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26 Cards in this Set
- Front
- Back
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Normal MCV with anemia
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acute bleeding anemia
can be aplastic anemia |
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What cells are seen in G6PD
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Bite cells
Heinz bodies |
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What blood condition is important to consider in a person with liver failure (cirrhosis) and/or pancreatic failure (diabetes, spec "bronze diabetes")
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Hemochromatosis
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how does Henoch-Schonein Purpura present
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Occurs in Child
Pupuric rash on lower extremities Abdominal pain or renal involvement (hematurea microscopic) Arthritis |
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What is ITP
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Antibodies form against platelets
add to this slide |
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How does TTP present
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Microangiopathic hemolytic anemia (schistocytes, helmet cells on smear)
Elevated LDH Mental status changes or fluctuating focal neurologic deficits |
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What is Hemolytic Uremic Syndrome
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Usually in infants, children, or pregnant or postpartum women
Hemolytic anemia with Kidney failure Usually d/t infection, can be d/t drug rxn |
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Describe Von Willebrand's dz
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Small problems in clotting - heavy menses, epitaxis, Easy bruising, GI bleeding are common
Dec serum levels of factor VIII:C |
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Describe DIC
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Complication of obstetrics
Infection Malignancy Clinically may mimic liver failure with elevated PT/INR and decreased platelets. Subacute. Thromboembolic events including DVT, heart valve thrombosis, stroke, extremity infarction, etc. Acute. Serious bleeding complications with depletion of clotting factors. |
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ALL
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Mainly in kids
bone pn lymphadnopathy splenomegaly pallor fever |
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What is lactoferin
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It is triggered by a bacterial infection. It is used to sequester Fe to protect it your body of loosing the Fe to the bacteria. This will make the serum iron look really low.
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What is the upside of heme iron and what is the downside of this
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Non-heme iron is not regulated in uptake so it is easily absorbed. The problem is in a person with iron overload, they will keep absorbing Fe.
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What substrates are key in building porpharyns and therefore key in making heme
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B6
Glycine Succinate |
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What is a right shift in the blood work
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It indicates a methylation defect - it is segmented neutraphils.
B12 or folic acid deficiency |
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What is the most common hemolytic anemia
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G6PD
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How can Hodgkin's dz present
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episodic fever and sweats, SVC obstruction, generalized puritis
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Mediastinal, splenic medsenteric or para-aortic abdominal node dz is seen in Hodgikins or non-hodgkins
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Non-Hodgkin's dz
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High zinc consumption can lead to what deficiency and result in what condition
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copper deficiency causing a micro-cytic hypochromic anemia
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What effect does iron Vit C and folic acid ...
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add
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Which of the leukemias has the worse prognosis
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CML
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What chromosome is associated with CML
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Philadelphia chromosome
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What is suggestive of Hodgkin's lymphoma
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Reed Sternburge
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What plasma cells are associated with Multiple meyloma
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Bence Jones proteins
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Is gastric carcinoma associated with folic acid deficiency
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no
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What is blind loop syndrome
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over growth of bacteria in the gut
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What types of autoantibodies are associated with perniciuos anemia
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autoantibodies to gastric parietal cells, intrinsic factor and antithyroid antibodies
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