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18 Cards in this Set
- Front
- Back
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three nuclei of the basal ganglia
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caudate, putamen, and globus pallidus
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corpus striatum
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contains two nuclei, caudate and putamen. input zone for basal ganglia
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receiving neurons in the cotricostriatal pathway
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medium spiny neurons
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corticostriatal pathway
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pathways from different parts of the brain to the corpus striatum
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where does the caudate part of the basal ganglia receive input from?
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the multimodal association cortices and motor areas from frontal lobe that control eye movements
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where does the putamen part of the basal ganglia receive its input from?
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primary and secondary somatic sensory cortex,visual cortex, premort and motor cortex, and auditory association areas
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where do dopamanergic inputs to the basal ganglia come from?
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substantia nigra pars compacta
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What are inhibitory synapses on the medium spiny neurons?
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interneurons and thalamic neurons
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putamen nuclei
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fires in anticipation of body movements
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caudate nuclei
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fire in anticipation of eye movements
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major output neurons for the basal ganglia
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substantia nigra pars reticulata and the globus pallidus
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hemiballismus
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violent involuntary movements of the limbs. defects in subthalamic nucleus of the contralateral side of the movements.
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type D1 receptors
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receptors for spiny neurons that project to the internal globus pallidus (excitatory)
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type D2 receptors
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receptors for spiny neurons that project to the external globus pallidus (inhibitory)
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parkinson's disease
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due to degeneration of dopaminergic neurons of the substantia nigra pars compacta.
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huntingon's disease
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progressive deterioration of the caudate and the putamen. leads to a movement disorder consisting of rapid jerky motions with no clear purpose
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occularmotor loop
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loop in basal ganglia that modulates gaze
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limbic loop
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loop in basal ganglia that regulates emotional behavior and motivation
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