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20 Cards in this Set
- Front
- Back
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What is the difference between Neurosurgeon and a neurologist?
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Neurosurgeon operates on the brain and a neurologist does diagnostic work.
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If I wanted to see if X caused C how would I test the hypothesis?
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I would destroy X with the hopes that C would be destroyed.
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Why are rats used in surgeries?
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They are tough, bred to be calm, and there's a lot of information about rats.
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Why are rats preferred instead of mice?
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Mice escape easily, have smaller brains, and 80-90% of mice has an odor.
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Why do neuropsychologists operate on cats?
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Narrow range of sizes
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What's the significance that the same surgery on different animals results in different outcomes?
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It shows evolution.
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What are the down falls of operating on a small primate?
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Surgery is more difficult and death rate is higher
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What is the controversy about using chimps? What will some neuropsychologists use instead?
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They claim chimps are sentient beings (conscious).
Some will use baboons instead. |
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How do you apply research and surgeries done on animals to people?
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Find as many people that has had ONLY that part of the brain destroyed.
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What are the Research and Surgery steps? (in order)
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1. Select animal
2. Pretesting 3. Procedure 4. Give animal liquids and nutrients back 5. Post-test 6. Humanely terminate the subject 7. "Doing Brains" 8. Draw Conclusions |
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What are the questions you need to ask when pretesting?
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What can the animal do and how well?
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What happens in the procedure?
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Anesthesia and extirpation
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What does extirpation mean?
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removal
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What are the types of extirpation? And what are the differences?
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Ablation and lesion. Ablation cuts out a part of the brain using scalpels and spoon-like tool. Lesions uses a stereotaxic instrument to burn a part of the brain.
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What is a Stereoplastic Atlas?
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A map of the brain of a specific animal
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What coordinates do you need for the Stereoplastic Atlas?
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1) Vertically, 2) horizontally, 3) Depth
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Where do you look to find the chemical amount to give the animal for anesthesia?
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The MERC manual
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What are the types of injection of anesthesia? And define.
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Sub-q: below skin
IM - inter or intra muscular IC - intercardial (in the heart) IP - intra paratneal - cavity that holds your intestines |
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When is intra paratneal (IP) used for sedation?
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Rabies
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Steps of doing brains?
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Perfuse (wash out blood and preserve with a saline solution), decapation, need to get brain out, put brain in a cube of a waxy substance and then into a jar, slice brain with a microtome, and then a "histology" or microscopic analysis
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