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55 Cards in this Set
- Front
- Back
2 equilibrium-related problems
|
vertigo
ataxia |
|
vertigo means ___
2 kinds of vertigo are ___ |
sensation of spinning
peripheral central |
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___ is always present with peripheral vertigo
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nystagmus
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nystagmus in peripheral vertigo is always ___
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horizontal
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nystagmus in central vertigo can be ___ and ___
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bidirectional
vertical |
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hearing loss or tinnitus is primarily associated with ___ vertigo
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peripheral
|
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ataxia means ___
3 kinds of ataxia |
motor incoordination not caused by muscle weakness
vestibular cerebellar sensory |
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___ (2) are present with vestibular ataxia, but not ___
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vertigo
nystagmus dysarthria |
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vestibular ataxia is ___ dependent
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gravity
|
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midline cerebellar lesions affect ___ (2)
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posture
gait |
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hemispheric cerebellar lesions cause ___ (5)
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ipsilateral hemiataxia
ipsilateral hypotonia gaze deflection away from affected side nystagmus dysarthria |
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sensory ataxia is due to ___ lesion
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proprioceptive afferent
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Weber and Rinne tests distinguish between ___ and ___ hearing problems
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sensorineural
conductive |
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in Weber test, tuning fork is held at ___
in sensorineural problem, sound is perceived as ___. in conductive problem, sound is perceived as ___. |
skull vertex
coming from healthy side coming from affected side |
|
in Rinne test, tuning fork is held at ___
in sensorineural problem ___. in conductive problem ___. |
mastoid process, then next to external auditory meatus
air conduction > bone conduction bone conduction > air conduction |
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___ tremor is associated with cerebellar ataxia
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intentional
|
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benign positional vertigo is caused by ___. it is treated by ___
|
canalolithiasis (debris in endolymph)
repositioning (moving head to relocated debris) |
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meniere disease is caused by ___.
it presents with ___ (3). it is treated with ___ such as ___ (2) |
excess endolymph
vertigo tinnitus progressive hearing loss diuretics hydrochlorothiazide triamterene |
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4 kinds of drugs used for acute vertigo
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antihistamine
anticholinergic benzodiazepine sympathomimetics |
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3 antihistamines used in acute vertigo
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meclizine
promethazine dimenhydrinate |
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anticholinergic used for acute vertigo
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scopolamine
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benzo used for acute vertigo
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diazepam
|
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2 sympathomimetics used for acute vertigo
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amphetamine
ephedrine |
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acute peripheral vestibulopathy presents with ___ and sometimes follows ___.
it is treated with ___. |
vertigo
febrile illness prednisone |
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otosclerosis is causd by immobililty of ___. it causes ___ hearing loss.
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stapes
conductive |
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T/F: otosclerosis can cause vertigo
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true
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T/F: otosclerosis can cause sensorineural hearing loss
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true
|
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4 ototoxic medications
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aminoglycosides
salicylates cis platinum quinine |
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5 causes of acute cerebellar dysfunction
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drugs
Wernicke encephalopathy vertebrobasilar ischemia cerebellar hemorrhage inflammation |
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4 kinds of drugs which cause cerebellar dysfunction
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EtOH
sedatives anticonvulsants hallucinogens |
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____ is a hallucinogen associated with cerebellar dysfunction
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PCP
|
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___ is an anticonvulsant associated with cerebellar dysfunction
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phenytoin
|
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Wernicke encephalopathy is caused by ___ aka ___ deficiency.
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thiamine
B1 |
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triad of Wernicke encephalopathy
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ataxia
ophthalmoplegia confusion |
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5 brain regions affected by Wernicke encephalopathy
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medial thalamic nuclei
mamillary bodies periaqueductal grey cerebellar vermis CN nuclei |
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CN nuclei commonly affected by Wernicke encephalopathy
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3
6 8 |
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ataxia in Wernicke encephalopathy mostly affects ___
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gait
|
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tendon reflex missing in Wernicke encephalopathy
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ankle jerk
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tx for Wernicke encephalopathy
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thiamine 100 mg IV
|
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first sx of Wernicke encephalopathy to improve
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ocular palsy
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4 causes of vertebrobasilar ischemia
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internal auditory a. occlusion
lateral medullary infarction cerebellar hemorrhage paramedian midbrain infarction |
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MANOVA
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A statistical test for studies that have one or more independent variables and two or more dependent variables.
|
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5 lateral medullary infarction sx
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vertigo
dysphagia ipsilateral Horner's syndrome bilateral facial hypoesthesia contralateral limb hypoesthesia |
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paramedian midbrain infarction results from occlusion of ___
it causes ___ syndrome |
paramedian penetrating branches of basilar a.
Benedikt |
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brain areas affected by paramedian midbrain infarction
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red nucleus
CN3 fibers |
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6 causes of chronic cerebellar dysfunction
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MS
alcohol phenytoin hypothyroidism paraneoplastic genetic |
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___ cancers are associated with paraneoplastic cerebellar degeneration
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lung (esp small cell)
ovarian |
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paraneoplastic cerebellar degeneration is a ___ condition caused by ___
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autoimmune
cross reaction between tumor and purkinje cells |
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3 kinds of genetic cerebellar degeneration
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AD
friedreich ataxia ataxia telangiectasia |
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many AD causes of cerebellar degeneration are caused by ___
and therefore exhibit ___ |
trinucleotide repeat expansion
anticipation |
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friedreich ataxia is a ___ trait. it is caused by ___ in ___ gene.
it causes degeneration of ___ (3). |
AR
trinucleotide repeat expansion frataxin (chromosome 9) spinocerebellar tracts dorsal columns peripheral nerves |
|
friedreich ataxia presents between ages of ___ and ___.
patients eventually develop ___ and ___. |
4
end of puberty kyphoscoliosis cardiomyopathy |
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effects of friedreich ataxia are similar to those of ___ deficiency
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Vitamin E
|
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ataxia telangiectasia is caused by ___
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ATM mutation
|
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top 4 cerebellar tumors IDOOF
|
mets
astrocytoma medulloblastoma schwannoma |