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33 Cards in this Set

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  • Back
Describe the blood supply to the cerebellum
superior cerebellar, PICA, AICA
What is the function of the flocculonodular lobe
Forms the vestibulocerebellum, control of equilibrium, balance, and eye movements (VOR)
What is the function of the vermis
part of the spinocerebellum, control of axial and proximal limb movements
What is the function of the intermediate one of the cerebellar hemisphere
part of the spinocerebellum, control of distal limb movements
What is the function of the lateral zone of the cerebellar hemisphere
part fthe cerebrocerebellum, planning and initiating movements
What is the major output pathway from the cerebellar cortex (what type of cell carries the info)
purkinje cells, inhibitory (note purkinje cells are output from the cerebellar CORTEX and are inhibitory, DCN are the output from the cerebellum as a whole and are excitatory)
What are the two types of afferent fibers to the cerebellum? What type of info do they carry
climbing fiber-from contralateral ION, mossy fiber-from all other sources
What are the contents of the molecular layer of the cerebellar cortex
dendrites of purkinje cells, parallel fibers from axons of granule cells, climbing fibers from ION, stellate and basket cells
what is the function of granular cells
Receive input from mossy fibers in granule layer, send axons into the molecular layer that become parallel fibers where they form excitatory synapses on purkinje cells
What do the purkinje cells synapse onto/ major output neurons of the cerebellum
Deep cerebellar nuclei from lateral to medial: Dentate, emboliform, globose, fastigial (Don't eat greasy food)
Describe the synaptic circut of the climibing fibers
Climbing fiber (+) purkinje cell (-) DCN
Describe the synaptic circut of mossy fibers
mossy fiber (+)granule cell (+)parallel fibers (+) purkinje cells (-) DCN
How do mossy fibers and climbing fibers differ in terms of synaptic connections
Both eventually excit purkinje cells. Climbing fibers for direct excitatory synapses on the purkinje cells, mossy fibers form excitatory synapses on granule cells which then branch into parallel fibers forming excitatory synapses on purkinje cells
What is the function of basket and stellate cells
Found in the molecular layer, excited by input from granular cell parallel fibers, form inhibitory synapses with purkinje cells
What is the function of golgi cells
Receive input from granule cell pareallel fibers, form inhibitory synapse with granule cell to provide feedback inhibition
Describe the path of afferent information from the vestibular system to the cerebellum
info from the vestibular nuclei as well as the SC and VC travel via the juxtarestiform body to the ipsilateral flocculonodular lobe
What three tracts travel within the inferior cerebellar peduncle? What info are they carrying
1. Dorsal spinocerebellar-sensory info from ipsilateral lower extremeties 2. Cuneocerebellar-sensory info from ipsiateral upper extremity 3. Olivocerebellar-infrom from contralatearl ION
Describe how sensory information from the lower extremity reaches the cerebellum
primary sensory info travels via the fasiculus gracilis to the dorsal nucleus of Clark. The info then travels on the dorsal spinocerebellar track through the spinal cord and lower medulla up through the inferior cerebellar peduncle to the spinocerebellum (vermis and intermediate zone)
Describe how information from the upper extremity reaches the cerebellum
INformation travels via the fasiculus cuneatus to the cuneat nucleus. THe info is then carried by the cuneocerebellar track from the ipsilateral spinal cord and lower medulla to the spinocerebellum (vermis and intermediate zone)
What tract makes up the MCP? What type of information is it carrying
MCP=cortico-ponto-cerebellar tract, carries info from contralatearl cortex via pontine nuclei to the cerebrocerebellum (lateral zone)
Describe how information from the cortex reaches the cerebellum
Info from the contralateral cortex enters the cerebrocerebellum via pontine nuclei on the cortico-ponto-cerebellar tract via the MCP
What tract makes up the superior cerebellar peduncle? What type of info is carried
Ventral spinocerebellar tract carrring info from contralatearl spinal cord projecting to contralateral spinocerebellum (double cross=ipsilateral sxs), 2. efferent outputs to DCN
Describe the two monoaminergic inputs to the cerebellum
1. serotoninergic fibers from raphe nuclei 2. noradrenergic fibers from the locus ceruleus
Describe the efferent pathway from the flocculonodular lobe
FLN=> vestibular nuclei, controls eyemovemetn and body equilibrium
Describe the efferent pathway from the vermis.
Two pathways for control of axial and proximal motorl fxns, control of ongoing movement 1. vermis=>fastigial nucleus=>brain stem regions=>medial descending systems=> proximal muscles 2. vermis=>fastigial nucleus=>thalamus=>motor and premotor cortex=>axial and proxmial muscle control
Describe the effernt pathway from the intermediate zone
Two pathways to control distal muslces 1. intermediate zone=>interposed nuclei=>red nucelus (brainstem)=>lateral descending systems=>distal limb muscles. 2. intermediate zone=>interposed nuclei=>thalamus=>motor and premotor cortex=>distal limb muslces via corticospinal tract
Describe the efferent pathway from the lateral zone of the cerebellum
For planning, initiation, and timing of voluntary movements. Lateral zone=>dentate nucleus=> via red nucleus or directly=>thalamus=>motor and premotor cortex=>spinal cord via corticospinal track=>back to lateral zone via corticopontine tract
What is the function of the corticopontocerebellar tract
Carrys info from cortex to cerebellum, gives information about plans for movement from motor and premotor cortex via the corticopontocerebellar tract
What is the function of the dorsal spinocerebellar tact
carrys info from the sensory periphery during the course of movement
What is the function of the ventral spinocerebellar tract
monitors the integration of descending and peripheral information reguarding movement in the spinal cord, enteres cerebellum via SCP
What is th efunction of the dentatorubrothalamic tract
Carrys info from latral zone to motor cortex, spinal cord and back, allows for adjustment of the output of the motor system
On which side of the body do cerebellar lesions typicall cause motor signs
ipsilateral
What are the major signs of cerebellar dysfunction
ataxia, hypotonia, intentional tremor, dysdiadochokinesia, dysmetria, nystagmus, titubation