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11 Cards in this Set
- Front
- Back
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organophosphate poisoning
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- cholinesterase-inhibitor
- both UMN, LMN - tx: atropine (anticholinergic), pralidoxine |
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lead poisoning sx?
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- low levels: ataxia, tremor
- chronic: decreased psychomotor development, MR - brain edema - deadly |
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cholinesterase inhibitors
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- pyridostigmine, physostigmine, edrophonium
- used as tx of myasthenia gravis |
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felt or paper factory worker with personality changes, tremor, ataxia
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- use of mercury => damage ot granular layer of cerebellum
- visual field constriction => calcarine cortex in occipital lobe |
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adults exposed to lead
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- e.g. drinking from ceramic
- bilateral neuropaties esp radial nerve => wrist drop - abd pain, constipation, anemia, basophilic stippling in erythrocyte precursors, gingival margin discoloration - tx: penicillamine |
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arsenic poisoning
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- tonic-clonic seizures, hemolysis, mucosal irritation, decreased DTR
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ergot
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- rye fungus => posterior columns => ataxia => decreased DTR, seizures, fasciculations, myoclonus
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manganese
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- seen in miners => parkinsonism
- neuronal loss in globus pallidus, putamne, caudate, hypothalamus, cerebellum |
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carbon monoxide poisoning
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- delayed neuro deterioration: extrapyramidal d/o, parkinsonian gait, bradykinesis
- classic: hypodensities in GP bilaterally |
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ciguatoxin
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- sx of temperature reversal
- produced by dinoflagellate => eaten by groupers => eaten by people |
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ionizing radiation
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- accelerated atherosclerosis => carotid stenosis => stroke
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