Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
40 Cards in this Set
- Front
- Back
what imaging study is often used in the dx of dementia?
|
SPECT
|
|
tertiary neurosyphilis causes what neurological sx?
|
tabes dorsalis:destruction of dorsal roots, impaired sensation and ataxia, absent DTRs
|
|
what percentage of people die of encephalitis?
|
35%, sx of worsening HAs with systemic signs and sx
|
|
Most common primary brain tumor in adults?
|
glioblastoma multiforme(grade 4=astrocytoma)
|
|
Sx of brain tumor?
|
personality changes, HAs, drowsiness, lethargy, psychosis, vomiting, papilledema
|
|
4 peripheral nerve tumors?
|
neurofibromatosis=autosomal dominant with mutations
Shwannoma/acoustic neuroma= CN8, benign <1% malignant |
|
sx of optic neuritis, glove and stocking parasthesias, higher risk in the northern latitudes, autoimmune demylenation in the CNS?
|
Multiple Sclerosis
|
|
2/3 preceded by flu, ascending paralysis, DTR's absent, sensation intact, acute onset (polyradiculopathy), PNS
|
Guillian-Barre syndrome
|
|
alcoholic with short term memory loss and confabulations
|
wernicke-korsakoff syndrome (B1 deficiency)
|
|
dementia, dermatitis, diarrhea leading to death; what nutritional deficiency?
|
niacin deficiency
|
|
macrocytic anemia, degeneration of the spinal cord:spasticity, weakness, loss of proprioception,dementia; not cured with folate deficiency
|
B12 deficiency
|
|
New HAs in pt over 50 should be evaluated b/c of what dx?
|
ischemic cerebrovascular dz; 25% of pt with carotid or middle cerebral vascular dz or 50% of pt with vertebrobasilar insufficiency
|
|
Hydrocephalus is an increase in what fluid? and what ventricles swell?
|
CSF, lateral 3rd and 4th
|
|
atrophy of hypothenar eminence and interosseous mm. of hand; also parasthesias of 1/2 of ring finger and 5th finger on palm surface
|
Ulnar palsy
|
|
problems with the brachial plexus; radiculopathy,numbness and tingling of the arm d/t compression by cervical rib, lymphoma, vascular malformation
|
thoracic outlet syndrome
|
|
viral infx of 7th nerve leading to unilateral facial paralysis, no sensory loss,
|
bells palsy
|
|
dry mouth, diplopia, ptosis, loss of accomadation and pupillary reflex--GI sx precede, descending paralysis
|
Botulism
|
|
severe, unilateral HA with nasal congestion, less than 4 hrs long q weekly
|
cluster HA; more common in men no fam HX
|
|
nausea and vomiting; photophobia with HA; hibernates; females more common
|
migraine; fam hx
|
|
dull HA; steady; daily and worse with stress
|
tension HA
|
|
HA after 50 yrs of age
|
temporal arteritis; vertebral/carotid insufficiency
|
|
difference b/t classic and common migraine
|
prodrome with classic
|
|
tx for migraines? and works how?
|
triptans; sumatriptan; causes vasoconstriction by binding (5HT1)
Ergonavine-vasoconstriction, can cause hypertension/seizures |
|
HA can occur 6-8x/day; alcohol can trigger;unilateral and periorbital; more in men; no n/v
|
cluster HA
|
|
shooting pain from 5th trigeminal nerve;can be triggered by touch, drafts, brushing teeth
|
trigeminal neuralgia
|
|
malaise; proximal mm. pain; jaw claudication; tender scalp arteries
|
giant cell arteritis; 50% can progress to blindless; ESR >100
|
|
MRI shows plaques and periventricular white matter; demyelination of brain and spinal cord
|
MS
|
|
dx of muscular dystrophy?
|
mm. biopsy is definative; CK greater than 2000 in duchenes
|
|
progressive non-inflammatory mm. fiber degeneration
|
muscular dystrophy
|
|
stiffness, inability to release grasp, thick speech, mm. atrophy in face and neck, onset 20, slowly progressive (cataract, testicular atrophy, intelectual changes)
|
myotonic dystrophy; autosomal dominant
|
|
motor manifestations of non-progressive brain damage during prenatal/postpartum period;spasticity (70%); quadrapalegic (low IQ, dysarthria, poor feeding); hemiplegic or diplegic (bilat spasticity, clumsy norm IQ)
|
cerebral palsy
|
|
progressive degeneration of corticospinal tract and/or ant. horn cells; dz of later or mid life; decrease DTRs; fasiculations of mm. weakness of arms/legs;bulbar involvement: dysarthria, dysphagia, tongue atrophy
|
ALS; 50% die in 3 yrs, 90% in 6 yrs
|
|
autoimmune d.o. affecting acetylcholine receptors; women in 20s and men in 40-50s; weakness on exertion; weakness of ocular, proximal, pharyngeal and respiratory mm.
|
myasthenia gravis
|
|
test for myasthenia gravis?
|
tensilon test; better when an acetylcholinesterase inhibitor
|
|
most common movement d.o.; tremor not present at rest
|
benign essential tremor
|
|
slow movement; muscular rigidity; resting tremor; postural instability; shuffling instability; pill rolling; masked facies?
|
Parkinson's dz
|
|
movement d.o. manifesting in the 3rd or 4th decade; fidgetign or restlessness progressing to writhing movements; dementia follows
|
Huntington's dz; child has 50% chance of inheriting
|
|
most common cause of dementia; clinical exam shows greater than 2 deficits; progressive worsening
|
alzheimer's dz
|
|
alzheimers dz dx
|
SPECT
|
|
depression; simple delusions; behavioral change; wandering; screaming
|
alzheimer's dz
|