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6 Cards in this Set
- Front
- Back
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What is the role of the biofilm in the initiation of Periodontal Disease?
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It produces toxins which diffuse into the gingival tissues triggering immune responses
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What are the main stages tissue response to biofilm by Page and
Schroeder? |
Stage 1
- increase permeability of capilaries - chemotaxis of PMN cells Stage 2 - dilation of vessels > swelling / redness - further chemotaxis of immune cells - PMN and Lymphocytes dominate - few plasma cells are also found - degeneration of collagen Stage 3 - Plasma cells dominate - Chemotaxis PMN and Lymphocytes continues - mass production of powerful inflamation mediators (cytokines, interleukin) - junctional epithelium detaches and migrates apically - further and more degeneration of collagen |
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Which are the main antigenic bacterial products and how are they produced?
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- Enzymes (proteases), Leukotoxin
- Lipopolysaccharides of Gram -ve - Lipoteichoic acids of Gram +ve |
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Which are the main inflammation mediator molecules and how do they work?
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cytokines, interleukin
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How are inflammation mediators produced?
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PMN and lymphocytes product cytokines, and interleukin
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Which is the main mechanism of tissue destruction in periodontal
disease? |
Host immune responses towards bacterial products
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