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171 Cards in this Set

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Pediatric Basal Ganglia Calcification

Fahr's Syndrome
Hypo/Hyperparathyroidism
MELAS (Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke)
HIV
Congenital CNS Infections

toxo
rubella
cmv
hiv

Non-Communicating/Obstructive Hydrocephalus

Congenital:
Aqueduct Stenois
Colloid Cyst

Acquired:
Tumors
Hemmorrhage
Venticulitis

Communicating Hydrocephalus

Post-hemorrhage (esp. SAH)
Bacterial Meningitis
Malignant Meningitis
Increased venous obstruction (vein of galen AVM)

Pneumocephalus
Trauma
Post-operative
Osteoma of paranasal sinus
Erosive skull base tumors
Empty Sella: communication with sphemoid sinus
Hyperdense Cerebral Mass
Meningioma
Medulloblastoma
Metastases
Lymphoma
Pituitary Adenoma
Craniopharyngioma
Hematoma
Ependymoma
Giant aneurysm
Colloid Cyst
Isodense Cerebral Mass
Vestibular Schwannoma
Pituitary Adenoma
Hematoma (2 to 3 wks old)
Colloid CYst
Tuberculoma
Hypodense Cerebral Tumor
Glioma
Cystic Craniopharyngioma
Mets
Fat containing tumor: Lipoma/Epidermoid
Hematoma
Abscess
Arachnoid Cyst
Porencephalic Cyst
Hydatid Cyst
Solitary Intracerebral Mass
Primary Brain Tumor
Met
Arterial Infarct
Venous Infarct
Abscess
Acute Demyelinating Plaque
Hematoma
Encephalitis
Aneurysm
Normal Variant Intracranial Calcifications
Pineal
Choroid Plexus
Dura
Basal Ganglia
Habenular Commisure
Dentate Nuclei of Cerebellum
Parasellar Ligaments
Arachnoid Granulations
Vascular Intracranial Calcifications
Vertebrobasilar/Carotis Vessels
AVM
Cavernoma
Abeurysm
Chronic Subdural
Old Infarct
Hematoma
Tumors Causing Intracranial Calcification
Meningioma
Ologodendroglioma
Low grade Glioma
Craniopharyngioma
Mets
Pineal Tumors
Chordoma
Chondrosarcoma
Fatty Midline Tumors (dermoid/lipoma of corpus callosum)
Choroid Plexus Papilloma
Dysembryplastic Neuroepithelial Tumor (DNET)
Central Neurocytoma
Infections Causing Intracranial Calcifications
Torch
Cystercercosis
TB
Neurocutaneous Disorders Causing Intracranial Calcifications
Sturge-Weber
Tuberous Sclerosis
Neurofibromatosis
Basal Ganglia Calcification
Normal Variant
Endocrine: hypo/hyperthyroid
Metabolic:: Mitochondrial Diseases; Leigh's, Fahr's, Cockaynes Syndrome
Toxin: CO, Pb. Anoxia
Post-therapy: chemo
Normal Meningeal Enhancement on CT or MRI
Dural
Leptomeninges
Vessels
Dural Enhancenment on CT or MRI
Infection
Tumor
Post-operative
S/P LP
Intracranial Hypotension
Venous Thrombosis
Idiopathic Pachymeningitis
Extramedullary Hematopoiesis
Sarcoid
Rheumatoid Arthritis
Leptomeningeal Enhancement on CT or MRI
Infection
Tumor
Infarct
SAH (sub-acute)
Sarcoid
RA
Sturge Weber
Enhancement of Ependyma on CT/MRI
Infective Ventriculitis
Tumor: breast, lung, leukemia, lymphoma
Post-intracentricular Hemorrhage
Enarged Ependymal Veins
Iatrogenic
Enhancement Subarachnoid Space on CT/MRI
Meningitis
Tumor
Post-Angiogram
Multiple Ring Enhancing Lesions
Mets
Abscess
Demyelination
Multifocal Glioma
Lymphoma
Contusion/Hematoma
pulsatile tinnitus
glomus jugulare
glomus tympanicum
high jugular bulb
aberrant carotid artery
dural avm
cavernous carotid fistula
menigioma
gliomatosis
gliomatosis cerebri
lymphomatosis crebri
multicentric glioma
viral encephalitis
vasculitis
adem
supratentorial ependymoma
pnet
malignant rhabdoid tumor
gbm
anaplastic astrocytoma
mets
adult lateral ventricular mass atria
meningioma
met
choroid plexus xanthogranuloma
child lateral ventricular mass atria
choroid plexus papilloma
choroid plexus papilloma
ependymoma
adult lateral ventricular mass body
subependymoma
oligodendroglioma
central neurocytoma
astrocytoma
child lateral ventricular mass body
astrocytoma
pnet
teratoma
choroid plexus papilloma
child lateral ventricular mass foramen of monroe
giant cell astrocytoma
adult lateral ventricular mass foramen of monro
giant cell astrocytoma
central pontine myelinolysis
ms
adem
ischemia/infarction
infiltrating neoplasm
noncommunicating hydrocephalus
foramen of monro obstruction
3rd ventricle tumors
colloid cyst
oligodendroglioma
central neurocytoma
giant cell astrocytoma(ts)
ependymoma
meningioma

aqueduct obstruction
congenital stenosis
ventriculitis
intraventricular hemorrhage

tumors
mesencephalic
pineal, posterior 3rd vent region
tectal glioma

4th ventr obstruction
dandy walker malformation
ivh
infection (cysticercosis)
subependymoma
exophytic brainstem glioma

posterior fossa tumors
ependymoma
medulloblastoma
hemangioblastoma
metastasis
astrocytoma
communicating hydrocephalus
meningititis
infectious
carcinomatosis
sah
trauma
surgery venous thrombosis
extra-axial mass
meningioma
mets
lymphoma
arachnoid cyst
dermoid/epidermoid
hemorrhage
infection
extra-axial mass in the region of the clivus or pre-pontine cistern
mets
meningioma
chordoma
chondroma
chondrosarcoma
extra-axial cpa mass
cn 8 mc (5 and 7) neuroma
meningioma
epidermoid
paraganglioma
petrous apex cholesterol cyst
aneurysm
mets
arachnoid cyst
dermoid
intra-axial hemispheric mass
astrocytoma
oligodendroglioma
glioblastoma
lymphoma
mets
pnet
ganglioma/cytoma
intraxial sella mass
adenoma
craniopharyngioma
rathke's cyst
mets
abscess
sarcoid
eg
intraxial pineal mass
germ cell tumor
pineal parenchymal tumor
intraxial cerebellum tumor
astrocytoma
medulloblastoma
hemangioblastoma
mets
ependymoma
choroid plexus papilloma
choroid plexus carcinoma
multiple lesions
Tumor
Metastases
Multicentric glioma
Lymphoma

infection
Abscess
Fungus
Cysticercosis
Toxoplasmosis

Vascular
Embolic
infarctions
Multifocal hemorrhage
Diffuse axnal injury
Contusions
Cavernous hemangiomas
Vasculitis
Corpus Callosum Lesions
Tumors
Astrocytoma butterfly glioma
Lymphoma
Lipoma (midline)

Demyelinating disease
Multiple sclerosis
Marchiafava-Bignami disease (alcoholics)
Progressive multifocal leukoencephalopathy (rarely enhances)
Infarct (always also involves cingulate gyrus
Intrasellar Masses
Pituitary adenoma
pituitary apoplexy
craniopharyngioma
rathke's cleft cyst
pars intermedia cyst
aneurysm
abscess
SUPRASELLAR Masses
SATCHMOE
Sarcoid
Aneurysm/arachnoid cyst
Teratoma/germinoma/epidermoid
Craniopharyngioma
Hamartoma of the tuber cinereum
Meningioma/mets
Optic glioma
EG
SELLAR MASSES
PC OR MAC?

Pituitary adenoma/apoplexy
Craniopharyngioma
Mets/meningioma
Abscess/Aneurysm
Cysts—Rathke’s cleft
PARASELLAR MASS
MCAT

Meningioma/metastasis
Cavernous carotid fistula
Aneurysm
Trigeminal Schwannoma/Tolosa-Hunt
Adult Supra or parasellar mass
adenoma
meningioma
aneurysm
glioma
Child Supra or parasellar mass
Craniopharyngioma
Glioma
Adult Suprasellar Masses
Macroadenoma (most common)
Meningioma
Glioma
Craniopharyngioma
Aneurysm (rare, but important)
Child Suprasellar Masses
Craniopharyngioma (most common)
Glioma (optic nerve, chiasm, hypothalamus)
Germinoma
Hypothalamic hamartoma
E G
POSTERIOR FOSSA
lateral posterior fossa tumor
astrocytoma
anterior posterior fossa tumor
brainstem glioma
posterior/midline posterior fossa tumor
medulloblastoma
4th ventricle posterior fossa tumor
ependymoma
tumor spread through foramina of luschka and magendi
ependymoma
cystic posterior fossa tumors
pilocytic astrocytoma
hamangioblastoma
dense cell packing posterior fossa tumors
medulloblastoma
Adults Posterior Fossa Tumors
Metastases
Hemangioblastoma
Astrocytoma
Extraaxial tumors (meningioma, schwannoma, epidermoid
Children Posterior Fossa Tumors
Cerebellar astrocytoma
Medulloblastoma
Brainstem glioma
Ependymoma
BRAIN TUMORS IN INFANTS (< 2 YEARS)
Teratoma (most common)
PNET (primary cerebral neuroblastoma)
Choroid plexus papilloma/carcinoma
Anaplastic astrocytoma
Adult Intraventricular tumors
Gliomas
Astrocytoma (including giant cell type)
Subependymoma
Meningioma
Metastases
Cysticercosis
Children Intraventricular tumors
Choroid plexus papilloma
Ependymoma
PNET (medulloblastoma)
Teratoma
Astrocytoma
I 5-30 yeors intraventricular tumors
Glioma
Juwenile pilocytic astrocytoma
0-15 yrs lateral ventricular masses
pnet
choroid plexus papilloma
15-30 years laterl ventricular tumor
glioma
jpa
>30 yrs lateral ventricular tumor
subependymoma
astrocytoma
mets
oligodendroglioma
meningioma
central neurocytoma
0-15 yrs 3rd ventricle masses
astrocytoma
EG of stalk
germinoma
extrinsic craniopharyngioma
15-30 yrs 3rd ventricle masses
colloid cyst
>30 yrs 3rd ventricle masses
glioma
mets
pituitary mass
pineal mass
aneurysm
sarcoid
0-15 yrs 4th ventricle masses
ependymoma
medulloblastoma
15-30 yrs 4th ventricle masses
choroid plexus papilloma
>30 yrs 4th ventricle masses
hemangioblastoma
mets
subepenymoma
CEREBELLOPONTINE ANGLE (CPA) MASS
Acoustic neuroma 90%
Meningioma,
Epidermoid
Arachnoid cyst
Metastases
Vertebrobasilar dolichoectasia
Exophytic glioma
Ependymoma through Luschka
Brainstem astrocytoma
Lipoma
CYSTIC MASSES
Neoplastic

Cystic astrocytoma /GBM
Hemangioblastoma
Metastases: sq cell carcinoma

Benign

(usually no peripheral enhancement)
Dermoid/epidermoid
Arachnoid cyst
Colloid cyst
Cavum variants
Cavum septum pellucidum
Cavum vergae
Cavum velum interpositum
TUMORS WITH CSF SEEDING
Choroid plexus papilloma/carcinoma
Ependymoma
PNET tumors
Medulloblastoma
Pinealblastoma
Cerebral neuroblastoma
Germinomas
GBM
HYPERDENSE LESION (CT)
Tumors
High-cell density
Lymphoma
PNETs (medulloblastoma)
Ependymoma
Germinoma
Other PNET

Hemorrhagic Tumors
GBM
Metastases: kidney, lung, melanoma, choriocarcinoma (mnemonic: CT/MR:
choriocarcinoma, thyroid, melanoma, renal cell carcinoma)

Calcified tumors (rare)
Mucinous metastases
All osteogenic tumors
T2 HYPOINTENSE LESIONS (MRI)
Paramagnetic effects
Ferritin, hemosiderin
Deoxyhemoglobin
ntracellular methemoglobin
Melanin

Low spin density
Calcification
High nucleus/cytoplasm ratio (lymphoma, myeloma, neuroblastoma)
Fibrous tissue (meningioma)

Other
High protein concentration, > 35%
Flow signal void
T1 HYPERINTENSE LESIONS (MRI)
Paramagnetic effects
MRI contrast agent: Gd-DTPA
Methemoglobin
Melanin
Ions: manganese fe copper, certain states of calcium

Other
Fat dermoid
Very high protein concentration (i.e., colloid cyst)
Slow flow
LESIONS WITH NO ENHANCEMENT
Cysts
Tumors with intact blood-brain barrier (low-grade gliomas)
LESIONS WITH STRONG ENHANCEMENT
Meningioma
PNET (e.g., medulloblastoma)
AVM
Paraganglioma (very vascular)
Aneurysm (nonthrombosed)
HIV-associated lymphoma
Glioblastoma multiforme
Temporal Lobe T2W Hyperintense Lesions
HSV Encephalitis
Limbic Encephalitis(paraneoplastic)
Venous Infarct
Trauma
Lymphoma
Tumors (low grade glioma, ganglioglioma)
Multiple Suseptibility Hypointense lesion on MRI
Amyloid Angiopathy
Cavernomas
DAI
RING ENHANCEMENT
Tumor
Primary brain fumors
Metastases
Lymphoma (AIDS)

Infection, inflammation
Abscess
Granuloma
Multiple sclerosis
Toxoplasmosis
Cysticercosis

Vascular
Resolving hematoma
Infarct (nonacute)
Thrombosed vascular malformationThrombosed aneurysm
Vasculitis
DIFFUSE MENINGEAL ENHANCEMENT
Meningitis (viral, bacterial)
Carcinomatosis
Lymphoma
Metastases
Postoperative/postshunt
SAH
ntracranialhypotension
CSF leak
BASILAR MENINGEAL ENHANCEMENT
Infection
TB (most common)
Fungal
Pyogenic (more common on convexity)
Cysticercosis

Tumor
Lymphoma, leukemia
Carcinomatosis

lnflammatory
Sarcoid
Rheumatoid pachymeningitis
Whipple's disease
EPENDYMAL ENHANCEMENT
Tumor
Lymphoma
Metastases (lung, melanoma, breast)
CSF seeding
PNET
GBM

Infection
Spread of meningitis
CMV (rare)
Inflammatory ventriculitis
Postshunt/instrumentation
Posthemorrhage
T2 HYPOINTENSE BASAL GANGLIA LESIONS
Old age
Any chronic degenerative disease
MS
Parkinsonian syndromes
Childhood hypoxia
T2 HYPERINTENSE BASAL GANGLIA LESIONS
Mnemonic: "TINT"

Tumor
Lymphoma

Ischemia
Hypoxic encephalopathy
Venous infarction (intemal cerebral vein thrombosis)

Neurodegenerative diseases (uncommon)
Huntington's disease
Wilson's disease
Hallervorden-Spatz disease
Mitochondrial encephalopathies (e.g.,
Aminoacidopathies

Toxin
CO, CN F{2S poisoning
Hypoglycemia
Methanol
Leigh /Keams-Sayer syndrome)
T1 HYPERINTENSE BASAL GANGLIA LESIONS
Dystrophic calcifications (any cause)
Hepatic failure
Neurofibromatosis 1
Manganese (used in formulas for TPN)
BASAL GANGLIA CALCIFICATION (INCREASED CT DENSITY)
Senescent/physiologica/li diopathic calcification (most common)
Metabolic calcification
Hypoparathyroidism (most common metabolic cause)
Pseudohypoparathyroidism
Pseudopseudohypoparathyroidism
Hyperparathyroidism

Infection
TORCH, AIDS
Postinflammatory: TB, toxoplasmosis
Cystercosis (common)

Toxic/postanoxic
Lead
C O
Radiation therapy
Chemotherapy
Other
Fahr's disease
Mitochondrial (common), encephalopathies (uncommon)
Cockayne's svndrome
SPECTRUM OF CYSTIC SUPRAIENTORIAL
CONGENITAL ABNORMALITIES
Holoprosencephaly
Hydranencephaly
Aqueductal stenosis (severe obstruction
hydrocephalus)
Callosal dysgenesis (interhemispheric ryst)
o Other
Porencephaly
Arachnoid cyst
Cystic teratoma
Epidermoid/dermoid
Vein of Galen AVM
POSTERIOR FOSSA CYSTIC ABNORMALITIES
DW malformation (vermian hypoplasia/aplasia and large posterior fossa)
DW variant (normal size posterior fossa and vermian hypoplasia
Mega cisterna magna (normal vermis)
Retrocerebellar arachnoid cyst (must show mass effect)
Chiari IV (near complete abscence of cerebellum)
o Other
Epidermoid/dermoid
Cystic tumor
diffuse replacement of fatty marrow with hypointense tissue
hem malignancy
lymphoma
leukemia
myeloma

granulomatous disease
sarcoid
tb

anemia
thalassemia
blood loss
aids
mets
Spoils System
Franchise extended - more people were given the right to vote, even men who owned no land. Spoils system - "To the victor go the spoils" - the winner of the election may do whatever they want with the governmental workers. Jackson made more staff changes than any previous president, firing many people and replacing them with his own supporters.
infindibular lesion in adults
sarcoid
tb
mets
lymphocytic hypophysitis
ddx ganglioglioma
low grade astrocytoma
jpa
dnet (dysembryoplastic neuroepithelial tumor)
pxa (pleomporphic xanthoastrocytoma)
non-neoplastic cystic mass in the posterior fossa
dandy walker
cisterna magna
arachnoid cyst
4th ventr neoplasm
ependymoma (mc peds)
meningioma
choroid plexus tumor
papilloma
hemangioma
intradiploic epidermoid cyst
hemangioma
eg
leptomeningeal cyst
diffuse dural enhancement
intracranial hypotension
mets (breast/prostate)
lymphoma/leukemia
granulomatous dz(tb, sarcoid, wegners, erheim-chester, lipid granulomatosis)
idiopathic hypertrophic pachymeningitis
ddx leptomeningeal enhancement
carcinomatous meningitis
csf subarachnoid seeding from cns malignancy
granulomatous dz(sarcoid/tb)
infectious meningitis
ddx pediatric brainstem mass
astrocytoma
demyelinating dz(adem)
rhomboencephalitis
tb
lymphoma
ddx benign appearing petrous apex mass
cholesterol granuloma
mucocele
epidermoid cyst
ddx agressive cystic appearing petrous apex masses
hemorrhagic mets
plasmacytoma
melanoma
intracranial hypointense T2 lesions
meningioma
lymphoma
plasmacytoma
mets
sarcoid
ddx press
iv drugs - cocaine
chemo agents
radiation
pre-eclampsia
ddx peds midline posterior fossa mass
medulloblastoma
ependymoma
cereballar astrocytoma
DDX bright csf on FLAIR
SAH
Meningitis
Meningeal Carcinomatosis
SSS Thrombosis
Status Epilepticus
Renal Failure
Hyperoxygenation
Previous Gadolinium Study
DDX cortically based mass with leptomeningeal involvement
inflammatory
granulomatous disease
lymphoma
mets
primary brain tumors
DDX high signal intensity at the apex or emminence of the stalk
ectopic post pituitary
tuber cinereum lipoma
fat in the dorsum sellae
ddx ectopic post pituitary
lch
hemosiderosis
failure of development
injury
DDX opthalmoplegia
mitochondrial defects: SANDO, Kearns-Sayre
ms
oculopharyngeal dystrophy
DDX cystic mass with enhancing nodule
pilocytic astrocytoma
hemangioblastoma
mets
DDX dense sclerotic vertebrae
osteoblastic mets
pagets
lymphoma
myelosclerosis
fracture
clumping of nerve roots with smooth and nodular enhancement of the cauda equina c/w leptomeningeal disease
sarcoid
drop mets(gbm,ependymoma,medulloblastoma)
lymphoma
melanoma
carcinomatous meningitis
ddx dumbell shaped tumors
nerve sheath (schwannoma, neurofibroma)
meningioma
ganglioneuroma
neurobalstoma
DDX Psoas Mass
Retroperitoneal sarcoma
lymphoma
metastatic diseas
granulomatous disease
fungal infection
DDX odontoid and periodontoid region
primary bone tumor
chordoma
met
plasmacytoma
lymphoma
meningioma
DDX smooth leptomeningeal enhancement
infection
sarcoid
carcinomatous meningitis
lymophoma
guillain-barre
CIDP(chronic inflammatory demyelinating polyradiculoneuropathy)
HMSN (hereditary motor and sensory neuropathies.
DDX diffuse enlargement of peripheral nerves
NF1
Dejerine-Sottas Disease
Charcot Marie Tooth Disease
DDX Enhancing lesions in pedicles
osteiod osteoma
mets
ascending lumbar veins
DDX enhancing optic nerve
devic syndrome
sle
sarcoid
adem
ddx spine neuropathic arthropathy
mets
osteomyelitis
dm
neurosyphilis
congenital pain absence
syringomyelia
charcot-marie tooth
ddx osteosclerotic mets
prostate
breast
ovarian
tcc
carcinoid
lymphoma
ddx extramedullary intradural spinal tumors
schwannoma
meningioma
lipoma
Vertebra Plana
LCH
MM
Mets
Ewings
Lymphoma
Gaucher's
ABC
Trauma
Infection
single vertebral level ossification of the ligamentum flavum
calcified ligamentum flavum hematoma
calcified meningioma
calcified epidural hemangioma
ddx epidural fat
epidural lipomatosis
lipoma
angiolipoma
DDX ABC
UBC
Chondroblastoma
GCT
Telangiectatic Osteosarcoma
vertebral biconcavity
scd
thalassemia
gauchers
spherocytosis
homocystinuria
high signal in central cord
ms
adem
vasculitis
infarction
Bright T1 intramedullary mass
lipoma
dermois/epidermoid
subacute thrombus
non-neoplastic conditions that mimmick infection in the spine
renal spondyloarthropathy a/w hemodialysis
neuropathic spondyloarthropathy a/w tabes dorsales
dm
trauma
severe djd
DDX Normal sized globe with an intra-ocular soft tissue mass showing calcification
retinoblastoma,
Coat’s disease
toxocariasis.
differential diagnosis of leukocoria in a child includes
retinoblastoma,
Coat’s disease,
toxocariasis, retinopathy of prematurity,
optic nerve drusen, persistent hyperplastic primary vitreous phthisis bulbi.
With a normal sized globe and intra-ocular calcifications the differential narrows down to retinoblastoma, Coat’s disease and toxocariasis with retinoblastoma being the most common.
tumors spreading via csf
medulloblastoma,
germinoma,
pilomyxoid astrocytoma
ependymoma.
differential diagnosis of a suprasellar mass in an infant or young child would include pilocytic astrocytoma, craniopharyngioma, and pilomyxoid astrocytoma
pilocytic astrocytoma, craniopharyngioma,
pilomyxoid astrocytoma
Differential considerations for a lucent lesion in the calvaria after intracranial radiotherapy include
metastasis,
osteoradionecrosis,
radiation-induced osteosarcoma.
DDX Dural Sinus Thrombosis
Anatomic variant
Dural sinus thrombosis
Fat within dural sinus
Acute hemorrhage
DDX Dural Sinus Thrombosis
Anatomic variant
Dural sinus thrombosis
Fat within dural sinus
Acute hemorrhage
DDX aggressive spinal hemangioma
Ewing's sarcoma,
osteosarcoma,
plasmacytoma,
osseous hemangioblastoma osseous lymphangioma.
DDX Locked in Syndrome
most commonly occur following a basilar artery thrombosis with secondary occlusion of the perforating arteries. Other causes of LIS are hemorrhage, head trauma, tumors, central pontine myelinolysis, demyelinating diseases, or infectious conditions. Severe forms of Guillain-Barre syndrome or amyotrophic lateral sclerosis can present a LIS-like clinical picture without necessarily involving a pontine lesion.
DDX Cavernous Mlaformation
Neurenteric cyst
Epidermoid/dermoid cyst
Arachnoid cyst
Cystic schwannoma
Neurocysticercosis
DDX superficial siderosis
repetitive minor postoperative hemorrhage from hemostatically unstable pia, hemorrhagic neoplasm such as ependymoma, vascular anomalies, intraspinal fluid-filled collections, and repetitive trauma. A definitive etiology is elucidated in as few as 50% of cases.
DDX Metachromatic Leukodystrophy
demyelinating disorders and leukodystrophies affecting toddlers/children, including TORCH (toxoplasmosis, other agents, rubella, cytomegalovirus, herpes simplex) infections and pseudo-TORCH syndromes, periventricular leukomalacia, Pelizaeus-Merzbacher disease, and Krabbe disease
DDX Dural Thickening
The causes of dural thickening include: (1) infiltrative disorders like leukemia, lymphoma, Langerhans cell histiocytosis; (2) granulomatous diseases like tuberculosis, sarcoidosis, Wegener granulomatosis; (3) metastatic diseases like neuroblastoma; (4) post ventriculoperitoneal shunt insertion; (5) postcraniectomy; and (6) patients with spontaneous intracranial hypotension syndrome.
ddx vertical trabeculations of the vertebral body
hemangioma
pagets- thickened cortical bone
mets: bony destruction of end plates
mm: plasma cells on bx
what is your systematic approach to MRI of the spine
1)check fat marrow signal of the vertebral bodies
2)check alignment
3)start from top and work your way down looking for vertebral abnormalities
what is the managemet of disc herniation
1)nsaids and bedrest
2) if step 1 fails then 3 epidural injections of steroids.
3)if 1 and 2 fail surgery
what is a complication of GCT
sarcomatous transformation.

never radiate benign bone lesions
ddx of a mass in the masseter muscle
adult
peds
adult
abscess: h/o tooth extraction
schwannoma b/c v3 runs in the masseter muscle

peds
rhabdomyosarcoma
hemangioma
ddx posterior fossa mass in an adult
mets
hemangioblastoma
lymphoma
ddx mass in the pineal gland
adult
child
adult:
pinealcytoma
mets from lung ca
lesion adjacent to pineal gland (glioma)

peds:
germ cell tumor (germinoma, teratoma)
pinealblastoma
trilateral retinoblastoma
ddx msdd in the jugular foramen
meningioma
paraganglioma (glomus jugulare)
schwannoma
ddx increase T2 intramedullary signal spine
MS: short segment, check brain for lesions
transverse myelitis: long segment
infarct/ischemia
sarcoid: check cxr, elevated ace levels, edema of the cord
ddx axial ct scan showing hyperdensity in the region of the basal ganglia with blood in the ventricles
hypertensive hemorrhage
gbm with hemorrhage
avm bleeding
ruptured mca aneurysm
ddx pediatric brain tumors in children < 2 yoa
teratoma
pnet
choroid plexus papilloma
ddx hyoerdense lesion ncct head
vascular:
hemorrhagic infarct
avm/cavernous transformation

neoplastic:
hyperdenese met ( renal/thyroid)
lymphoma
ddx primary tumors that seed the brain
medulloblastoma
ependymoma
gbm
pnet
ddx petrous apex lesion
cholesterol granuloma
meningioma
aneurysm
met/lymphoma
GRE shows multiple foci of signal loss throughout the brain
chronic htn
multiple cavernous transformations
amylod angiopaty
ddx enlargement of a rectus muscle of the orbit
thyroid dz: usually b/l
orbital pseudotumor: painful
mets: breast ca
lymphoma
sacoid: cxr b/l lymphadenopathy
ddx cystic mass in parotid gland
1)pleomorhic adenoma: mc parotid mass and can be cystic

2)warthins tumor: elderly male. located in the tail of the parotid

3) lymphoepithelial cysts: aids patient

4)sjogrens syndrome: bilateral female dry eyes and dry mouth usually a/w ra
optic neuritis ddx
ms
devics dz
lyme
sarcoid
ddx hyperdense mass in the back of the tongue
lingual thyroid
lymphoma
hemangioma
DDX leptomeningeal enhancement
is nonspecific and may be seen in any condition resulting in meningeal irritation such as
transient postsurgical meningeal enhancement, infectious meningitis,
subdural hematoma,
sarcoidosis with CNS involvement,
as well as patients receiving intrathecal chemotherapy or radiation therapy.
DDX diffusion restriction on MRI
ischemia,
abscess,
empyema,
epidermoid cyst.
Infectious etiology (septic emboli, abscess) should be considered with diffusion-restricting lesions that appear round, cystic, and hyperintense on T2-weighted images.
DDX intramedullary lesions
ependymomas,
astrocytomas,
hemangioblastomas,
metastases

DDX of an enhancing mass within Meckel cave.

Meningioma
schwannoma
Metastasis
Perineural spread of tumor
Tolosa-Hunt syndrome

DDX Transverse Myelitis

The differential diagnosis for transverse myelitis is broad and includes:


autoimmune,


paraneoplastic,


toxic,


vascular,


and infectious causes. Since spinal cord involvement at any level is typically partial, the neurological deficits produced below the level of the lesion may vary.

DDX Mass Pituitary fossa

  • Pituitary hyperplasia
  • Meningioma of the diaphragma sellae
  • Lymphocytic hypophysitis
  • Craniopharyngioma
  • Aneurysm
  • Metastasis