Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
16 Cards in this Set
- Front
- Back
what nucleus of the thalamus does the basal ganglia primary output through?
|
Ventral Lateral
|
|
Key differences of basal ganglia vs. cerebellum
|
ipsilateral (vs. contra)
Cerebellum: coordination -Ataxia -excitatory output to thalamus Basal Ganglia: planning and initiation -dyskonesia -inhibitory output to thalamus |
|
Dyskosia types
|
Chorea:dance-like
Ballismus: flinging tics: spasmidic movement or vocalization Myoclonus: rapid muscular jerk |
|
Rigidity
|
increased resistance to passive movement due to simultaneous contraction of extensors and flexors
|
|
Brake Hypothesis:
Stand still |
brake voluntary movements of distal muscles while not braking (gating/allowing/releasing) activation of axial muscles controlling posture
|
|
Brake Hypothesis:
Initiate movement |
brake postural control and release voluntary control of distal muscles
|
|
Striatum
|
caudate + putamen (+ nucleus accumbens)
-Embryologically and cytoarchitecturally (but not functionally) a single nucleus |
|
Lentiform or lenticular nucleus
|
putamen + globus pallidus
-lens shape |
|
Corpus striatum
|
(caudate & putamen) + globus pallidus
-telencephalic structures of the basal ganglia |
|
Pedunculopontine nucleus
|
cholinergic diffuse modulatory system
regulates & relays basal ganglia activity through indirect pathway |
|
pathways from the GPi to the thalamus:
|
Lenticular fasciculus (through IC)
Ansa Lenticularis (loops under) -form thalamic fasciculus when they meet |
|
modulation of direct and indirect pathways by SN pars compacta
|
both facilitate increased thalamic activity
|
|
Motor Channel
|
Input: BA 1-7 to Putamen
Output: VL/ VA thalamus Thalamic Projection: supp., primary, premotor cortex (BA 4,6) -controls medial and lateral motor systems |
|
Oculomotor Channel
|
Input: Parietal and Prefrontal cortex to Body of Caudate
Output: VA/MD thalamus Thalamic Projection: frontal eye fields and supplementary eye fields -control eye movements, especially saccades |
|
Prefrontal Channel
|
Input: Parietal and Premotor cortex to Head of Caudate
Output: VA/MD thalamus Thalamic Projection: Prefrontal cortex |
|
Limbic Channel
|
Input: Hippocampus, amygdala, temporal cortex to Nucleus Accumbens, Caudate and Putamen
Output: VA/MD thalamus Thalamic Projection: Anterior Cingulate Gyrus, Orbital frontal cortex -emotions, motivation, learning, memory |