Nitrogen Stuff

Front 1

Paris of alpha-ketoglutarate/glutamate transferases:

Back 1

aspartate/oxaloacetate

alanine/pyruvate

Front 2

aminotransferases

Back 2

transfer an amino group from amino acid (glutamate or alanine) to alpha-ketoglutarate.
Product: oxaloacetate or pyruvate + glutamate.

Front 3

what happens to glutamate after it is formed from aminotransferase:

what enzyme?

Back 3

Oxidative deamination.
2 steps:
1. take off H, form schiff base
2. hydrolyze schiff base - produce NH4+ and a-ketoglutarate
Enzyme: glutamate dehydrogenase

Front 4

What prosthetic group is required for aminotransferases:

Back 4

vitamin b6 cofactor:
pyridoxal phosphate in equilibrium wiht pyridoxamine phosphate

Front 5

ketogenic amino acids

Back 5

degradation produces acetyl CoA or acetoacetyl CoA and can only give rise to ketone bodies or fatty acids. (not glucose)

Front 6

glucogenic amino acids

Back 6

amino acids that degrade down to precursors of phosphoenolpyruvate to then make glucose.
Ex., pyruvate, a-ketoglutarate, succinyl coA, fumarate, oxaloacetate,

Front 7

Can mammals directly synthesize glucose from acetyl coA or acetoacetyl coA?

Back 7

no.