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8 Cards in this Set
- Front
- Back
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What type of T cells seek out specific pathogens and destroy them in "hand-to-hand" combat?
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Cytotoxic T cells
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How do Cytotoxic T cells destroy pathogens?
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in hand-to-hand combat
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What do the storage vacules in cytotoxic T cells contain?
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Perforins and granzymes
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What happens after a cytotoxic T cell binds to a virus-infected cell or tumor cell?
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It releases perforin molecules, which punch holes into the plasma membrane, forming a pore.
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After Cytotoxic T cells punch a hole through the plasma membrane of T cells, what do they deliver into the pore? What punches the hole?
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granzyme that cause the cell to undergo apoptosis and die. Perforins
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What are perforins and granzymes?
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perforins form hole in target cell
granzymes enter through the hole and cause it to undergo apoptosis |
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What type of cells are responsible for Cell mediated immunity?
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cytotoxic T cells
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Where are cytotoxic T cells derived from?
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A subgropu of T cells produced during Clonal expansion display an antigen within the groove of an MHC I protein, these T cells activate and become cytotoxic T cells
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