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40 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Which NRTIs are dosed daily?
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D.A.T.E
abacavir didanosine tenofovir emtricitabine |
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Which NRTIs are dosed every 8 hours?
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zalcitabine
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Which NRTI suppresses bone marrow?
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zidovudine
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What NRTI will cause patients GI intolerance?
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zidovudine
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Which NRTI causes anemia?
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zidovudine
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Which NRTIs have minimal toxicities?
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lamvudine
emtricitabine |
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Which NRTI causes (but rarely) hyperpigmentation of palms or hands and soles of feet?
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emtricitabine
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Which NRTI causes potentially fatal hpersensitivity reactions characterized by rash and fever?
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abacavir
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Which NRTI's cause pancreatitis and peripheral neuropathy?
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the "Ds"
didanosine stavudine zalcitabine |
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Which NRTI causes renal insufficiency?
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tenofovir
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Which NRTIs have no clinically significant drug interactions?
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lamivudine
emtricitabine |
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Which NRTI when mixed with alcohol increases its own levels by 41%?
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abacavir
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Which NRTIs interact with methadone?
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zidovudine
didanosine |
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Which NRTI interacts with bactrim?
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zidovuine
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What type of monitoring do all NRTIs require?
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Lactic acidosis (ABG <7.35, tissue hypoxiacyanosis , cool extremities, tachycardia, hypotension, dry mucous membranes, dyspnea, confusion, lethargy, stupor, or coma. Hyperventilation is common as a compensatory mechanism causing respiratory alkalosis.) and
hepatic steatosis (enlarged liver & splean, pain & tenderness, fatigue, elevated cholesterol, elevated ALT & AST, ) |
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What is the name of the combination product that includes zidovudine & lamivudine?
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Combivir
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What is zidovudine, lamivudine and abacavir?
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Trizivir
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What is abacavir and lamivudine?
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epzicom
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What is tenofovir and emtricitabine?
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Truvada
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Though most NRTIs need renal adjustment for those with renal impairment, which NRTI(s) do not?
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abacavir
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Which NRTI(s) are dosed based on weight?
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didanosine
stavudine lamivudine |
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Which NRTIs are so chemical similar that they should not be combined?
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emtricitabine an
lamivudine |
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Which NRTI(s) need to be taken 30 minutes before food or 2 hours after food?
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didanosine
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Whish NRTIs antagonize each other and why?
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zidovudine and
stavudine because they both require thymidine for activation |
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Which NRTIs when combined and used durring pregnancy cause an increase in lactic acidosis and liver damage and should not be used together?
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didanosine and
stavudine |
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Which NRTI does tenofovir increase?
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didanosine, dose adjust
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Which NRTI does tenofovir decrease?
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atazanavir, dose adjust
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How should NRTIs be stored?
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no special storage requirements needed.
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Which NRTI(s) can cause pancreatitis and peripherial neuropathy which are additive when used together?
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The Ds
ddI- didanosine ddC- zalcitabine d4T- stavudine |
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Which NRTI(s) are more closely associate with lactic acidosis?
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The Ds
ddI- didanosine ddC- zalcitabine d4T- stavudine |
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Which NRTI(s) has the highest incidence of peripheral neuropathy?
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Zalcitabine
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Which drugs are contraindicated in combination with zalcitabine?
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B/C ddC has the highest incidence of peripheral neuropathy
3TC- lamivudine ddI- didanosine d4T- stavudine |
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zidovudine
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Retrovir
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AZT or
ZDV |
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lamivudine
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Epivir
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3TC
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abacavir
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Ziagen
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ABC
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didanosine
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Videx
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ddI
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stavudine
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Zerit
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d4T
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zalcitabine
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Hivid
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ddC
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tenofovir
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Viread
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TDF
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emtricitabine
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Emtriva
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FTC
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