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38 Cards in this Set
- Front
- Back
What two facial prominences make up the first arch?
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Maxillary and Mandibular
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thickenings of the surface ectoderm
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Placode
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Name the 3 placodes
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Otic, Lens and nasal
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Depression in the center of 5 facial prominences
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Stomodeum
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What communicates with the pharynx after the breakdown of the oropharyngeal (buccopharyngeal) membrane and around what day?
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Stomodeum (Floor forms the ectodermal surface of the membrane) around day 24
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What forms the midline of the nose, part of the nasal septum and intermaxillary segment?
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Medial nasal prominences migrate medially and merge
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What merges around week 4 to form lower lip, jaw, inferior face ?
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Mandibular prominences
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What forms the side of the nose?
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Lateral nasal prominences
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What forms the philtrum (midline portion) of the upper lip?
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Labial component of intermaxiallary segment of medial nasal prominence
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What forms the premaxillary part of the maxilla?
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Upper jaw component of intermaxillary segment of medial nasal prominence
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What forms the primary palate?
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Palatal component of the intermaxillary segment of the medial nasal prominence
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What forms the cheek, most of the maxilla, most of the upper lip and secondary palate?
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Maxillary prominence
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Where is the furrow where the maxillary prominence fuses with the lateral nasal prominence?
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Nasolacrimal groove
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What does the ectoderm in the nasolacrimal groove form?
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Nasolacrimal sac and duct
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The external ear develops from mesenchyme of what arches?
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1st and 2nd
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When does the palate form and when is the most critical period?
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Between weeks 5-12, most critical from 6-9
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Where is the intermaxillary segment dervied?
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Medial Nasal Prominence
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What forms the primary palate?
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Intermaxillary segment of the medial nasal prominence
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What forms the secondary palate?
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Fusion of palatine shelves
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Where are the palatine shelves derived from?
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Maxillary prominence
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The Posterior secondary palate has no bone & forms what?
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the soft palate + uvula.
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What area of the palate is the last to fuse, around 12 weeks?
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Uvula
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HARD PALATE is where and what type of bone?
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Primary palate and rostral secondary palate: intramembranous bone
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SOFT PALATE is where and is made of what?
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Caudal secondary palate: skeletal muscle
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What marks the fusion of the primary and secondary palates?
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Incisive Foramen
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separates the nasal pits from the primitive oral cavity.
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Oronasal membrane
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When does the oronasal membrane rupture and what does it form?
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wk 6 to form PRIMITIVE CHOANAE -- so communication established between nasal and oral cavities.
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Formation of the SECONDARY PALATE partially separates the nasal and oral cavities.-- leading to formation of the?
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DEFINITIVE CHOANAE.
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NASAL SEPTUM from the medial nasal prominences grows down and fuses with the midline region of the definitive palate -- forming the?
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perpendicular plate of the ETHMOID plus the VOMER.
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What are the only two sinuses present at birth?
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maxillary and part of ethmoid
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What is considered the dividing landmark between anterior and posterior cleft deformities?
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The incisive foramen
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Is cleft lip anterior or posterior defect?
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anterior
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Is cleft palate an anterior or posterior defect?
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posterior
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Anterior defects are due to what?
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Due to failure of fusion of maxillary prominences with the fused medial nasal prominences.
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Posterior defects are due to what?
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Due to failure of fusion of the palatine shelves with one another, with the nasal septum & with the posterior margin of the primary palate.
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What is more common in females, cleft lip or cleft palate?
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Cleft palate
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What increases with increasing maternal age, cleft lip or cleft palate?
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Cleft lip
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How does a teratogen produce cleft lip/palate?
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Interfere with migration of neural crest cells into facial primordia and cause a lack of mesenchyme to work with.
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