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80 Cards in this Set

  • Front
  • Back

narcotine

exo organic opium alkaloid

papavernie

exo organic opium alkaloid

morphine

exo organic opium alkaloid

codeine

exo organic opium alkaloid

thebain

exo organic opium alkaloid

oxymorphone

modified opiate


numorphon

diacetylmorphine

modified opiate


heroin

oxycodone

modified opiate


percodan oxycotin

hydrocodone

modified opiate


dilaudid

hydromorphone

modified opiate


vicodin

buprenophrine

synthetic opiates (piperidine andgesies)


buprenex


partial ago

methadone

synthetic opiates (piperidine andgesies)


dolophine



meperidine

synthetic opiates (piperidine andgesies)


demerol


trtment of addiction

propoxyphene

synthetic opiates (piperidine andgesies)


dorvone

fentanyl

synthetic opiates (piperidine andgesies)


short acting

sefentanil

synthetic opiates (piperidine andgesies)


short acting

nalaxone

opiate ant


overdose treatment

naltrexone

opiate ant


overdose treatment



diprenorphine

opiate ant


overdose treatment

withdrawal: early symptoms

watery eyes, runny nose, yawning no apetitie, anxiety, irritability, insomnia, rapid increase in AC activity

withdrawal: longer duration

tremors hallucinations, panic, chills, sweating, cramps, nasea wretching




high rate of recividism

major categories of controlled substances: stimulants

nicotine, caffeine, ephedrine, cocaine, amphetamines, designer drugs

major categories of controlled substances: depressants

ethanol, barbituates, BDZ, opiates, PCP, ketamine



major categories of controlled substances: hallucinogens/psychoactives

marijuana, hash, peyote, LSD, PCP/ketamine, psilocybin, DD(exstacy)

major categories of controlled substances: anabolic steroids

androgens

Drug enforcement: DEA (justice)

-federal


concentration on trafficking (international and interstate), diversion, elimination of foreign growers

Drug enforcement: ATF (treasurey)

-federal


concentration on domestic prodxn, growers, theoretical revenue source

DPS

- state


- involved all levels, including low level dealers and useres



Sheriff

-county


all levels including low level dealers and users



police

-local


- all levels inlcuding low level dealers and users

DEA: CSA

-controlled substances act


-title 2 of he comprehensive dug abuse prevention and contrl act of 1970 is the legal foundation of the gov. fight against abuse of drugs and other substances

Federal Drugs laws: how many schedules?

5

Federal drug laws: placed under schedules based on?

1. potential for abuse


2. Medical use


3.Safety/Dependence liability

Drug laws evauated: tabacco

formal scheduling: potential for abuse

create hazard for health/safety


not medical


-tabacco should be a felony drug


ethanol as well



federal drug schedules: 1

diactylmorphine, methaqualone, LSD, POT,MDMA,peyote, psilocybin-->lack of accepted safety

Federal drug schedules: 2

morphine, cocoaine, methadone, hydrocodone, methamphetamine, --> high potential for abuse, accepted med use, may lead to sever psychological or physical dependecne

federal drug laws: schedule 3

anabolic steroids, codeine/hydrocodone w tylenol, ketamine, ---> potential fo rabuse, currently accept med use, moderate/ decreased phys dependence

federal drug laws: schedule 4

BDZ's, anxiolytic drugs


decreased potential abuse, aceept med use, decerased psychological and physical dependence

federal drug laws: schedule 5

cough syrup with codein


decreased potential abuse, accepted med use, imited physical or psychological dependence

Variability in enforcement:


nicotine

stimulant


no sale to minors

Variability in enforcement:


cocaine

s2


stimulant

Variability in enforcement:


amphetamine

stimulant


s2

Variability in enforcement:


DD's

s1


stimulant

Variability in enforcement:


Etoh

depressant


no sale to minors

Variability in enforcement:


opiates

depressants


s1,s2,s3,s4,s5



Variability in enforcement:


barbituates

depressants


s2,s3,s4

Variability in enforcement:


BDZ

depressants


s4

Variability in enforcement: methaqualone

depressants


s1

Variability in enforcement: DD

psychedelic drugs


s1

Variability in enforcement: LSD

psychedlic drugs


s1

Variability in enforcement:peyote

psychedelic drugs


s1

Variability in enforcement: marijuana

psychedelic drugs


s1***


legal in WA, CO



Variability in enforcement: ketamine

psychedelic drug


s2

Variability in enforcement:PCP

psychedelic drug


s2

Variability in enforcement: anabolic steroids

s3

stimulants : health risks

sudden arythmias, cardiac failure, multiple organ failure, risk of acute psychosis w/ high doses/chronic use, percieved better performance not neccesarily tre

stimulants: physical dependence

strong risk, once developed physical withdrawal begins within hours after last does, withdrawal less severe than opiates

stimulants: psychological dependece

strong risk


high recividism for former users

opiates: health risks

over dose, potentially fatal coma, respiratory depresson, emesis, diseases from needle sharing, malnutrituion bc of decreased apetite,

opiates: physical dependence

strong risk, withdrawal within hs of last does

opiates: psychological dependence

reported for piperidine deritives (PCP, ketamins, etc) probable evidence for marijuana for some individuals

cannabis: health risks

smoking related respirator problems (can be more intesne then tabacco) mild immunosupression, stabalizes with chronic use, problems associated with adulterants, herbicides,

cannabis physical dependence

unsure

cannabis: psychological dependence

varies widely by individual, length of use, dosage

cannabis: clinical uses

antiemtic/nasea supresant (cemo)


relief o ocular pressure in glaucoma


treatment of lymphomas


anxiolytic

cannabinoid receptor: CB1

presyn in CNS, glial, also in lungs, testes, uteres`


Cannanbinoid receptor: CB2

immune sys, glial

cannanbinoid receptor:GPR55

nociceptors, vascular smooth muscle

anandamide

endo ago


CB1, CB2

noladin

endo ago


CB2. gpr55

THC

exo ago


CB1, CP2, GPR55

Dronabinol

exo ago


CB1, CB2, GPR55

Arvanil

specific ago


CB1

CB1, CB2 g prot

Gi

GPR55 g prot

G13

bp subunits CB1

inhibit VDCC, activate GIRKS

Gs

D1,D5


5HT 4,6,7


Beta 1,2,3


H2

Gi

D2,3,4


5HT1-A,B,D,E,F


Alpha 2A,B,C


H3,4


m2,4


mglur- 2,3,4,6,7,8



Gi/Go

GabaB



Gq

5HT2-A,B,C


alpha1-A,B,D


H1


M1,3,5


mglur1,5