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99 Cards in this Set
- Front
- Back
Conscious/unconscious awareness of external/internal stimuli.
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Sensation
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Conscious awareness & interpretation of a sensation.
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Perception
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What are the 3 main structures involved in sensations?
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Sensory receptors, sensory nerves, primary sensory area (cortex)
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Each unique type of sensation.
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Sensory modality
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What are the 2 classes of sensory modalities?
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General senses, special senses
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___ senses include somatic (touch, temp, pain, proprioception) & visceral senses (conditions w/in internal organs).
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General
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___ senses include smell, taste, vision, hearing, equilibrium.
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Special
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Sensory receptors respond to (one/multiple) type(s) of stimuli.
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One
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What are 4 events that occur within a sensation?
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Stimulation of sensory receptor, transduction of stimulus into a graded potential, generation of nerve impulse when it reaches threshold, integration of sensory input by CNS.
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What are the 3 classes of sensory receptors?
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Free nerve endings, encapsulated nerve endings, separate sensory cells.
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Class of sensory receptor - bare dendrites. Pain, temp, tickle, itch, light touch.
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Free nerve endings
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Class of sensory receptor - dendrites enclosed in connective tissue capsule. Pressure, vibration, deep touch.
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Encapsulated nerve endings
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Class of sensory receptor - specialized cells that respond to stimuli. Vision, taste, hearing, balance.
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Separate cells that synapse w/ 1st order neurons
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Free/encapsulated nerve endings & olfactory receptors produce ___ potentials that produce action potentials. When large enough, it generates nerve impulse in a 1st order neuon.
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Generator potential
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Graded potentials produced by vision, hearing, equilibrium, taste receptors are called ___ potentials. They release neurotransmitter to 1st order neurons to produce postsynaptic potential which may trigger nerve impulse.
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Receptor potential
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Type of receptor that detects pressure/stretch/deformation. Touch, pressure, vibration, hearing, proprioception, equilibrium, BP.
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Mechanoreceptor
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Type of receptor that detects temperature.
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Thermoreceptor
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Type of receptor that detects pain from damage to tissue. Free nerve ending found in almost every body tissue except ___.
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Nociceptor. Brain.
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Type of receptor that detects light.
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Photoreceptor
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Type of receptor that detects chemicals for taste, smell, & body fluid changes.
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Chemoreceptor
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Type of receptor that detects osmotic pressure of body fluids.
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Osmoreceptor
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Type of receptor near body surface & receives external stimuli. Hearing, vision, smell, taste, touch, pressure, pain, vibration, temp.
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Exteroceptor
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Type of receptor found in BV, viscera, mm, etc that monitors internal environment. Not consciously felt except pain, pressure.
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Interoceptor (visceroceptor)
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Type of receptor found in mm, tendon, joint, internal ear. Sense body position, mm length/tension, jt movt.
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Proprioceptor
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Characteristic of sensory receptors where there is decreased sensitivity/responsiveness to prolonged stimuli.
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Adaptation
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(Rapid/slow) adapting receptors are specialized for detecting changes, ie smell, pressure, touch.
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Rapidly adapting
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(Rapid/slow) adapting receptors continue to send impulses as long as stimulus persists, ie pain, body position, blood composition.
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Slowly adapting
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Somatic sensations that arise from skin surface are called ___ sensations. Modalities: tactile, thermal, pain, proprioceptive.
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Cutaneous
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___ sensations are touch, pressure, vibration, itch, tickle.
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Tactile
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Rapidly adapting receptor for discriminative touch, vibration. Dendrites enclosed in dermal papillae of hairless skin.
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Meissner's corpuscle (corpuscle of touch)
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Type of rapidly adapting receptor w/ free nerve endings found around hair follicles that detect hair movt.
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Hair root plexus
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Type of slow adapting receptor w/ flattened dendrites touching merkel cells of stratum basale. Discriminative touch.
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Merkel disc
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Encapsulated slow adapting receptor found deep in dermis, ligs, tendons, hands, soles. Most sensitive to stretching. Heavy/continuous touch, pressure.
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Ruffini corpuscle
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Sustained sensation felt over a larger area than touch & occurs w/ deformation of deeper tissues.
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Pressure
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Onion-like CT capsule enclosing a dendrite. Rapidly adapting & found in dermis/subQ layer & widely distributed (viscera, jts, mm, etc). Senses pressure/high-frequency vibration. Respond to acceleration/deceleration of jts.
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Pacinian corpuscle
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Itch sensation is caused by stimulation of free nerve endings by certain ___, ie bradykinin often b/c of local inflammatory response.
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Chemicals
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Condition where pts w/ amputated limb still experience sensations as if limb were still there. May be caused by sensory nerves or part of brain that used to carry/integrate info for amputated limb.
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Phantom limb sensation
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Cold receptor is found in ___ layer & respond to temps b/w 50-105º F.
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Stratum basale
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Warm receptors found in ___ respond to temps b/w 90-118º F.
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Dermis
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Pain is produced below ___º & over ___º F.
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50-118º F
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What can activate nociceptors?
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Thermal, mechanical, chemical stimuli. Excessive distension, mm spasm, inadequate blood flow.
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Tissue injury releases what chemicals?
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K+, kinins, prostaglandins
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Type of pain that occurs rapidly after stimuli (0.1 sec). Sharp pain like needle puncture/cut. Not felt in deeper tissues.
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Fast pain (acute)
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Type of pain that begins more slowly & increases in intensity. Aching, throbbing, burning. Found in both superficial & deeper tissues.
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Slow pain (chronic)
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Pain that can be superficial if arising from skin or deep if from skeletal mm, jts, tendons.
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Somatic pain
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Pain felt in/under skin overlying stimulated organ. Localized damage may not be painful but diffuse visceral manipulation severe.
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Visceral pain
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Phenomena where pain is felt in surface area far from stimulated organ.
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Referred pain
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Where is referred pain for heart attack felt & what spinal cord segment?
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Skin along left arm & segment T1-T5
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2 drugs that block formation of prostaglandins that stimulate nociceptors.
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Aspirin, ibuprofen
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Anesthetic that blocks conduction of nerve impulses along pain fibers.
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Novocaine
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Narcotic-opiate that lessens the perception of pain in brain.
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Morphine
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Ability to assess weight of an object.
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Weight discrimination
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Sensory info for proprioception is sent to where?
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Cerebellum, cerebral cortex
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What are 3 types of proprioceptors?
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Mm spindles, tendon organs, jt kinesthetic receptors
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Muscle spindles are (slow/fast) adapting.
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Slow
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Specialized mm fiber that is wrapped w/ mm spindle.
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Intrafusal mm fiber
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What are the only mm that lack mm spindles?
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Mm of middle ear
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Which mm have more mm spindles?
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Those that control fine movt
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What do mm spindles detect? How do they react?
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Mm length/stretch. Contract to prevent overstretching.
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Neurons found at both ends of intrafusal fibers & adjust tension in mm spindle to variations in mm length.
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Gamma motor neurons
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Ordinary skeletal mm fibers are called ___ fibers supplied by ___ neurons.
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Extrafusal. Alpha motor.
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Where are golgi tendon organs found?
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Junction of tendon & mm
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What do golgi tendon organs detect? How do they react?
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Tension/contraction. Relaxes mm to prevent excessive tension.
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What 2 receptors are found in jts?
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Ruffini & pacinian corpuscles
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Where do somatic sensory pathways relay info in the brain? At the same time, axon collaterals of these neurons send signals where?
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Primary somatosensory area in cerebral cortex. Cerebellum, reticular formation of brain stem.
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Somatic sensory neuron that conducts impulses from somatic receptors to brain/spinal cord, ie cranial/spinal nn.
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1st order neuron
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Somatic sensory neuron that conducts impulses from brain stem/spinal cord to thalamus. Decussates to opposite side of brain.
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2nd order neuron
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Somatic sensory neuron that conducts impulses from thalamus to primary somatosensory cortex (postcentral gyrus of parietal lobe).
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3rd order neuron
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Regions in CNS where neurons synapse & are part of sensory/motor pathway called ___.
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Relay stations
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Pathway to cortex for conscious proprioception & tactile sensations. Neurons part of posterior columns - consist of gracile/cuneate fasciculus. Fine touch, stereognosis, proprioception, vibratory sensations.
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Posterior column-medial lemniscus pathway
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In posterior column-medial lemniscus pathway, signals travel up spinal cord in ___. Cross over in ___ to become ___ ending in ___. These fibers reach ___.
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In posterior column-medial lemniscus pathway, signals travel up spinal cord in POSTERIOR COLUMN. Cross over in MEDULLA to become MEDIAL LEMNISCUS PATHWAY ending in THALAMUS. These fibers reach CORTEX.
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Pathway that carries pain, temp, tickle, itch, crude touch, pressure.
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Anterolateral or spinothalamic pathway
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What 2 tracts are involved in spinothalamic pathway?
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Lateral spinothalamic (pain temp), anterior tract (tickle, itch, crude touch, pressure).
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In spinothalamic pathway, 1st order neurons connect ___ w/ synapses in ___. 2nd order sensory neurons in ___ matter of spinal cord send fibers to other side of spinal cord & up ___ matter to synapse w/ ___. 3rd order in thalamus projects to ___.
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In spinothalamic pathway, 1st order neurons connect RECEPTOR CELLS w/ synapses in SPINAL CORD. 2nd order sensory neurons in GRAY matter of spinal cord send fibers to other side of spinal cord & up WHITE matter to synapse in THALAMUS. 3rd order in thalamus projects to CEREBRAL CORTEX-PRIMARY SENSORY AREA.
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Relative sizes of cortical areas are proportional to what 2 things? How can they be modified?
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# of sensory receptors, sensitivity of each body part. Modified w/ learning.
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Where is the primary somatosensory area?
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Postcentral gyrus of parietal lobe
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What 2 tracts are the major routes for proprioceptive impulses reaching the cerebellum?
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Anterior & posterior spinocerebellar tracts
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Impulses to cerebellum detect what?
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Posture, balance, coordination of skilled movts
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Condition that causes progressive degeneration of posterior spinal cord. Caused by bacterium treponema pallidum. Loss of somatic sensations. Proprioceptive impulses fail to reach cerebellum. Gait uncoordinated/jerky.
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Syphilis
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Upper motor neurons extend from ___ to ___ or ___. Lower motor neurons extend from ___ or ___ to ___ (also called ___ b/c many regulatory mechanisms converge here).
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Cortex, brain stem, spinal cord. Brain stem, spinal cord, cortex. Final common pathway.
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What is the primary function of the cerebellum?
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Corrects/refines voluntary mm contraction & posture based on sensory info from body about actual movts. Senses equilibrium (posture/balance).
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What is the fn of basal ganglia?
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Establish mm tone, starts/stops, corrects movt (semivoluntary automatic), inhibits unwanted movt, influences cortical fn including sensory, limbic, cognitive, linguistic fns.
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Condition of damage to lower motor neurons. No voluntary movt on same side of damage, no reflex actions, mm limp/flaccid, decreased mm tone.
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Flaccid paralysis
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Condition of damage to upper motor neurons. Paralysis on opposite side from injury, increased mm tone, exaggerated reflexes.
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Spastic paralysis
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How is input to lower motor neurons different in a direct vs indirect pathway?
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Direct - input directly from cortex. Indirect - input from motor centers in brain stem.
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What 3 cortex areas contribute to descending motor pathways? Where are they located?
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Primary motor area - precentral gyrus, frontal lobe. Premotor area - frontal lobe. Somatosensory area - postcentral gyrus, parietal lobe. (p519 AP)
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Corticle area devoted to mm is proportial to the # of ___.
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Motor units
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Direct motor pathways consist of what 3 pathways?
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Anterior/lateral corticospinal, corticobulbar pathway
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Most upper motor neurons decussate in ___.
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Medulla
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Lateral corticospinal tract - upper motor neurons originate from ___ & travel through ___, then 90% decussate in ___. Form ___ column & synapse in ___ gray horn of spinal cord.
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Upper motor neurons originate from CORTEX & travel through CEREBRAL PEDUNCLES, then 90% decussate in MEDULLA. Form LATERAL WHITE column & synapse in ANTERIOR gray horn of spinal cord.
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Anterior corticospinal tract - upper motor neurons originate from ___ & travel through ___, then 10% continue in ___ column & synapse in ___ gray horn of spinal cord.
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Upper motor neurons originate from CORTEX & travel through CEREBRAL PEDUNCLES, then 10% continue in ANTERIOR WHITE column & synapse in ANTERIOR gray horn of spinal cord.
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What is the fn of the lateral vs anterior corticospinal tract?
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Lateral - skilled movts distal limbs (hands, feet). Anterior - neck/trunk mm.
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Corticobulbar tract - upper motor neurons originate from ___ & travel through ___, then end at motor nuclei of cranial nn except which 3?
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Corticobulbar tract - upper motor neurons originate from CORTEX & travel through CEREBRAL PEDUNCLES, then end at motor nuclei of all cranial nn except OLFACTORY, OPTIC, VESTIBULOCOCHLEAR.
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What is the fn of the corticobulbar tract?
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Head mm movt - eyes, tongue, chewing, expression, speech, neck.
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Amyotrophic lateral sclerosis causes progressive mm weakness. No cure, several cause theories, drugs treat symptoms. Death 2-5 years. It attacks what 3 areas of the CNS?
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Motor areas of cortex, axons upper motor neurons, cell bodies lower motor neurons.
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What are the 5 tracts that form the indirect motor pathways (extrapyramidal)? Where do they receive input? What is each fn?
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Rubrospinal - red nucleus of midbrain (hand movt), tectospinal - sup colliculi of midbrain (body movt reflex to auditory/visual stimuli), vestibulospinal - vestibular nucleus of medulla (balance/posture), medial/lateral reticulospinal tracts - reticular formation (mm tone, posture).
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What is the circuit of the basal ganglia w/ cortex & thalamus?
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Cortex, basal ganglia, thalamus, cortex
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What results from damage to basal ganglia?
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Uncontrollable, abnormal body movt, mm rigidity, tremors, cognition, behavior.
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What is the primary function of the cerebellum?
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Corrects/refines voluntary mm contraction & posture based on sensory info from body about actual movts. Senses equilibrium (posture/balance). Active in learning & rapid, highly skilled movts.
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