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89 Cards in this Set

  • Front
  • Back

What innervates the central auditory pathway?

Auditory nerve (VIII)

What are the two streams of the Central Auditory Pathway?

Ventral and Dorsal



Recite the ventral central auditory pathway

auditory nerve --> synpase on ventral cochlear nucleus --> secondary afferent fibres split -> reach left AND right of superior olive in pons --> lateral lemniscus in pons --> inferior colliculi in midbrain--> medial geniculate nucleus in thalamus --> primary auditory cortex

What does the ventral auditory pathway do?

Determines the timing information about auditory input. Specifically, the biaural input at the superior olives gives us the interaural difference to determine timing and where sound is coming from.

What is this image?

What is this image?

ventral auditory pathway


bottom cut: pons --> superior olives and lateral lemniscus
middle cut: midbrain --> inferior colliculus 
top cut: brain: medial geniculate and primary auditory dortex

ventral auditory pathway




bottom cut: pons --> superior olives and lateral lemniscus


middle cut: midbrain --> inferior colliculus


top cut: brain: medial geniculate and primary auditory dortex

Recite the dorsal stream of the central auditory pathway

Auditory nerve (III) synapses on the dorsal cochlear nucleus --> the secondary afferents split--> go on the the lateral lemniscus in pons --> inferior colliculi (in midbrain) --> medial geniculate nuclei (in thalamus) --> primary auditory cortex for processing

What does the dorsal stream of the central auditory system do?

It determines sound quality (hence it doesn't go synapse on the superior olives)


Differences in frequencies determine different sound quality

Explain tonotopic organization

Sound frequency input that enters the central auditory pathway is organized exactly the same in the primary auditory cortex

Where are the low frequenices? In what region? Where are high frequenices? In what region?

What is this?

Where are the low frequenices? In what region? Where are high frequenices? In what region?

What is this?

-Cochlea
-Low is In middle in the apical region
High is in the outsie in the basal region
-The cochlea is where hairs pick up on the different frequenices

-Cochlea


-Low is In middle in the apical region


High is in the outsie in the basal region


-The cochlea is where hairs pick up on the different frequenices

Where is it?

Where is it?

Here it is!

Here it is!

Where does the auditory cortex lead to?

Superior temporal gyrus

What happens when there's damages to hair cells in one frequency range?

Neighboring hair cells pick up


What is tinnitus?

High frequency ringing of buzzing in the ears; brain could be manufacturing sounds to replace missing input

What is the heirarchy of executive functions you must go thru before a decision is made?

1. alertness


2. attention


3. memory


4. retrieval


5. decision making

What is the reticular formation?

A series of loosely arranged nuclei in the medulla, pons, and midbrain with ASCENDING and DESCENDING fibers

Where is the reticular formation located?

In the tegmentum--pons, medulla, and midbrain

What is the reticular formation involved with?

Proprioceptive, pain, and autonomic processes

Where do the descending fibers go?

-Originate in the reticular formation with nuclei in the medulla


-Travel downwards and connect to cerebellum, sensory system, and vital systems (like respiratory or cardiac)

What are the descending fibers of the reticular formation responsible for?

Sensory information but also autonomic functions such as heartbeat, respiration

Where do the ascending fibers go?

-Nuclei in pons and midbrain


-Connect to the thalamus, hypothalamus, and cortex

What does RAS stand for?

Reticular Activating System

What forms the RAS?

Ascending fibers from the reticular formation

What do ascending fibers of reticular fomraiton do?

-Form the RAS


-Involved in alertness, wakefullness, consciousness, and arousal

Lesion to the descending fibers of the reticular formation would lead to...?

DEATH

Lesion to the ascending fibers of the reticular formation would lead to...?

Lack of consciousness, coma, person still alive


Mike the Headless Chicken tbh

What stimulates the RAS?

Incorporates sensory information (visual, auditory, and pain stimuli)


Cognitive stimulsu

What would the removal of visual or auditory stimulus lead to in terms of alertness?

Drowsiness bc of a lack of sensory stimulation

How can irritants stimulate the RAS?

Trigeminal nerve



What are risk factors to RAS functioning?

Preterm birth, leads to deficits in sleep-wake cycle, arousal, an attention


Prenatal nicotine exposure leads to deficits in arousal and attention

Look at the recommendations of talking to someone in a coma

Coma not a passive state bc still EEG activity

What areas are implicated in attention? And how do they work with attention?

The 1) sensory system picks up on stimuli/environmental experiences and does preprocessing for attention, such that you can choose to attend to certain environmental stimuli. There is a 200 - 500 ms time period that this information is held onto




2) Prefrontal cortex - The prefrontal cortex makes the decision whether or not to pay attention to a stimulus picked up by the sensory system and allocates cognitive resources if the choice is made to attend

Types of Attention, describe, and give example

1. Focused


Turning head if someone opens door


2. Sustained


A security guard watching a monitor for hours on end


3. Selective


Studying in a busy coffee shop and focusing in on your notes amongst the noise


4. Alternating


Making flashcards and watching TV hehe

Who made the hierarchy of attention?

Scholberg & Mateer

What are the parts of memory? Describe each.

1. Encoding/Learning


Acquiring new information and forming neurological connections to aid in their retention


2. Retention/storage


Retaining information through organization and associations


3. Retrieval


Calling upon information using organization


Recognition and production (?)


4.Forgetting


Failure of memory

What are the stages of memory?

Sensory


Short Term


Long Term


Remote

What is sensory memory?

Part of memory that takes in sensory input; this input is there for about 1 or 2 seconds and the brain's prefrontal cortex makes a decision to attend to this information or not!

What is short term memory?

A few minutes


Can hold up to 7+/-2 chunks


Is aided by chunking (phone #s)


Basically holds information for a small amount of time

What is working memory?

A subset of Short Term Memory


Involves the visuospatial sketchpad, phonological loop, and central executive


A shifting window of attention that live processes

What is the phonological loop?

Part of the working memory, it is the auditory memory that is held onto for 0-30 seconds.

What is the visuospatial sketchpad?

Part of the working memory, it is the visual memory that is held onto for 0-30 seconds

What is the central executive?

Part of the working memory, it is the prefrontal cortex deciding whether or not to allocate resources and attention

What is the significance of chunking?

Chunking facilitates one's memory. Chunks vary in length and complexity. The STM can hold 7+/- 2 chunks but incr complexity allows for less chunks because pressure on cognitive load.

What is Long Term Memory (LTM)?

Long Term Memory is memory that is retained for longer than minutes

What are the two main types of LTM? (long term memory)

Explicit (declarative) and Implicity (Procedural)

What is explicit or declarative memory? What are the subtypes?

Explicit memory is memories you can consciously recall.


Episodic - remembering episodes of your life


Semantic - remembering general knowledge

What is implicit or procedural memory?

Memory you can't consciously recall. For example, Pavlov's dog (conditioned memory) or proecdures and skills (how to drive)

What is remote memory?

Memories from the distant past, intact in dementia

Types of retrieval

1. recall


2. recollection


3. recognition


4. relearning

What is recall? What are types?

Recall: regeneration of a memory


Free recall: regenerate memory without cue (essay question)


Cued recall: regenerate memory with cue

What is recollection?

The regeneration of a memory based off the logical organization of the brain's partial memories and cues

What is relearning?

If a stimulus is experienced again, forgetting and having to learn once again
(Studying abroad in Spain, forgetting conversational Spanish afterwards, but then remembering Spanish when you return)

What is organization's role in retrieval?

Need organization to encode and retrieve memories in a more efficient way


Memory is often organized into categories, as such, retrieval is easier if you stay within category (ex: if you're doing an animal naming activity, if you say cow, you would easily say other farm animals next such as pig, horse, etc. quicker than naming a non-farm animal)

What areas (anatomically) are involved in memory?

-hippocampus


-mammilary bodies


-prefrontal (medial and orbital surfaces)


-thalamus


What does the hippocampus do, in the context of memory? What happens if it incurs damage?

Contains long-term storage and processing


Damage leads to anterograde amnesia



What are the mammilary bodies?

They are the relay station for memory

What is the prefrontal cortex-medial and orbital surfaces? What happens if damaged

Organize memories


Damage leads to confabulation

What is the thalamus?

Serves as relay station for sensory memory, connects to thalamus

What is confabulation?

Stringing together memory in an unorganized way, false retelling without consciously decieving someone; misinterpreted or distorted memory

What is repetition's role in memory?

-Repetition can strengthen memory, because "retelling" a story will strengthen neurological connections over time.


-Others argue that repetition can threaten the integrity of a memory. By retelling a story, pieces of memory could be merged together, producing a false narrative or certain phrasing can shift certain nuances in memory by extension. Basically, memory is more vulnerable to changes as you pull it out

Explain storage in memory

Storage in memory is not all in one place and instead scattered, it's probably organized by associative areas

What is the circuit of Papez?

Neural circuit


Subset of limbic system interconnections


Leads to eventual memory consolidation

What is the flow of the circuit of Papez?

Fornix --> move anteriorally and medially until at mammilary bodies --> from the mammilary bodies, go to anterior thalamic nuclei (in thalamus) via the mammilothalamic tract --> from the anterior thalamic nuclei --> internal capsule --> cingulate gyrus --> moves posteriorly along to parahippocampal gyrus via the entorhinal cortex --> hippocampus --> MEMORY CONSOLIDATED

Describe characteristics of amnesia

(-) consolidation of memories and (-) retrieval


Different types of memory affected differently, either can't recall old memories or can't form new ones


STM in tact


Effects episodic memory most


Caused by damaged to medial temporal lobes and hippocampus

Types of amnesia

retrograde


anterograde


global


post-traumatic

Causes of amnesia?

Stroke, TBI, Infection, Alcoholism,

What are the areas that form the neurological basis of language?

-primary auditory cortex


-Wernicke's


-Angular gyrus


-Arcuate fasiculus


-Broca's


-Supramarginal gyrus


-primary motor


-corpus caollosum


-subcortical areas

Primary auditory or visual cortex

Provides input of written, signed, or spoken word for language processing

Wernicke's area

Converts sound into language

Angular gyrus

Converts words into language


-dyslexia

Arcuate fasiculus

Links Broca's and Wernicke's


Is involved with repetition

Broca's area

Organization of speech production


-Connects to ~motor~



Supramarginal gyrus

Writing integration



Primary motor

Activates areas for speech, voice, or signs

Corpus callosum

Interhermispheric communication, connects left and right language structures

Subcortical areas (thalamus, striatum, etc.)

Regulated, gated feedback loop

Language on the left

Analytical for speech sounds


Grammatical processing


LOCAL


Decoding patterns and systems

Language on the right

GLOBAL

Grand integrater


Prosody


Integration of different stimulus types


Arousal/alertness/attention

Language deficits if damage on left hemisphere

Anomia


Aphasia


Dyslexia/dysgraphia


Spoken/signed/written word deficit

Language deficits if damage on right hemisphere

Lack of initiation


Can't decode speaker's emotional state


Can't integrate face, voice, body, & words

Clues to language processing

-Priming


-Category specific language subdivisions


-Meaningful context

Priming

Semantic


Phonetic


Functional deactivation

Category specific language subdivisions

animate vs. inantimate


category specific deficits in aphasia


imageable words


dual coding theory

meaningful context

sounds vs. words


isolated words vs. sentences

Aphasia

Acquired cmmxn disorder


Comprehension, expression, or botoh affected


often reading and writing disrupted


often due to cerebrovascular accident (CVA)

Broca's aphasia

Lack of fluency


Comprehension fine


Effortful, poorly articulated


content words often preserved, functional words not

Wernicke's

Lack of processing language input (aka problems with comprehension)


Fluency fine


Can't monitor language output

Factors affecting aphasia outcomes

Severity of lesion


Cause of lesion


Location of lesion


Cerebral blood flow


Intensity of Speech Language Therapy

Treatment Options for CVA

Surgery, Cerebral Angioplasty, tPA

High intensity early intervention

Highly effective


After CVA, neural connections would be messed up due to the condition, rewire brain's framework (neuroplasticity) for neurons to allow connections again