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55 Cards in this Set

  • Front
  • Back
2 equilibrium-related problems
vertigo
ataxia
vertigo means ___
2 kinds of vertigo are ___
sensation of spinning
peripheral
central
___ is always present with peripheral vertigo
nystagmus
nystagmus in peripheral vertigo is always ___
horizontal
nystagmus in central vertigo can be ___ and ___
bidirectional
vertical
hearing loss or tinnitus is primarily associated with ___ vertigo
peripheral
ataxia means ___
3 kinds of ataxia
motor incoordination not caused by muscle weakness
vestibular
cerebellar
sensory
___ (2) are present with vestibular ataxia, but not ___
vertigo
nystagmus
dysarthria
vestibular ataxia is ___ dependent
gravity
midline cerebellar lesions affect ___ (2)
posture
gait
hemispheric cerebellar lesions cause ___ (5)
ipsilateral hemiataxia
ipsilateral hypotonia
gaze deflection away from affected side
nystagmus
dysarthria
sensory ataxia is due to ___ lesion
proprioceptive afferent
Weber and Rinne tests distinguish between ___ and ___ hearing problems
sensorineural
conductive
in Weber test, tuning fork is held at ___
in sensorineural problem, sound is perceived as ___.
in conductive problem, sound is perceived as ___.
skull vertex
coming from healthy side
coming from affected side
in Rinne test, tuning fork is held at ___
in sensorineural problem ___.
in conductive problem ___.
mastoid process, then next to external auditory meatus
air conduction > bone conduction
bone conduction > air conduction
___ tremor is associated with cerebellar ataxia
intentional
benign positional vertigo is caused by ___. it is treated by ___
canalolithiasis (debris in endolymph)
repositioning (moving head to relocated debris)
meniere disease is caused by ___.
it presents with ___ (3).
it is treated with ___ such as ___ (2)
excess endolymph
vertigo
tinnitus
progressive hearing loss
diuretics
hydrochlorothiazide
triamterene
4 kinds of drugs used for acute vertigo
antihistamine
anticholinergic
benzodiazepine
sympathomimetics
3 antihistamines used in acute vertigo
meclizine
promethazine
dimenhydrinate
anticholinergic used for acute vertigo
scopolamine
benzo used for acute vertigo
diazepam
2 sympathomimetics used for acute vertigo
amphetamine
ephedrine
acute peripheral vestibulopathy presents with ___ and sometimes follows ___.
it is treated with ___.
vertigo
febrile illness
prednisone
otosclerosis is causd by immobililty of ___. it causes ___ hearing loss.
stapes
conductive
T/F: otosclerosis can cause vertigo
true
T/F: otosclerosis can cause sensorineural hearing loss
true
4 ototoxic medications
aminoglycosides
salicylates
cis platinum
quinine
5 causes of acute cerebellar dysfunction
drugs
Wernicke encephalopathy
vertebrobasilar ischemia
cerebellar hemorrhage
inflammation
4 kinds of drugs which cause cerebellar dysfunction
EtOH
sedatives
anticonvulsants
hallucinogens
____ is a hallucinogen associated with cerebellar dysfunction
PCP
___ is an anticonvulsant associated with cerebellar dysfunction
phenytoin
Wernicke encephalopathy is caused by ___ aka ___ deficiency.
thiamine
B1
triad of Wernicke encephalopathy
ataxia
ophthalmoplegia
confusion
5 brain regions affected by Wernicke encephalopathy
medial thalamic nuclei
mamillary bodies
periaqueductal grey
cerebellar vermis
CN nuclei
CN nuclei commonly affected by Wernicke encephalopathy
3
6
8
ataxia in Wernicke encephalopathy mostly affects ___
gait
tendon reflex missing in Wernicke encephalopathy
ankle jerk
tx for Wernicke encephalopathy
thiamine 100 mg IV
first sx of Wernicke encephalopathy to improve
ocular palsy
4 causes of vertebrobasilar ischemia
internal auditory a. occlusion
lateral medullary infarction
cerebellar hemorrhage
paramedian midbrain infarction
MANOVA
A statistical test for studies that have one or more independent variables and two or more dependent variables.
5 lateral medullary infarction sx
vertigo
dysphagia
ipsilateral Horner's syndrome
bilateral facial hypoesthesia
contralateral limb hypoesthesia
paramedian midbrain infarction results from occlusion of ___
it causes ___ syndrome
paramedian penetrating branches of basilar a.
Benedikt
brain areas affected by paramedian midbrain infarction
red nucleus
CN3 fibers
6 causes of chronic cerebellar dysfunction
MS
alcohol
phenytoin
hypothyroidism
paraneoplastic
genetic
___ cancers are associated with paraneoplastic cerebellar degeneration
lung (esp small cell)
ovarian
paraneoplastic cerebellar degeneration is a ___ condition caused by ___
autoimmune
cross reaction between tumor and purkinje cells
3 kinds of genetic cerebellar degeneration
AD
friedreich ataxia
ataxia telangiectasia
many AD causes of cerebellar degeneration are caused by ___
and therefore exhibit ___
trinucleotide repeat expansion
anticipation
friedreich ataxia is a ___ trait. it is caused by ___ in ___ gene.
it causes degeneration of ___ (3).
AR
trinucleotide repeat expansion
frataxin (chromosome 9)
spinocerebellar tracts
dorsal columns
peripheral nerves
friedreich ataxia presents between ages of ___ and ___.
patients eventually develop ___ and ___.
4
end of puberty
kyphoscoliosis
cardiomyopathy
effects of friedreich ataxia are similar to those of ___ deficiency
Vitamin E
ataxia telangiectasia is caused by ___
ATM mutation
top 4 cerebellar tumors IDOOF
mets
astrocytoma
medulloblastoma
schwannoma