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7 Cards in this Set
- Front
- Back
What are Nonprotein Nitrogens? What are the three major nitrogens biproducts? |
The breakdown products of protein and amino acids Blood Urea Nitrogen (BUN) Creatinine -Prod of Creatine Uric Acid - purine metabolism |
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When dealing with Blood Urea Nitrogen what are the Method, Specimen acq., and range? What are the two types of BUN? |
Urease reaction -Hydrolysis of urea by urease Plasma, Serum, Urine, Avoid Fluoride and Citrated tubes. RR: 6-20mg/dl >80 Crit Azotemia/Uremia |
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When dealing with Creatinine what is the specimen acq. and what is the main time it is seen? RR? |
Plasma, Serum, Urine, Avoid hemolysis and Icteric samples. Seen in Renal Dysfx and glomerular filtration RR 0.6-1.5mg/dl >4 Crit |
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What is GFR? What does it aid in? |
Glomerular Filtration Rate - Volume of plasma/time Creatinine Clearance and is assessed with renal dysfx |
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RR? |
CrCl=(Ucr*Vml/Pcr*Tmin)*(1.73/BSA) Urine Creatinine in mg/dl Tot Volume in ml Plasma Creatinine in mg/dl Tmin Time of collection in minutes BSA Body Surface Area M: 97-137ml/min F: 88-128ml/min |
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How is Uric Acid produced? What is the method and specimen collection? RR? |
Breakdown product of purine metabolism Enzymatic-choice? Heparinized plasma, serum, or urine. Avoid lipemia RR 0.5-7.2mg/dl 2.6-6.0mg/dl |
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What are some disease involving uric acid? |
Increased: Gout 30-50years old Renal Disease Decreased: Liver disease fanconi's syndrome & tubular reabsorption defects |