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75 Cards in this Set

  • Front
  • Back
what fibers cross at the optic chiasm
Nasal fibers
what fibers do the optic tract contain
ipsilateral Temporal retina
contralateral Nasal retina
axons and information from both eyes
where is the primary visual cortex located
brodmann's area 17
surrounds Calcarine Fissure
on the medial surface of the Occipital Lobe
what is the LINGUAL gyrus and what is the path leading to it
superior visual field
inferior retina
LGN
TEMPORAL LOBE
lingual gyrus
what is the CUNEUS gyrus and what is the path leading to it
inferior visual field
superior retina
LGN
PARIETAL LOBE
cuneus gyrus
right optic nerve lesion will result in...
monocular blindness (OD)
APD (OD)
optic chiasm lesion at midline will result in...
bitemporal hemianopia (peripheral vision loss)
destroys crossing nasal fibers

major cause:
pituitary gland tumor
aneurysm in anterior cerebral or anterior communicating artery
right lateral margin of optic chiasm lesion will result in...
nasal hemianopia (OD)

major cause: aneurysm or atherosclerosis of ICA
right optic tract lesion will result in...
left homonymous hemianopia
lesion of what will result in a RIGHT HOMONYMOUS HEMIANOPIA
right optic tract
right LGN
ALL visual radiation
entire right side of primary visual cortex
right internal capsule
lesion in OD visual radiation fibers in Meyer's loop pathway will result in
left superior homonymous quadrantanopia
due to lesion of temporal lobe, enlargement of lateral ventricle tumors
lesions to visual radiation fibers running through parietal lobe will result in...
left inferior homonymous quadrantanopia
lesion in right primary visual cortex will result in...
left homonymous hemianopia
left homonymous hemianopia with macular sparring

major cause:
posterior cerebral artery damage
what causes macular sparing in right primary visual cortex lesions
collateral circulation of middle cerebral artery
what common with a blow to the back of the head
bilateral central scotoma
loss of macular vision
which artery supplies blood to the primary visual cortex
POSTERIOR CEREBRAL ARTERY
CALCARINE BRANCHES
collateral circulation from MIDDLE CEREBRAL ARTERY in case of occlusion of posterior cerebral arteries
what is the corticospinal tract
precentral gyrus
internal capsule
crus cerebri
through pyramids
Lateral Corticospinal Tract cross at caudal medulla (85%)
Ventral Corticospinal Tract cross at level of the spinal cord (15%)
what are the 5 extrapyramidal upper motor neurons (contra, ips, or bi)
Rubrospinal (contra)
Pontine Reticulospinal (ipsi)
Medullary Reticulospinal (ipsi)
Lateral Vestibulospinal (ipsi)
Medial Vestibulospinal (bi)
what is the corpus striatum
1.caudate nucleus
2.putamen
3.globus pallidus

(1&2=striatum)
(2&3)=lenticular nucleus
degeneration of the...results in Parkinson's Disease
substantia nigra
*largest nucleus in the midbrain
what is the main circuit of the basal ganglia
Cerebral cortex
Striatum
Globus Pallidus
Thalamus
*back to the Cerebral Cortex
how does the basal ganglia contribute to the motor control
basal ganglia DO NOT directly affect the motor neurons
basal ganglia influence motor control INDIRECTLY by modifying the output of the descending fibers from the cerebral cortex
what is the main circuit of the basal ganglia
Cerebral cortex
Striatum
Globus Pallidus
Thalamus
*back to the Cerebral Cortex
how does the basal ganglia contribute to the motor control
basal ganglia DO NOT directly affect the motor neurons
basal ganglia influence motor control INDIRECTLY by modifying the output of the descending fibers from the cerebral cortex
what is the pathway of the cerebellum
1. fibers from SC and brainstem enter and synapse in both cerebellar deep nuclei and cerebellar cortex
2. Purkinje cells in the cortex send axons to the deep nuclei, modulating the output of the nuclei
3. deep nuclei send fibers out of the cerebellum to the brainstem and thalamus
how does the basal ganglia inhibit movement
putamen
GP (external)
subthalamus
GP (internal)
what pathway does the basal ganglia take to facilitate movement
putamen
GP (internal) and substantia nigra
progressive supranuclear palsy
associated with parkinson's
supranuclear ophthalmoplegia (downward gaze paresis, spreads to other eye muscles)
C&S Huntington's Chorea
C: autosomal dominant movement disorder, mid 30s
chromosome 4

S: chorea
dementia
impaired saccades
Wilson's disease
C: autosomal recessive movement disorder
chromosome 13
copper metabolism defect

kayser-fleischer ring on outer margin of cornea
acoustic neuroma
CN VIII tumor
damage to cerebellopontine angle or internal acoustic meatus

unilateral hearing loss and tinnitus (ringing/buzzing)
facial weakness/loss of corneal reflex
ipsilateral loss of pain and temp.
what are the two components of the vestibulocochlear nerve (CN VIII)
auditory: from cochlea
vestibular: balance from semicircular canals
what acts as proprioceptors in ear and where are they located
hair cells
1.macula uticuli/macula sacculi (linear/posture)
2.cristae amullaris (angular/maintains balance)
what is the difference between nerve and conductive deafness
1. conductive: physical obstruction of sound waves from getting into the ear (inflammation, foreign body, ear wax, etc)
2. disease of cochlea (hair cells), cochlear nerve (acoustic neuroma), cochlear nuclei in the medulla

(unilateral damage to the peripheral portion results in significant IPSILATERAL hearing loss)
what is the degree of hearing loss with a central portion? why?
minor hearing loss
pass the cochlear nuclei the information ascends BILATERALLY to the cortex

difficulty in locating direction of the source of sounds and in understanding speech in areas of high background noise.
auditory pathway (peripheral portion)
external ear
external auditory meatus
tympanic membrane
middle ear bony ossicles
inner ear fluid

organ of corti (hair cells)
cochlear division (CN VIII)
cochlear nuclei in rostral medulla
auditory pathway (central portion)
after bifurcation @ cochlear nucleus

lateral lemniscus (X and unX)
inferior colliculus (midbrain)
inferior brachium (axons of inf. colliculus)
MGN of thalamus
auditory radiation (axons MGN)
transverse termporal gyrus in temporal lobe (41,42)
what is the difference between nerve and conductive deafness
1. conductive: physical obstruction of sound waves from getting into the ear (inflammation, foreign body, ear wax, etc)
2. disease of cochlea (hair cells), cochlear nerve (acoustic neuroma), cochlear nuclei in the medulla

(unilateral damage to the peripheral portion results in significant IPSILATERAL hearing loss)
what is the degree of hearing loss with a central portion? why?
minor hearing loss
pass the cochlear nuclei the information ascends BILATERALLY to the cortex

difficulty in locating direction of the source of sounds and in understanding speech in areas of high background noise.
auditory pathway (peripheral portion)
external ear
external auditory meatus
tympanic membrane
middle ear bony ossicles
inner ear fluid

organ of corti (hair cells)
cochlear division (CN VIII)
cochlear nuclei in rostral medulla
auditory pathway (central portion)
after bifurcation @ cochlear nucleus

lateral lemniscus (X and unX)
inferior colliculus (midbrain)
inferior brachium (axons of inf. colliculus)
MGN of thalamus
auditory radiation (axons MGN)
transverse termporal gyrus in temporal lobe (41,42)
rinne's test
stem of tuning fork held at mastoid process until no longer heard, then held in from of ear.

normal: AC better than BC (but hears both)
conductive: BC better than AC
nerve: AC better than BC in impaired ear
weber's test
stem of tuning fork held at vertex of the head, ask patient which ear is better

Normal: EQUAL
Conductive: better in ear with heading deficit
Nerve: better in ear w/o hearing deficit
where is the first synapse of the olfactory system
OLFACTORY BULB
NOT THALAMUS!!!!

IPSILATERAL
olfactory pathway
olfactory mucosa (chemoreceptors)
CN I
olfactory bulb
olfactory tract

then splits to:
lateral olfactory area (primary olfactory cortex, entorhinal cortex, amygala)
medial olfactory area: septal area

connected by anterior commissure
what is the two halves of the olfactory pathway connected by
anterior commissure
what is olfactory hallucinations? anosmia?
1.seizures of the temporal lobe
lesions near the lateral olfactory area (uncus, entorhinal cortex, amygdala)
2. loss of smell (head injuries damage CN I)
ossicles consist of
malleus
incus
stapes
chorea
rapid, jerky movements
athetosis
slow, writhing movements, snake-like
dystonia
slow, sustaining contractions of head and trunk
ballism
violent flinging movements of limbs
input/output to the cerebrocerebellum (motor planning)
input: contralateral cerebral cortex, indirectly via the pons

output: (contralateral) red nucleus projects to thalamus, (contralateral) thalamus relays to to cortex
CEREBELLUM controls the ... side of the body whereas the CEREBRAL CORTEX controls the ... side of the body
Cerebellum: IPSILATERAL
Cerebral Cortex: contralateral
tonsils of the cerebellum can herniate through which foramen?
MAGNUM FORAMEN
Arnold-Chiari Phenomenon
1.blockage of the flow of CSF from 4th ventricle...hydrocephlus
2.spina bifida
3.pressure on cerebellum and medulla oblongata (CN 9,10,11,12)
basal ganglia disorders v.s. cerebellar disorders (in respects to movement)
BG: UNintentional
Cerebellar: INTENTIONAL
vestibular nuclei projects to...via which pathway
1.cerebellum: direct
2.cerebral cortex: vestibulothalamic tract
3.spinal cord: lateral (ipsi) & medial (bi) vestibulospinal
4.gaze center and OMN: ascending portion of MLF
what are the symptoms of damaged vestibular system
1.vertigo: whirling surroundings
2.nystagmus: twitch of eye
3.loss of balance
doll's eye phenomenon
testing the integrity of the VESTIBULO-OCULAR REFLEX in an UNCONSCIOUS patient.
caloric test
integrity of the vestibular system can be assessed by triggering a nystagmus (head angled 30 degrees)
what are the subdivisions of the MIDBRAIN
1.Tectum (superior/inferior colliculus)
2.Cerebral Peduncle (tegmentum, substantia nigra, crus cerebri)
3.Cerebral Aqueduct
what nucleuses are associated with the midbrain
edinger-westphal (behind o.motor)
oculomotor (s. colliculus)
trochlear (inf. colliculus)
weber's syndrome
alternating oculomotor hemiplegia
damage to ipsilateral CN3 and contralateral Pyramidal Tract

cause: aneurysm of posterior cerebral antery
lateral gaze center
located in the abducens nucleus in the pons

1.LMN portion of the abducens nucleus innervates IPSI lateral rectus
2.Interneuron portion via axons travel in MLF activate contralateral O.Motor nucleus to Medial Rectus
internuclear ophthalmoplegia
damage: bilateral to the MLF

1.inability to adduct eye during lateral gaze to either side
2.Nystagmus
Parinaud's Syndrome
damage: compression of dorsal midbrain near the vertical gaze center
cause: pinealoma

inability to raise eyes above the horizontal plane
Pupillary Light Reflex Pathway
light
retina
optic nerve
optic chiasm
optic tract
PRETECTAL NUCLEI
BOTH Edinger-Westphal Nuclei
Preganglionic Parasympathetic nerve fibers in CN3
Ciliary Ganglia
Postganglionic parasympathetic nerve fibers
Sphincter pupillae muscles

CONSTRICTION
Argyll-Robertson pupil
Pupil: NO CONSTRICTION w/ Light

bilateral damage of pretectal area (syphilis)
pupils CAN constrict during ACCOMODATION (different pathway)
Accomodation of the EYE (PATHWAY)
Near Object
Retina
Optic Nerve
Optic Chiasm
Optic Tract
Lateral Geniculate Body
Optic Radiation
Visual Cortex
Edinger-Westphal
Ciliary Ganglion
CONSTRICTION
what is the largest projection to the HYPOTHALAMUS
FORNIX
what is the most common site for a stroke
internal capsule
what pathway corresponds with the suprachiasmatic nucleus
retinohypothalamic tract
which stages of sleep are the most restorative
3 and 4
what is part of the hippocampal formation? regeneration?
dentate gyrus*
subiculum
hippocampus

*regenerate