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17 Cards in this Set
- Front
- Back
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What are the most common symptoms of ADHD?
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Impulsiveness: a person who acts quickly without thinking things through.
Hyperactivity: a person who is unable to sit still. Inattention: a person who daydreams or seems to be in another world. |
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ADHD
Name the stimulants |
Methylphenidate (Ritalin)
Amphetamines d-amphetamine (Dexedrine) mixed amphetamines (Adderal) Pemoline (Cylert) not commonly used due to hepatotoxicity. |
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ADHD
Name the nonstimulants |
Atomoxetine
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Who am I?
It increase the level of dopamine and norepinephrine in the brain by blocking the dopamine transporter (DAT) and stimulating the release of these neurotransmitters. It has a rapid onset of action. Common adverse effects includes psychosis, weight loss and palpitations. High potential for abuse. |
Methylphenidate
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Who am I?
It acts by increasing levels of norepinephrine, serotonin, and dopamine in the brain. It has a rapid onset of action. Common adverse effects includes anorexia, weight loss and irritability. Risk for sudden death in patients with structural cardiac abnormalities. High potential for abuse. |
Amphetamine
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Who am I?
It is a selective norepinephrine (NE) reuptake inhibitor. Latency to onset for clinically effects. Less abuse potential. It increased the risk of suicidal ideation in children or adolescents with ADHD. |
Atomoxetine (Strattera)
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____________ involves loss of acetylcholine secreting neurons from hippocampus and cortex.
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Alzheimer’s disease
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Alzheimer's Disease
____________: Do not reverse disease process Provide only short-term cognitive improvement Do not alter disease progression |
Cholinesterase inhibitors
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What are the ACh E inhibitors?
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Tacrine (Cognex) - Hepatotoxicity Donepezil (Aricept) Rivastigmine (Exelon) Galantamine (Reminyl)
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What is a NMDA antagonist?
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Memantine
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What causes Huntington's disease?
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It is due to degeneration of GABA neurons in the striatum.
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Huntington's Disease
Treatment is mainly symptomatic by antipsychotics like __________. |
haloperidol
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Huntington's Disease
_________ help in reducing excessive movements. |
GABA facilitatory drugs like benzodiazepine
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Amyotrophic Lateral Sclerosis also known as __________
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Lou Gehrig disease.
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Lou Gehrig disease
It is a progressive disorder of the __________ characterized by muscle wasting and respiratory failure. |
motor neurons
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Amyotrophic Lateral Sclerosis
There is a defect in the _________, an enzyme that scavenges super oxide radicals. |
super oxide mutase
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Who am I?
Amyotrophic Lateral Sclerosis I block the sodium channel and decrease the release of glutamate thus protects the motor neurons. |
Riluzole
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