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38 Cards in this Set

  • Front
  • Back
What two facial prominences make up the first arch?
Maxillary and Mandibular
thickenings of the surface ectoderm
Placode
Name the 3 placodes
Otic, Lens and nasal
Depression in the center of 5 facial prominences
Stomodeum
What communicates with the pharynx after the breakdown of the oropharyngeal (buccopharyngeal) membrane and around what day?
Stomodeum (Floor forms the ectodermal surface of the membrane) around day 24
What forms the midline of the nose, part of the nasal septum and intermaxillary segment?
Medial nasal prominences migrate medially and merge
What merges around week 4 to form lower lip, jaw, inferior face ?
Mandibular prominences
What forms the side of the nose?
Lateral nasal prominences
What forms the philtrum (midline portion) of the upper lip?
Labial component of intermaxiallary segment of medial nasal prominence
What forms the premaxillary part of the maxilla?
Upper jaw component of intermaxillary segment of medial nasal prominence
What forms the primary palate?
Palatal component of the intermaxillary segment of the medial nasal prominence
What forms the cheek, most of the maxilla, most of the upper lip and secondary palate?
Maxillary prominence
Where is the furrow where the maxillary prominence fuses with the lateral nasal prominence?
Nasolacrimal groove
What does the ectoderm in the nasolacrimal groove form?
Nasolacrimal sac and duct
The external ear develops from mesenchyme of what arches?
1st and 2nd
When does the palate form and when is the most critical period?
Between weeks 5-12, most critical from 6-9
Where is the intermaxillary segment dervied?
Medial Nasal Prominence
What forms the primary palate?
Intermaxillary segment of the medial nasal prominence
What forms the secondary palate?
Fusion of palatine shelves
Where are the palatine shelves derived from?
Maxillary prominence
The Posterior secondary palate has no bone & forms what?
the soft palate + uvula.
What area of the palate is the last to fuse, around 12 weeks?
Uvula
HARD PALATE is where and what type of bone?
Primary palate and rostral secondary palate: intramembranous bone
SOFT PALATE is where and is made of what?
Caudal secondary palate: skeletal muscle
What marks the fusion of the primary and secondary palates?
Incisive Foramen
separates the nasal pits from the primitive oral cavity.
Oronasal membrane
When does the oronasal membrane rupture and what does it form?
wk 6 to form PRIMITIVE CHOANAE -- so communication established between nasal and oral cavities.
Formation of the SECONDARY PALATE partially separates the nasal and oral cavities.-- leading to formation of the?
DEFINITIVE CHOANAE.
NASAL SEPTUM from the medial nasal prominences grows down and fuses with the midline region of the definitive palate -- forming the?
perpendicular plate of the ETHMOID plus the VOMER.
What are the only two sinuses present at birth?
maxillary and part of ethmoid
What is considered the dividing landmark between anterior and posterior cleft deformities?
The incisive foramen
Is cleft lip anterior or posterior defect?
anterior
Is cleft palate an anterior or posterior defect?
posterior
Anterior defects are due to what?
Due to failure of fusion of maxillary prominences with the fused medial nasal prominences.
Posterior defects are due to what?
Due to failure of fusion of the palatine shelves with one another, with the nasal septum & with the posterior margin of the primary palate.
What is more common in females, cleft lip or cleft palate?
Cleft palate
What increases with increasing maternal age, cleft lip or cleft palate?
Cleft lip
How does a teratogen produce cleft lip/palate?
Interfere with migration of neural crest cells into facial primordia and cause a lack of mesenchyme to work with.