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21 Cards in this Set
- Front
- Back
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The transmitter acting on NMDA receptors
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Glutamate
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The ion channel on which GABA acts
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Chloride channel (GABAa)
(GABAb metabotropic are linked to K channels) |
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The effect of the transmitter in the projection from the subthalamic
nucleus to the globus pallidus internal segment |
Excitatory via glutamergic connectiosn
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The type of receptor at the skeletal neuromuscular junction
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nAchR
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The transmitter in the iris which causes constriction of the pupil
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Acetyl Choline on Muscarinic receptors
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Anxiolytic drugs target
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Benzodiazepines (promote GABAa receptor efficiency)
SSRI prevent serotonin re uptake |
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Diazepam is used to treat acute status epilepsy
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benzodiazepine (enhances GABAa) true (less so for long term conditions)
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Drugs which reduce 5-HT action are a main treatment for depression
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False (SSRI such as fluoxetine are used for depression and increase 5HT action)
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Drugs which potentiate GABA action are used as anxiolytics
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true benzodiazpeines can be used as anxioltics
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Dopamine agonists are anti-psychotic
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False - Dopamine antagonists are anti psychotics
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Dopamine agonists help control the bradykinesia in Parkinsonism
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True- can do by increasing dopamine action in striatum mimicking SNpc action
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Serotonin reuptake inhibitors (SSRIs) are anti-epileptic
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False- used in anxiety and depression
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Lithium is anti-depressant
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True- enters via Na channels and capable of regulating many neuronal enzymes such as adenylate cyclase and PIP
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Barbiturates act on the GABA A chloride channel
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true but also block AMPA
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Dopamine antagonists are anti-psychotic
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True
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Dopamine antagonists control the tremor in Parkinsonism
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False
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Carbamazepine can be used in the chronic treatment of epilepsy
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TRUE- Stabalises Na Channel inactive state, may have function on upegulating GABA
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The principal transmitter produced by the raphe nuclei of the brainstem
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serotonin
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The effect of the principal transmitter in the projection from the striatum to
the globus pallidus internal segment |
inhibition (GABA system)
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The receptor involved in hippocampal long term potentiation
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NMDA is coinicidence detector
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The transmitter acting on AMPA/kainate receptor
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Glutamate
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