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75 Cards in this Set

  • Front
  • Back
How can you tell if pigmented lesion is a melanoma?
ABCD rule:
Asymmetry, Border irregularity, Color variation, Diameter >.6cm, Dark black color.
Also ulceration, nodularity, regional lymphadenopathy
When should skin lesions be excised?
Any characteristics of ABCD or has changed recently.
When a lesion is on the face, what kind of excision do you perform?
full thickness Incisional biopsy
Which type of skin lesions can be dangerous?
Basal cell carcinoma: maybe locally invasive. Reexcise if margins positive
Squamous cell carcinoma: more dangerous than BCC because its' locally aggressive and mets to local LNs. >4mm in thickness? 1cm margin. Topical 5FU or radiation is common.
What type of skin lesion is most dangerous?
Melanoma. If it's in situ, .5-1 cm margin needed.
What type of skin lesion is benign?
Dysplastic nevus. Transition between benign and melanoma. Excise and routine surveillance.
What factor determines staging of melanoma? What else is important?
thickness, histology, ulcerations becauae they have 1/3 reduction in survival
What locations on the body of skin lesions do worse?
Face or trunk worse prog than extremities. Women do better than men.
What to do for Clark Levels I and II?
Depth up to .75mm: reexcise with 1cm margin down to fascial plane.
Post excision for melanomas?
CXR, CBC, LFTs, warrant f/u only if abnormal
What to do for Clark level IV?
1.5-2.5mm, Reexcise with 2cm margin, lymphadenectomy only if nodes palpable
What to do for Clark level V?
>4mm: reexcision with 2-3cm margin, excision of palpable nodes, CTabd, MRI of brain, start tx w/ Interferon
What do palpable nodes mean?
Possible mets.
What's metastatic workup?
CXR, LFTs, CBC, CTabd, MRI brain, Interferons
With mets what are the chances of recurrence of melanoma?
75%
What specialized tx for stage IV?
Immunotx: Polyvalent vaccine vs tumor cells
What to do with melanoma and mets on CXR?
percutaneous lung biopsy, systemic tx with (chemo) Dacarbazine and immunotx. Resection of solitary lesions. Radiation if bone pain.
What's the benefit of immunotx?
In people with bone mets, complete resection with vaccine increases 5 year survival by 35%
What is irregular discoloaration on face?Tx?
lentigo maligna melanoma. It's superficial and spreading, favorable prog cause it's not thick. Excise with narrow margin.
What's the precursor to lentigo melagna melanoma? Tx?
Hutchinson's freckle. Observe for changes.
What are melanomas on the foot called? Who does it happen to? Tx?
acral-lentiginous lesion. happens to darker skinned people. Poorer prog. Excise according to thickness
What's a tumor under the nail called?
Subungual melanoma. After biopsy with portion of the nail, reexcision is amputation at the DIP.
Survival rate of subungual melanoma?
60%
Mortality of anal melanomas?
almost 100% at 5 years
Tx of anal melanomas?
Thin lesions can be excised, Thick lesions need abdominoperineal resection of anorectum. Regional LN resection for positive inguinal nodes.
Where does melanoma usually met to?
Small bowel. Explore, resent for palliation for obstruction.
What are sarcomas?
Rare neoplasms of connective tissue
What is assoc with sacromas?
Hx of therapeutic radiation or axillary lymphadenopathy (lymphangiosarcoma) 1-2 decades earlier
What can mimic sarcoma?
trauma and subsequent hematoma
How do sarcomas present?
firm, painless masses
How do you biopsy sarcomas?
<3cm: excisional biopsy
>3cm: incisional biopsy. larger defects make primary closure complex and potentially contaminates additional compartments with tumor
What determines low grade and high grade sarcomas?
# of mitotic figures and degree of necrosis
Rate of mets on presentation?
22%
Most common site of sarcomas mets?
liver, lung, bone, brain
What should you always do before resection of sarcoma?
met workup
How should you treat sarcoma?
Total compartmental resection, including muscle, origin and insertion, and investing fascia
What's the recurrence rate for sarcomas when it's a less than total compartmental resection?
15-50%
What do you do with a large high grade sarcoma?
Radical amputation or compartmental resection with neoadjuvant chemoradiation, and postop radiation
What type of sarcomas have been shown to be the only types to respond to chemo?
childhood retroperitoneal pelvic rhabdomyosarcomas
What type of imaging can detect mets?
CT/PET
When it is warranted to resect a met?
When it's same as the primary tumor, resectable, solitary. Do a thoracic wedge resection(s) for lung mets, it improves survival. Liver mets too.
Differential for tender lymph nodes in groin?
Lymphadenitis, malignancy, STDs, chancroid
Diff for tender testicle?
torsion, vircal orchitis, epididymitis
What's suspected diag when impulse travels down inguinal canal when cough?
indirect hernia
What's diag when firm tender mass below inguinal ligament?
Femoral hernia
What's diag when firm tender mass with nausea, vomiting, abd distension?
loop of intestine incarcerated or strangulated
What vessels determine direct or indirect?
Inferior epigastrics
What are signs of a strangulated hernia?
fever, leukocytosis, acidosis with hernia
Incidence of strangulation for patient with a known hernia?
1-3% per year
What type of hernias is strangulation most common for?
Femoral
Most common type of hernia?
Indirect. Then direct, then femoral
Conditions associated with hernia?
obesity, COPD, ascites, BPH, colorectal obstruction, constipation, anything that increases abdominal pressure
What should you do with a hernia?
Repair it cause it can get encarcerated and strangulated
What is Bassini repair?
weakness in transversalis fascia fixed by suturing Transversalis fascia, TA fascia and internal oblique fascia to inguinal ligament
Weakness of Bassini repair?
tension on tissues, likely to fail with poor tissues
McVay's repair?
Same as Bassini but structures are sutured to Cooper's ligament at periosteum of the pubic ramus. Then you make an incision in the anterior rectus sheath to relieve tension. Good for femoral hernias and attenuated inguinal ligaments
Shouldice repair?
Similar to Bassini except suture placed in multiple layers to redistribute tension
Dangers of Shouldice repair?
lose scrotal sensation b/c routine division of genital branch of genitofemoral nerve. but decreased recurrence rates
Lichtenstein repair?
uses prosthetic mesh to cover superior structures to inguinal ligament. no tension.
Nerves to watch out for in hernia repair?
Genital branch of genitofemoral, ilioinguinal, iliohypogastric, lateral femoral cutaneous.
Recurrence rate of hernia after repair?
1-10%
Complications of hernia repair?
Would infection, graft infection, testicular atrophy, edema, sensory defects, hematoma
F/u after hernia repair?
No lifting for 6 weeks, office visit 1 week and 6 weeks post surg to monitor healing, return if healing poor or hernia recurs
What is difference b/w pediatric and adult inguinal hernias?
Pediatric represent persistent processus vaginalis and have no defect in the floor or the inguinal canal. So, they're indirect hernias. High incidence of b/l.
How do you repair pediatric inguinal hernia?
high ligation and excision of the processus vaginalis, maybe need to plicate floor of canal (transversalis fascia) when internal inguinal ring is enlarged, reconstruction of the floor of the canal if large hernia
When do you want to surgically repair pediatric inguinal hernia?
manually or sugicaly reduce it first, then after 24-48 hours operate.
What are posterior and anterior structures of inguinal canal?
EO anterior, Transversalis and transversus abdominis posterior
What type of hernia more common in women?
Femoral
Procedure for femoral hernia?
McVay (Cooper's)
What other structures can get injured in hernia repair?
If it's a sliding hernia it involves bladder, cecum, sigmoid, can get injured
What's a Richter's hernia?
When only 1 sidewall of the bowel get herniated, can result in necrosis and perf w/o signs of obstruction
What is Littre's hernia?
Protrusion of Meckel's diverticulum (remnant of the yolk stalk) through hernia
Who get sliding hernias?
Males on the left side
How to repair sliding hernias?
LaRoque technique with entering peritoneum above internal ring to recognize pathological anatomy then reducing hernia. Don't try to dissect away from posterior wall of sac, just dissect cord away cause the bowel IS the posterior wall of the sac
Why should a ventral hernia be repaired?
Risk of incarceration and strangulation