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22 Cards in this Set

  • Front
  • Back
What are the three types of neurons?
1-Sensory (afferent)
2-Motor (efferent)
3-Interneurons
What are 3 major functions of sensory neurons?
1-Conduct nerve impulses from a sensory receptor
2-Deliver sensory info to brain & spinal cord
3-Travel from periphery to more central structures

* ~ 5 million
What are the major functions of motor neurons?
1-Carry neural instructions from brain to muscles or glands
2-Travel from CNS to periphery

* A few hundred thousand
What is the function of interneurons?
Make up the neural tissues of brain & spinal cord

*most numerous: billions
What are the 3 types of neurons making up the efferent nervous system?
1-Upper Motor Neuron (UMN); do not directly stimulate target muscle
2-Lower Motor Neuron (LMN); bring nerve impulse to muscles
3-Interneuron - synapse between UMN & LMN
Name the 4 functional subdivisions of the Motor System
1-Direct activation pathway (UMN)
2-Indirect activation pathway (UMN)
3-Control circuits (UMN)
4-Final common pathway
Name the subdivisions of the direct activation pathway
Direction activation pathway:
1-Corticobulbar tracts (cortex to brain stem)
2-Corticospinal (cortex to spinal)
Name the subdivisions of the Indirect activation pathway
1-Corticorubral
2-Corticoreticular
3-Rubrospinal
4-Vestibulospinal
What are the control circuits of the UMN pathway?
1-Basal ganglia
2-Cerebellum
Name the two types of nerves of the final common pathway (LMN)
1-Cranial
2-Spinal
What is a motor unit?
A LMN and the muscle fibers innervated by it.

* Each axon in a nerve may innervate several muscle fibers
* Each muscle fiber may receive input from branches of several different alpha motor neurons
What are the 2 ways by which muscle contraction can be gradiated?
1-temporal summation: increase rate of firing
2-spatial summation: recruit a greater number of motor units
What is the innervation ratio?
The number of muscle fibers per axon

* greater number of muscle fibers per axon = stronger, but cruder movements
* fine discrete movements have smaller innervation ratios
What are the two types of motor neurons?
1-Alpha motor neurons
2-Gamma motor neurons
What is the function of alpha motor neurons?
1-Innervate skeletal muscle
2-innervate interneurons (Renshaw cells)
What is the function of gamma motor neurons?
1-Indirect activation pathway of CNS
2-Involuntary reflexes, limited to specific muscles
3-Maintenance of muscle tone
* influenced by cerebellum & basal ganglia
What is the result of damage to a alpha motor neuron:
1-single alpha motor neuron
2-all alpha motor neurons supplying a muscle
1-weakness or paresis
2-paralysis
What is the result of damage to gamma motor neurons
Muscle tone is too tight or too loose
What is the result of loss of innervation of muscle fibers?
1-Atrophy
2-Fasciculations (spontaneous motor unit discharges)
3-Fibrillation (slow repetitive action potentials, regular contraction - not able to be seen)
What is the result of damage to any of the FCP's for muscles of speech?

*FCP: Final Common Pathway
Flaccid dysartria
What types of nerves make up the FCP for speech?
1-Paired cranial nerves for phonation, resonance, articulation, prosody
2-Spinal nerves for respiration & prosody
What are the supportive or glial cells?
1-Schwann cells - myelin sheath around axons in PNS
2-Oligodendrogliocytes - myelin sheath aroun axons in CNS
3-Microglia - remove dead cells
4-Astrocytes - connective tissue of CNS
*10x more glial cells than neourons