Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key


Play button


Play button




Click to flip

11 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
Name the drug classes used for Parkinson's disease.
Dopamine agonists, MAO inhibitors, Antimuscarinics, COMT inhibitors
Remember B/A/L/S/A
Name the Dopamine agonists.
L-dopa/carbidopa, bromocriptine (an ergot alkaloid and partial dopamine agonist), pramipexole, ropinirole, amantadine (enhances dopamine release).
Name the MAO inhibitors.
Seleginline (selective MAO type B inhibitor)
Name the antimuscarinics
Benztropine (imporves tremor and rigidity but has little effect on bradykinesia)
Name the COMT inhibitors
Entacapone, tolcapone (adjunct to levodopa)
b/c levodopa broken down in peripery by comt-leaving more for brain
What is the mechanism L-dopa (levodopa)/carbidopa?
increaseslevel of dopamine in brain. L-dopa can cross bloodbrain barrier and is converted by dopa decarboxylase in the CNS to dopamine.
What is the clinical use for L-dopa?
The toxicity of L-dopa implications are?
Arrhythmias from peripheral conversion to dopamine. Cardidopa, a periperal decarboxylase inhibitor, is given with L-dopa in order to increase the bioavailability of L-dopa in the braiin and to limit peripheral side effects.
Dyskinesias also occurs.
What is the mechanism for Selegiline (deprenyl)?
Selectively inhibits MAO-B, thereby increasing the availablity of dopamine.
What is the clinical use of deprenyl?
Adjunctive agent to L-dopa in treatment of Parkinson's disease.
Also called Selegiline
What are the toxicity implications?
May enhance adverse effects of L-dopa.