Neuro Shelf- Degenerative Diseases

Front 1

Disease of Cerebral Cortex-
Autoimmune axon demyelination of the CNS

Mnemonic: SIN
Slurred speech
Incontinence (bowl)/Intention Tremor
Nystagmus- loss vision in one eye

Back 1

Multiple Sclerosis
CNS - Bowl/Vision/ Speech

Front 2

Disease of Cerebral Cortex-
auto-immune Axon demyelination of the PNS - loss of deep tendon reflexes - hyporeflexia - INCREASED PROTEIN IN CSF

Back 2

Gullian barre
PNS - increase CSF Protein

Front 3

Disease of Cerebral Cortex-

Decreased stimulation of motor cortex by basal ganglia. Low Dopamine - restin tremor- hypokinetic

Back 3

Parkinson's disease-
Substanitia Nigra -

Front 4

Disease of Cerebral Cortex-
Degeneration of Caudate nucleus-LOSS OF GABAnergic NEURONS!!! Enlarged Lateral Ventricles-

Back 4

Huntington's Chorea
HYPERKINETIC = LOSS GABAnergic

(Dance link movements- Caudate -

Front 5

Disease of Cerebral Cortex-
DEMENTIA!!! PRION!!!- Spongiformcortex -
Rapidly Progressive - months-

Back 5

CJD =
Creutzfelt-Jakob DEMENTIA Disease-

Front 6

Disease of Cerebral Cortex-
Parkinson's + dementia + Hallucinations ->

Back 6

Lewy body dementia-

And remember CJD - is a prion disease which give DEMENTIA

Front 7

Disease of Cerebral Cortex-
#1 cause of DEMENTIA - Elderly People -
related to Downs synrome -
can cause intracranial hemhorraging

Back 7

Alzheimer's Disease

Front 8

LMN and UMN disease -

Defect in SUPEROXIDE - Flaccid paralysis at lesion and spastic below lesion -

Back 8

ALS - Lou Gherrig

Front 9

LMN disease - transmitted from stool - Headache - Fever- nausea - slight elevated Protein in CSF (viral)

Back 9

Poliomyelitis

Front 10

Degenerative Disorder-
Floppy Baby + LMN + dead at 7 months

Back 10

Werdnig Hoffmann disease - infantile spinal muscular atrophy