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17 Cards in this Set
- Front
- Back
Halothane
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- inhaled general anesthetics
- bad CV depression and rare hepatitis - low blood solubility |
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Isoflurane
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- inhaled general anesthetics
- fewere SE's than halothane - halogenated methyl ethyl ether, clear, nonflammable, pungent, very potent - big F/B |
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Desflurane
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- inhaled general anesthetics
- fewere SE's than halothane – a fluorinated methyl ethyl ether, very quick induction and recovery - irritating to lungs so don’t use w/ COPD |
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Sevoflurane
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- inhaled general anesthetics
- fewere SE's than halothane – fluorinated methyl ethyl ether, quick induction/recovery - pleasant to inhale so use for kids - big F/B - makes compound A |
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enflurane
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- inhaled general anesthetics
- fewere SE's than halothane |
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methoxyflurane
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- inhaled general anesthetics
- high blood solubility - nephrotox |
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Compound A
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- made when Sevoflurane interacts w/ CO2 absorbant soda lime
- a potential nephrotoxin – need fresh gas flows of ≥ 2 L/min w/ sevoflurane |
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dantrolene
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use in pts w/ malignant hyperthermia to block Ca release from SR
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Barbs that are injectable anesthetics as adjuvants to inhaled
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thiopental, methohexital, & thiamylal
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Propofol
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- injectable anesthetic as adjuvant to inhaled
- pharmacology similar to thiopental - causes marked decrease in systemic BP and is bad for pts w/ poor CV fcn - use for short cases w/ same day discharge – drips also used in ICU for ventilation tolerance |
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dexmedetomidine
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- injectable anesthetic as adjuvant to inhaled
- α2-adrenergic agonist - used like propofol |
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Etomidate
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- injectable anesthetic as adjuvant to inhaled
- carboxymethylated imidazole – for rapid induction, unconscious in secs and recovery in 3-5 min – little hypotension, so good alternative to propofol/thiopental in CV disease |
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Benzo's that are injectable anesthetics as adjuvants to inhaled
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Midazolam (or less-frequently diazepam or lorazepam) for short dental and med procedures, and inducing anterograde amnesia
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Ketamine
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- like PCP – NMDA glutamate R’s
- causes cataleptic state of dissociative anesthesia - CV stimulant - use in hypovolemic shock - Postop psychomimetic rxn - often given w/ benzo like midazolam, esps in peds |
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opoids that are injectable anesthetics as adjuvants to inhaled
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morphine, meperidine, fentanyl, sufentanil, alfentanil, and remifentanil (all μ’s)
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Fentanyl analogs
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- short-acting alfentanil
- ultra-short-acting remifentanil - both used for short surgical procedures or painful activities that need little analgesia post-op |
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Fentanyl w/ droperidol
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- opiod and potent ASY
- can make neuroleptic analgesia, conscious state of analgesia and amnesia – Adding 65% N2O to mix makes you unconsciousness - recently black boxed for prolonged QT |