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49 Cards in this Set
- Front
- Back
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Innate
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born with; have automatically
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Acquired
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have to develop; not born with
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Immunology
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encompasses the study of all features of the body's 2nd and 3rd lines of defenses
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First Line of Defense
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any barrier that blocks invasion at the portal of entry
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Second Line of Defense
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more internalized system of prectective cells and fluids
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Second Line of Defense
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inflammation and phagocytosis
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Physical Barriers
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skin, eyelashes, tears, blinking, ciliary in lungs, urination saliva
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Chemical Barriers
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bile acids, pH of stomach, pH of vagina
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Chemical Barriers
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tears break down peptidoglycan layer
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Genetic Barriers
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sickle cell anemia can't get melaria
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Immunology
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the study of the ability of the white blood cells to resist infection
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Immunology
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the ability of the wbcs to recognize non-self (foreign cells)
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RES, Blood, Lymphatic System, Organs
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help wbcs to get where they need to be
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RES
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run between every cell and every organ in the body
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RES
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where extracellular system flows
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RES
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where white cells can travel
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Lymphatic System
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bring excess fluid back to the heart
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Lymphatic System
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CARRY wbs around the body
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Carriers
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have bacteria but not exhibiting symptoms
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WBSs
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always on watch for foreign materials
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Neutrophils
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leukocyte, lobed nuclei, lavender granules; released from the bone marrow
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Basophils
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pale stained, leukocyte, 0.5% of total WBC, mast cells
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Eosinophils
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numerous in the bone marrow and the spleen; prominent in inflammation and allergic reactions
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Monocytes
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largest of all wbc; discharged from bone marrow, small version of macrophage, mature mast cell
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Lymphocytes
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3rd line of defense
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Macrophage
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largest wbc; clean up crew
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Dendritic Cells
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move from the blood to RES and lymphatic tissues where they trap pathogens; migrate in lymph nodes and the spleen
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PAMP
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microorganism's surface patters
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WBCs
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neutrophils, dendritic cells, macrophages
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Chemical Mediators
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released when wbcs bind to microorganisms
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Chemical Mediators
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cause the body to go into action
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4 processes in 2nd line of Defense
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inflammation, injury, vascular reations, then edema and pus formation
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Inflammation
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a reaction to injury from a bacterial infection
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Phagocytosis
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partner to inflammation from a bacterial infection
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Interferons
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immune stimulants; VIRAL INFECTION
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Interferons
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stop other cells from producing more viruses
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Interferons
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can be given to patients to suppress tumor cells
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Complement
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backup system; punch holes in the microorganism's membrane, so the cytoplasm leaks out
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Thymus
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without - babies are severly immunodeficient and fail to thrive
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Primary Organs
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thymus and bone marrow
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Primary organs
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the sites of origin and maturation of lymphocytes
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2ndary Organs
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lymph nodes and spleen, malt, salt, galt; based locations where encounters with microbes and immune responses take place
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PAMP
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neutrophils, eosinophils, monocytes, macrophages, and dendritic cells have _ receptors
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MHCI Receptors
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all but T-helper cells have _ receptors
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MHCII Receptors
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macrophages, dendritic, and Bcells have _ receptors
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Tcell Receptors
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T-cytotoxic and T-helper cells have _ receptors
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CD4 receptors
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T-helper cell only one to have _ receptors
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Bcell receptor
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B-cell only one to have _ receptor
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CD8 receptor
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T-cytotoxic cell only to have _ receptor
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