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16 Cards in this Set

  • Front
  • Back
what nucleus of the thalamus does the basal ganglia primary output through?
Ventral Lateral
Key differences of basal ganglia vs. cerebellum
ipsilateral (vs. contra)
Cerebellum: coordination
-Ataxia
-excitatory output to thalamus
Basal Ganglia: planning and initiation
-dyskonesia
-inhibitory output to thalamus
Dyskosia types
Chorea:dance-like
Ballismus: flinging
tics: spasmidic movement or vocalization
Myoclonus: rapid muscular jerk
Rigidity
increased resistance to passive movement due to simultaneous contraction of extensors and flexors
Brake Hypothesis:
Stand still
brake voluntary movements of distal muscles while not braking (gating/allowing/releasing) activation of axial muscles controlling posture
Brake Hypothesis:
Initiate movement
brake postural control and release voluntary control of distal muscles
Striatum
caudate + putamen (+ nucleus accumbens)
-Embryologically and cytoarchitecturally (but not functionally) a single nucleus
Lentiform or lenticular nucleus
putamen + globus pallidus
-lens shape
Corpus striatum
(caudate & putamen) + globus pallidus
-telencephalic structures of the basal ganglia
Pedunculopontine nucleus
cholinergic diffuse modulatory system
regulates & relays basal ganglia activity through indirect pathway
pathways from the GPi to the thalamus:
Lenticular fasciculus (through IC)
Ansa Lenticularis (loops under)
-form thalamic fasciculus when they meet
modulation of direct and indirect pathways by SN pars compacta
both facilitate increased thalamic activity
Motor Channel
Input: BA 1-7 to Putamen
Output: VL/ VA thalamus
Thalamic Projection: supp., primary, premotor cortex (BA 4,6)
-controls medial and lateral motor systems
Oculomotor Channel
Input: Parietal and Prefrontal cortex to Body of Caudate
Output: VA/MD thalamus
Thalamic Projection: frontal eye fields and supplementary eye fields
-control eye movements, especially saccades
Prefrontal Channel
Input: Parietal and Premotor cortex to Head of Caudate
Output: VA/MD thalamus
Thalamic Projection: Prefrontal cortex
Limbic Channel
Input: Hippocampus, amygdala, temporal cortex to Nucleus Accumbens, Caudate and Putamen
Output: VA/MD thalamus
Thalamic Projection: Anterior Cingulate Gyrus, Orbital frontal cortex
-emotions, motivation, learning, memory