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5 Cards in this Set
- Front
- Back
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What are the two classes of cholinomimetic agents?
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1) Cholinergic agonists 2) Cholinesterase inhibitors
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What is the mechanism by which cholinergic agonists act?
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Cholinergic agonists directly stimulate postsynaptic Ach receptors
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What is the mechanism by which cholinesterase inhibitors act?
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Cholinesterase inhibitors block the destruction of Ach by inhibiting ChE
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What are the peripheral effects of cholinomimetics?
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Eye: contraction/accommodation
Salivary glands: profuse, watery secretion Small/Large intestine: increased tone, sphincter relaxation Bladder: increased urination Muscle: contraction |
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The peripheral effects of cholinomimetics mimic the effects of
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parasympathetic stimulation or skeletal muscle stimulation.
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