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7 Cards in this Set

  • Front
  • Back
What is a biofilm and how is it structured?
Combinations of colonies of many bacterial species, polysaccharides and protein.
What are the main stages of development of dental plaque?
Pristine, polished enamel:
Pellicle
2:30hrs First wave: Gram+ cocci
Day 1 Colony expansion
Day 3 Second wave: Gram-
Day 12 Stric Gram-
What are the characteristics of each stage?
Pellicle: glycoprotein from saliva
2:30: First gram + attach to pellicle
Day 1: Expansion, secretion of extracellular polymers
Day 3: 2nd wave- gram-ves anaerobes due to deprevation of oxygen
Day 12: Very thick, multilayered. strictly anaerobes
Day 12+: inflammatory response
Why are bacteria in a biofilm a difficult therapautical target?
more resistant to antibiotics
Slower rate of growth of bacterial species in biofims
The exopolymer matrix can retard diffusion
What are the main differences in biofilm composition between
periodontal health and disease?
Health:

Cocci, streptococci Rods
Gram + Aerobic bacteria

Disease:

Gram –
Anaerobic bacteria
P. Gingivalis
T. Denticola
A. actinomycetemcomitans
What is the specific plaque theory and what the non-specific?
Non specific plaque theory: Composition of plaque differs from patient to patient and from site to site

Infection due to increase in mass of bacterial plaque

Specific plaque theory:
infection with specific species is responsible for major pathology
Which are the major bacterial complexes identified by Socransky and what is their involvement in periodontal disease?
T. forsythensis,
P. gingivalis,
T. denticola

pockets and bleeding on probing