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6 Cards in this Set

  • Front
  • Back

What is a seizure, and what is epilepsy?

A seizure is abnormal, paroxysmal, excessive discharge from CNS neurons. Epilepsy is recurrent, unprovoked seizures

What is the difference between generalized and focal (partial)

1. Generalized: involves the brain diffusely


2. Focal (partial): involves discrete area of the brain, implying a structural lesion

Describe the three different types of generalized seizures



1. tonic clonic - tonic phase (contractions, expiratory moan, cyanosis, pooling of secretion) lasts 10-20s, and clonic phase (relaxation) ~30s


2. Absence (petit mal) - transient lapse of consciousness without lapse of postural tone


3. myoclonic - sudden, brief contraction (found in infantile spasms and juvenile myoclonic epilepsy)

What are the features of a focal (partial) seizure? What makes them "complex"?

Focal seizures involve focused motor, sensory, or autonomic abnormalities. They are considered complex if the patient has a change in mental status (making it hard to differentiate complex focal from absence seizures, where focal have preceeding focal abnormalities)

How can you help to differentiate seizure from syncope?

1. aura - automatism or unusual behaviour vs. diaphoresis, nausea, tunnel vision


2. convulsions variable vs. <10s in syncope


3. post ictal state that can last greater than 30 mins


4. tongue biting and incontinence

What is the "ABCDE" pneumonic for causes of seizure?

Alcohol withdrawal/illicit drugs/meds (beta-lactams, buproprion, metronidazole, etc)


Brain tumor or penetrating trauma


Cerebrovascular disease, including subdural hematoma, hypertensive encephalopathy


Degenerative diseases of the CNS like alzheimers


Electrolyte abnormalities (hyponatremia) and metabolic (uremia/liver failure/hypoglycemia)