomfort


Aspirin induced ulceration and bleeding


Renal dysfunction


Reye syndrome


Salicylism (tinnitus, resp alkalosis, dizziness)

Contraindications/Precautions

Peptic ulcers


Bleeding disorder


Hypersensitivity


Kids with viral infection

Interactions

Warfarin, Ethonol: Increases bleeding


Glucocorticoids: Increase gastric bleeding



Education

Give with food or milk to reduce GI discomfort