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18 Cards in this Set
- Front
- Back
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sx of lyme disease
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- erythema chronicum migrans, meningitis, arthralgia, facial weakness, optic neuritis, schwannoma VII
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which vitamin to give with TB meds?
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- when taking isoniazid give pyridoxine (B6)
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lyme radiculopathy
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- noncompressive sciatica => radating pain down leg
- lyme produces painful radiculopathy and neuropathy |
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complication of CN injury in lyme disease?
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- injury of CN => aberrant regeneration of CN, esp CN III
- e.g. facial twitching with blinking |
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knee reflex
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- need intact sensory to tendon and motor to muscle
- L2, L3 |
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factory worker with painless motor peripheral neuropathy
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- lead poisoning => often targets radial nerve => wrist drop
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other chemical poisonings?
- thallium - manganese - cyanide - mercury |
- thallium - painful sensory neuropathy, GI, seizures, stupor
- manganese: parkinsonism - cyanide: optic neuropathy - mercury: paresthesia peripheral neuropathy |
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29 y.o. woman with weakness in multiple muscles, no particular pattern, plexus, root?
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- DM => mononeuropathy multiplex => individual nerves are transiently disabled => takes weeks to months to recover
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anatomy of wrist drop:
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- radial nerve - posterior cord of brachial plexus
- know brachial plexus! |
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Friedreich disease associated with degeneration of? which chromosome? what other disease?
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- spinocerebellar, posterior columns, lateral corticospinal tracts, dorsal root
- Chromosome 9, but note that spinocerebellar degerneration is associated with chr 6 - DM |
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most common infection preceding GBS?
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- campy
- others: CMV, HIV, EBC |
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Fredeich's ataxia sx?
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- congenital abnormalities seen in early childhood: hyphoscoliosis, pes caus, gait difficulties
- later: visual loss 2/2 optic atrophy, syncope, vertigo, dysarthria |
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tx of severe GBS?
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- plasma exchange, IV Ig
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Parsonage Turner syndrome
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- aka brachial plexopathy
- familial AD or s/p vaccinations, viral illness - pain in shoulder => weakness => sensory loss |
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4 year old Jew with normal strength, hyporeflexic, decreased sensation, orthostatic, ulcerated cornea
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- familial dysautonomia or Riley Day disease
- small fiber neuropathy, sympathetic, parasympathetic => autonomic features |
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woman with sensory and motor deficitis in hands and feet, increased protein CSF
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- chronic inflammatory demyelinating polyenuropathy
- like GBS but hands and feet, slower - demyelination of nerve root => inflammation => increased CSF protiein |
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s/p meds => confusion, psychosis, abd pain, vomiting, weak, areflexic
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- acute intermittent porphyria
- 2/2 porphyrinogenic drugs e.g barbiturates, phenytoin, sulfonamide, estrogen - tx: IV hematin |
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dentist with worsening pins and needles? Lhermitte sign?
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- nitrous oxide poisoning
- Lhermitte: electrical pain down back on flexion of neck - also see megaloblastic anemia |
