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20 Cards in this Set

  • Front
  • Back
Drugs: Chemoreceptor trigger zone -> vomiting center
Histamine antagonists
Muscarinic antagonists
Dopamine antagonists
Cannabinoids
Drugs: Stomach / small intestine -> chemoreceptor trigger zone
Sphincter modulators
5HT3 antagonists
Drugs: Stomach / small intestine -> vomiting center
5HT3 antagonists
Risk factors / increased level of concern
Blood in vomit / "coffee ground" appearance
Stiff neck
Severe headache
Lethargy
Confusion
Severe abdominal pain
Fever > 101
Diarrhea also present
Rapid deep breathing
Rapid pulse
Antihistamines
Meclizine
Cyclizine
Diphenhydramine
Doxylamine
Dimenhydrinate
Antihistamines: Consequences of use
Drowsiness
Dry mouth & eyes
Urinary retention
Constipation
Bonine
Meclizine
Marezine
Cyclizine
Dramamine
Dimenhydrinate
Meclizine (less drowsy)
Accupressure point
P6
Neiguan
Morning sickness treatments
Antihistamines
Vitamin B6 (pyridoxine)
Ginger
Phosphorated carbohydrates
Preggie-Pops
Accupressure
Vitamin B6: Dose
10 to 25 mg tid
Ginger: NMCD rating
Possibly effective
Ginger: MOA
Galanolactone acts primarily on 5HT receptor in ileum
Some central action
Ginger: Consequences of use
Usually well-tolerated
Doses 5 gm & higher give increased side effects (mostly GI, heartburn, etc.)
Ginger: Dose
250 mg qid
Phosphorated carboyhydrate solutions: MOA
Decrease smooth muscle contraction & delay gastric emptying
Dose-dependent effect
Phosphorated carbohydrate solutions: Consequences of use
Upset stomach
Large doses: Diarrhea, abdominal pain
Phosphorated carbohydrate solutions: At-risk populations
Diabetics
Fructose-intolerant persons
Hangover: Best therapies
Hydration
Time