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6 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Hexamethonium (MOA & PK)
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MOA - Reversibly inhibits ACh binding to nicotinic receptors
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PK - Quartenary amine; poorly/erratically absorbed after given orally
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Hexamethonium (CU & T)
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CU - Hypertensive emergencies; asthma
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T -Many; limited disruption of ANS
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Trimethaphan (MOA & PK)
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MOA - Reversibly inhibits ACh binding to nicotinic receptors
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PK - IV; quartenary amine; poorly/erratically absorbed after given orally
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Trimethaphan (CU & T)
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CU - Hypertensive emergencies; induce hypotension
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T -Many; limited disruption of ANS
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Mecamylamine (MOA & PK)
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MOA - Reversibly inhibits ACh binding to nicotinic receptors
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PK - PO; secondary amine; improved GI absorption and distribution to CNS
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Mecamylamine (CU & T)
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CU - Hypertensive emergencies; induce hypotension; electroconvulsive adjunctive aides; smoking cessation
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T -Many; limited disruption of ANS
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